Fine Mapping of Polymorphic Alcohol-Related Quantitative Trait Loci Candidate Genes Using Interval-Specific Congenic Recombinant Mice

2002 ◽  
Vol 26 (11) ◽  
pp. 1603-1608 ◽  
Author(s):  
Marissa A. Ehringer ◽  
Jessica Thompson ◽  
Otakuye Conroy ◽  
Fan Yang ◽  
Raquel Hink ◽  
...  
Keyword(s):  
Quantitative Trait Loci ◽  
Candidate Genes ◽  
Fine Mapping ◽  
Quantitative Trait ◽  
Trait Loci ◽  
Recombinant Mice

Fine mapping of murine asthma quantitative trait loci and analyses ofPtgs1andMrc1as positional candidate genes

DNA Sequence ◽  
2007 ◽  
Vol 18 (3) ◽  
pp. 190-195 ◽  
Author(s):  
Xingnan Li ◽  
Rebekah I. Fleis ◽  
Dennis M. Shubitowski ◽  
Ravisankar A. Ramadas ◽  
Susan L. Ewart
Keyword(s):  
Quantitative Trait Loci ◽  
Candidate Genes ◽  
Fine Mapping ◽  
Quantitative Trait ◽  
Positional Candidate ◽  
Trait Loci

Fine mapping quantitative trait loci for feed intake and feed efficiency in beef cattle1

2009 ◽  
Vol 87 (1) ◽  
pp. 37-45 ◽  
Author(s):  
E. L. Sherman ◽  
J. D. Nkrumah ◽  
C. Li ◽  
R. Bartusiak ◽  
B. Murdoch ◽  
...  
Keyword(s):  
Quantitative Trait Loci ◽  
Fine Mapping ◽  
Feed Intake ◽  
Quantitative Trait ◽  
Feed Efficiency ◽  
Trait Loci

scholarly journals A Fine mapping quantitative trait loci that underlie resistance to soybean sudden death syndrome using NILs and SNPs.

2018 ◽  
pp. 583-591
Author(s):  
Yi Chen Lee ◽  
M Javed Iqbal ◽  
Victor N Njiti ◽  
Stella Kantartzi ◽  
David A. Lightfoot
Keyword(s):  
Quantitative Trait Loci ◽  
Sudden Death ◽  
Candidate Genes ◽  
Quantitative Trait ◽  
Soybean Cyst Nematode ◽  
Snp Markers ◽  
Sudden Death Syndrome ◽  
Isogenic Line ◽  
Trait Loci ◽  
Glycine Max L

Soybean (Glycine max (L.) Merr.) cultivars differ in their resistance to sudden death syndrome (SDS), caused by Fusarium virguliforme. Breeding for improving SDS response has been challenging, due to interactions among the 18-42 known resistance loci. Four quantitative trait loci (QTL) for resistance to SDS (cqRfs–cqRfs3) were clustered within 20 cM of the rhg1 locus underlying resistance to soybean cyst nematode (SCN) on Chromosome (Chr.) 18. Another locus on Chr. 20 (cqRfs5) was reported to interact with this cluster. The aims here were to compare the inheritance of resistance to SDS in a near isogenic line (NIL) population that was fixed for resistance to SCN but segregated at two of the four loci (cqRfs1 and cqRfs) for SDS resistance; to examine the interaction with the locus on Chr. 20; and to identify candidate genes underlying QTL. Used were; a NIL population derived from residual heterozygosity in an F5:7 recombinant inbred line EF60 (lines 1-38); SDS response data from two locations and years; four segregating microsatellite and 1,500 SNP markers. Polymorphic regions were found from 2,788 Kbp to 8,938 Kbp on Chr. 18 and 33,100 Kbp to 34,943 Kbp on Chr. 20 that were significantly (0.005 < P > 0.0001) associated with resistance to SDS. The QTL fine maps suggested that the two loci on Chr. 18 were three loci (cqRfs1, cqRfs, and cqRfs19). Candidate genes were inferred.  An epistatic interaction was inferred between Chr. 18 and Chr. 20 loci. Therefore, SDS resistance QTL were both complex and interacting.

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