Self-Hardening Microspheres of Calcium Phosphate Cement with Collagen for Drug Delivery and Tissue Engineering in Bone Repair

2011 ◽  
Vol 94 (2) ◽  
pp. 351-354 ◽  
Author(s):  
Jeong-Hui Park ◽  
Gil-Su Lee ◽  
Ueon Sang Shin ◽  
Hae-Won Kim
2009 ◽  
Vol 5 (7) ◽  
pp. 2752-2762 ◽  
Author(s):  
M. Espanol ◽  
R.A. Perez ◽  
E.B. Montufar ◽  
C. Marichal ◽  
A. Sacco ◽  
...  

Author(s):  
X Li ◽  
D Li ◽  
B Lu ◽  
L Wang ◽  
Z Wang

The ability to have precise control over internal channel architecture, porosity, and external shape is essential for tissue engineering. The feasibility of using indirect stereo-lithography (SL) to produce scaffolds from calcium phosphate cement materials for bone tissue engineering has been investigated. The internal channel architecture of the scaffolds was created by removal of the negative resin moulds made with SL. Scanning electron microscopy (SEM) showed highly open, well-interconnected channel architecture. The X-ray diffraction examination revealed that the hydroxyapatite phase formed at room temperature in the cement was basically stable up to 850 °C. There was no phase decomposition of hydroxyapatite, although the crystallinity and grain size were different. The ability of resulting structure to support osteoblastic cells culture was tested in vitro. Cells were evenly distributed on exterior surfaces and grew into the internal channels of scaffolds. To exploit the ability of this technique, anatomically shaped femoral supracondylar scaffolds with 300-800 μm interconnected channels were produced and characterized.


2011 ◽  
Vol 16 (5) ◽  
pp. 628-635 ◽  
Author(s):  
Wei Zhao ◽  
Jia-yu Lu ◽  
Yong-ming Hao ◽  
Xiu-li Zhang ◽  
Xiao-hui Qu ◽  
...  

2012 ◽  
Vol 95 (12) ◽  
pp. 4021-4021 ◽  
Author(s):  
Tao Yu ◽  
Jiandong Ye ◽  
Chengying Gao ◽  
Long Yu ◽  
Yingjun Wang

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