In Vitro Response of Animal Arteries to Serum of Migraineurs

1979 ◽  
Vol 19 (4) ◽  
pp. 209-213
Author(s):  
G. Nattero ◽  
J. Franzone ◽  
F. Croce ◽  
D. Bisbocci ◽  
E. Genazzani
Keyword(s):  
In Vitro Response

scholarly journals Microstructure and surface texture driven improvement in in-vitro response of laser surface processed AZ31B magnesium alloy

2021 ◽  
Author(s):  
Tso-Chang Wu ◽  
Sameehan S. Joshi ◽  
Yee-Hsien Ho ◽  
Mangesh V. Pantawane ◽  
Subhasis Sinha ◽  
...  
Keyword(s):  
Magnesium Alloy ◽  
Surface Texture ◽  
Laser Surface ◽  
Az31b Magnesium Alloy ◽  
In Vitro Response

scholarly journals Loss of Nitric Oxide Induces Fibrogenic Response in Organotypic 3D Co-Culture of Mammary Epithelia and Fibroblasts—An Indicator for Breast Carcinogenesis

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2815
Author(s):  
Gang Ren ◽  
Xunzhen Zheng ◽  
Vandana Sharma ◽  
Joshua Letson ◽  
Andrea L. Nestor-Kalinoski ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Culture System ◽  
Epithelial Mesenchymal Transition ◽  
Precancerous Lesions ◽  
Three Dimensional ◽  
Epidemiological Studies ◽  
Mesenchymal Transition ◽  
In Vitro Response ◽  
Mammary Epithelia

Excessive myofibroblast activation, which leads to dysregulated collagen deposition and the stiffening of the extracellular matrix (ECM), plays pivotal roles in cancer initiation and progression. Cumulative evidence attests to the cancer-causing effects of a number of fibrogenic factors found in the environment, diseases and drugs. While identifying such factors largely depends on epidemiological studies, it would be of great importance to develop a robust in vitro method to demonstrate the causal relationship between fibrosis and cancer. Here, we tested whether our recently developed organotypic three-dimensional (3D) co-culture would be suitable for that purpose. This co-culture system utilizes the discontinuous ECM to separately culture mammary epithelia and fibroblasts in the discrete matrices to model the complexity of the mammary gland. We observed that pharmaceutical deprivation of nitric oxide (NO) in 3D co-cultures induced myofibroblast differentiation of the stroma as well as the occurrence of epithelial–mesenchymal transition (EMT) of the parenchyma. Such in vitro response to NO deprivation was unique to co-cultures and closely mimicked the phenotype of NO-depleted mammary glands exhibiting stromal desmoplasia and precancerous lesions undergoing EMT. These results suggest that this novel 3D co-culture system could be utilized in the deep mechanistic studies of the linkage between fibrosis and cancer.

In vitro response of Ichthyophthirius multifiliis to sera from immune channel catfish

1987 ◽  
Vol 31 (sa) ◽  
pp. 203-208 ◽  
Author(s):  
T. G. Clark ◽  
H. W. Dickerson ◽  
J. B. Gratzek ◽  
R. C. Findly
Keyword(s):  
Channel Catfish ◽  
Ichthyophthirius Multifiliis ◽  
In Vitro Response

Interrenal activity in the female lizard Lagerta vivipara J.: In vitro response to ACTH 1–39 and to [SAR1, VAL5] angiotensin II (ANG II)

1988 ◽  
Vol 30 (1-6) ◽  
pp. 457-460 ◽  
Author(s):  
Chantal Dauphin-Villemant ◽  
François Leboulenger ◽  
Françoise Xavier ◽  
Hubert Vaudry
Keyword(s):  
Angiotensin Ii ◽  
Ang Ii ◽  
In Vitro Response ◽  
Female Lizard

In vitro response to mitogens by duck splenic mononuclear cells

1995 ◽  
Vol 59 (3) ◽  
pp. 242-246 ◽  
Author(s):  
K Vickery ◽  
A Pajkos ◽  
Y Cossart
Keyword(s):  
Mononuclear Cells ◽  
In Vitro Response

Testicular testosterone concentration and in vitro response to HCG in normal and in testosterone immunized rabbits

Steroids ◽  
1975 ◽  
Vol 25 (3) ◽  
pp. 379-386 ◽  
Author(s):  
E. Nieschlag ◽  
W. Tekook ◽  
K.H. Usadel ◽  
H.K. Kley ◽  
H.L. Krüskemper
Keyword(s):  
Testosterone Concentration ◽  
In Vitro Response

Stimulated Platelets Release Factor(s) Affecting the In Vitro Response of Human Polymorphonuclear Cells

1990 ◽  
Vol 48 (1) ◽  
pp. 7-14 ◽  
Author(s):  
Domenico Del Principe ◽  
Adriana Menichelli ◽  
Stefano Di Giulio ◽  
Walter De Matteis ◽  
Massimo Giordani ◽  
...  
Keyword(s):  
Polymorphonuclear Cells ◽  
Release Factor ◽  
In Vitro Response

Malignant Hyperthermia in a Child with Duchenne Muscular Dystrophy

PEDIATRICS ◽  
1983 ◽  
Vol 71 (1) ◽  
pp. 118-119
Author(s):  
HOWARD M. KELFER ◽  
WILLIAM D. SINGER ◽  
ROBERT N. REYNOLDS
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Side Effects ◽  
Muscular Dystrophy ◽  
Malignant Hyperthermia ◽  
Muscle Biopsy ◽  
Biopsy Specimen ◽  
Laboratory Findings ◽  
Anesthetic Agents ◽  
In Vitro Response

Patients with Duchenne muscular dystrophy (DMD) are susceptible to numerous adverse intraoperative and postoperative side effects of anesthetic agents. These include: hyperthermia and hyperkalemia,1,2 systemic acidosis,3 cardiac abnormalities (tachycardia, arrhythmia, arrest),2-5 rhabdomyolysis,2-6 as well as death.2,5 These clinical and laboratory findings are similar to those associated with malignant hyperthermia (MH).7,8 Until this time no one has confirmed the association of MH, as reflected by these clinical phenomena, in a patient with DMD. We present a patient who manifested many features of MH immediately following confirmatory muscle biopsy for DMD under general anesthesia. In vitro response to testing of a muscle biopsy specimen was consistent with a diagnosis of malignant hyperthermia.

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