New Animal Model to Mimic Spastic Cerebral Palsy: The Brain-Damaged Pig Preparation

2008 ◽  
Vol 11 (3) ◽  
pp. 196-201 ◽  
Author(s):  
Juan Carlos M. Andreani ◽  
Cristina Guma
2018 ◽  
Vol 2018 ◽  
pp. 1-14 ◽  
Author(s):  
Gaétan Ickx ◽  
Samar M. Hatem ◽  
Inmaculada Riquelme ◽  
Kathleen M. Friel ◽  
Camille Henne ◽  
...  

Aim. This observational study aimed at assessing the prevalence of visuospatial attention deficits in children with unilateral spastic cerebral palsy (USCP), taking into consideration the affected hemibody and the localization of the brain lesion. Method. Seventy-five children with USCP were assessed with four visuospatial attention tests: star cancellation, Ogden figure copy, line bisection, and proprioceptive pointing. Results. A majority (64%) of children with USCP presented a deficit in at least one test compared to the reference values. The alterations observed in children with left or right USCP were related to egocentric or allocentric neglect, respectively. Children with cortico/subcortical lesion presented more often visuospatial attention deficits than children with periventricular lesion. Visuospatial attention deficits were not associated with brain lesion locations. Interpretation. Visuospatial attention deficits are prevalent in children with USCP and should be taken into account during their rehabilitation process. The present results shed new light on the interpretation of motor impairments in children with USCP as they may be influenced by the frequent presence of visuospatial deficits.


Physiology ◽  
2019 ◽  
Vol 34 (3) ◽  
pp. 216-229 ◽  
Author(s):  
Joline E. Brandenburg ◽  
Matthew J. Fogarty ◽  
Gary C. Sieck

Spastic cerebral palsy (CP), despite the name, is not consistently identifiable by specific brain lesions. CP animal models focus on risk factors for development of CP, yet few reproduce the diagnostic symptoms. Animal models of CP must advance beyond risk factors to etiologies, including both the brain and spinal cord.


2014 ◽  
Vol 21 (06) ◽  
pp. 1166-1170
Author(s):  
Naeem Mohammad Mansha ◽  
Sumair Anwar ◽  
Itaat Ullah Khan Afridi ◽  
Shazia Maqbool

Background: Cerebral Palsy is a disorder of movement and postural balance due to insult to the brain. The injury to the developing brain may be prenatal, natal or postnatal. The diagnosis is clinical mainly. The spastic Cerebral Palsy is classified into monoplegic, hemiplegic, diplegic, and quadriplegic types. There is a difference in the frequency of these types of Cerebral Palsy in different studies. The patterns of various forms of Cerebral Palsy emerge gradually with a delay in developmental milestones. A spectrum of associated developmental disabilities has been found to be common in these children. Management is through a multi-disciplinary approach. Objectives: To find out the frequency of different types of Cerebral Palsy and degree of associated developmental delay. Methodology: A cross sectional study was carried out for a period of six months (October 1, 2006 to March 31, 2007) at The Children’s Hospital & Institute of Child Health Lahore. 100 Cases diagnosed as Cerebral Palsy on clinical basis were assessed for the type of cerebral palsy and the degree of associated developmental delay. Results: Out of the total 100 patients 54% had quadriplegia, 32% had diplegia, 10% had himiplegia and 4% had monoplegia. The total fifty-four cases of quadriplegic cerebral palsy 54 had developmental delay and amongst them 4 (7%) had mild delay, 16 (30%) had moderate delay while 34 (63%) had severe delay. Amongst the total forty-six other three types of cerebral palsy 12 (26%) had mild delay, 6 (13%) had moderate delay and 28 (61%) had severe delay. The P-value was >0.05. Conclusions: Quadriplegic is the commonest type of CP, associated with the factors (peri-natal more than socio-demographic) and had significant effect on the developmental parameters.


2008 ◽  
Vol 23 (11) ◽  
pp. 1267-1274 ◽  
Author(s):  
Yun Wu ◽  
Zhen Jin ◽  
Ke Li ◽  
Zhong-Li Lu ◽  
Virginia Wong ◽  
...  

2015 ◽  
pp. 44-49
Author(s):  
Nu Van Anh Ton

Objective: Cerebral palsy is characterized by non-progressive abnormalities in brain, that is the real burden to family and society. Finding the signs of clinical, subclinical, disorders as well as co-morbidities in children with cerebral palsy are needed. If detected early, aggressive treatment and rehabilitation will significantly improve mobility, reduce the level of disability and the child integrate into the community. Material and methods: Children diagnosed with cerebral palsy, with cross-sectional descriptive methods. Time from 6/ 2012 to 3/2014. Results: study on 45 children with cerebral palsy: older than 36 months accounted for 60.0%; boys more than girls accounted 57.8%; seizure is the common reason the child to the hospital (accounted for the highest percentage of 24.4%). Spastic cerebral palsy can account for the highest proportion of 48.9%, ataxia may account for the lowest percentage of 2.2%; quadriplegic highest percentage of 51.1%; level V cerebral palsy (not self- activity even when have supported devices) accounted for a high proportion of 51.1%, pneumonia, seizures and saliva flow is the most common disorder in children with cerebral palsy, with a history of risk factors for birth asphyxia high proportion least 33.3%; detection epileptic wave in children with cerebral palsy through EEG high proportion of 53%, there is physical injury in the brain in children with cerebral palsy through CTscanner high percentage of 62.5%. Conclusion: To avoid the risk of cerebral palsy, special asphyxia, and do the EEG records, imaging diagnostic to identify clearly brain lesions for better outcome. Key words: Cerebral palsy


2015 ◽  
Vol 46 (S 01) ◽  
Author(s):  
J. Delgado ◽  
M. Arroyo ◽  
R. Pulido ◽  
S. Grunt

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