Predictors of Mortality in Alcoholic Women: A Prospective Follow-up Study

Abstract The burden of multidrug-resistant tuberculosis (MDR-TB) related to mortality in resource-poor countries remains high. This study aimed to estimate the incidence and predictors of death among MDR-TB patients in central Ethiopia. A retrospective follow-up study was conducted at three hospitals in the Amhara region on 451 patients receiving treatment for MDR-TB from September 2010 to January 2017. Data were collected from patient registration books, charts and computer databases. Data were fitted to a parametric frailty model and survival was expressed as an adjusted hazard ratio (AHR) with a 95% confidence interval (CI). The median follow-up time of participants was 20 months (interquartile range: 12, 22) and 46 (10.20%) of patients died during this period. The incidence rate of mortality was 7.42 (95% CI 5.56–9.91)/100 person-years. Older age (AHR = 1.04, 95% CI 1.01–1.08), inability to self-care (AHR = 13.71, 95% CI 5.46–34.40), co-morbidity (AHR = 5.74, 95% CI 2.19–15.08), low body mass index (AHR = 4.13, 95% CI 1.02–16.64), acute lung complications (AHR = 4.22, 95% CI 1.66–10.70) and lung consolidation at baseline (AHR = 5.27, 95% CI 1.06–26.18) were independent predictors of mortality. Most of the identified predictor factors of death in this study were considered to be avoidable if the TB programme had provided nutritional support for malnourished patients and ensured a close follow-up of the elderly, and patients with co-morbidities.

Download Full-text

Predictors of mortality in patients with peripheral vascular disease. A prospective follow-up study

The British Journal of Diabetes ◽

10.1177/14746514040040030901 ◽

2004 ◽

Vol 4 (3) ◽

pp. 196-200 ◽

Cited By ~ 1

Author(s):

Constantinos G Missouris ◽

Rigas G Kalaitzidis ◽

Sally M Kerry ◽

Francesco P Cappuccio

Keyword(s):

Vascular Disease ◽

Peripheral Vascular Disease ◽

Peripheral Vascular ◽

Predictors Of Mortality ◽

Follow Up Study

Download Full-text

Predictors of mortality in men and women aged 90 and older: a nine-year follow-up study in the Vitality 90+ study

Age and Ageing ◽

10.1093/ageing/aft030 ◽

2013 ◽

Vol 42 (4) ◽

pp. 468-475 ◽

Cited By ~ 40

Author(s):

K. Tiainen ◽

T. Luukkaala ◽

A. Hervonen ◽

M. Jylha

Keyword(s):

Men And Women ◽

Predictors Of Mortality ◽

Follow Up Study

Download Full-text

Predictors of mortality among adult people living with HIV/AIDS on antiretroviral therapy at Suhul Hospital, Tigrai, Northern Ethiopia: a retrospective follow-up study

Journal of Health Population and Nutrition ◽

10.1186/s41043-019-0194-0 ◽

2019 ◽

Vol 38 (1) ◽

Author(s):

Kebede Haile Misgina ◽

Meresa Gebremedhin Weldu ◽

Tewodros Haile Gebremariam ◽

Negassie Berhe Weledehaweria ◽

Haileslasie Berhane Alema ◽

...

Keyword(s):

Immune Deficiency ◽

Opportunistic Infections ◽

Clinical Stage ◽

People Living With Hiv ◽

Northern Ethiopia ◽

Predictors Of Mortality ◽

Follow Up Study ◽

Living With Hiv ◽

Hiv Aids

Abstract Background Ethiopia is striving to achieve a goal of “zero human immune deficiency virus/acquired immune deficiency syndrome (HIV/AIDS)-related deaths.” However, little has been documented on the factors that hamper the progress towards achieving this goal. Therefore, the ultimate aim of this study was to determine predictors of mortality among adult people living with HIV/AIDS on antiretroviral therapy (ART). Methods A retrospective follow-up study was employed on all adult HIV/AIDS patients who started ART between January 1 and December 30, 2010, at Suhul Hospital, Tigrai Region, Northern Ethiopia. Data were collected by trained fourth-year Public Health students using a checklist. Finally, the collected data were entered into SPSS version 16. Then after, Kaplan-Meier curves were used to estimate survival probability, the log-rank test was used for comparing the survival status, and Cox proportional hazards model were applied to determine predictors of mortality. Results The median follow-up period was 51 months (ranging between 1 and 60 months, inter-quartile range (IQR) = 14 months). At the end of follow-up, 37 (12.5%) patients were dead. The majority of these cumulative deaths, 19 (51.4%) and 29 (78.4%), occurred within 3 and 4 years of ART initiation respectively. Consuming alcohol (adjusted hazard ratio (AHR) = 2.23, 95% CI = 1.15, 4.32), low body weight (AHR = 2.38, 95% CI = 1.03, 5.54), presence of opportunistic infections (AHR = 2.18, 95% CI = 1.09, 4.37), advanced WHO clinical stage (AHR = 2.75, 95% CI = 1.36, 5.58), and not receiving isoniazid prophylactic therapy (AHR = 3.00, 95% CI = 1.33, 6.74) were found to be independent predictors of mortality. Conclusion The overall mortality was very high. Baseline alcohol consumption, low body weight, advanced WHO clinical stage, the presence of opportunistic infections, and not receiving isoniazid prophylactic therapy were predictors of mortality. Strengthening behavioral and nutritional counseling with close clinical follow-up shall be given much more emphasis in the ART care and support program.

Download Full-text