Influence of two barrier membranes on staged guided bone regeneration and osseointegration of titanium implants in dogs. Part 2: augmentation using bone graft substitutes

2011 ◽  
Vol 23 (3) ◽  
pp. 308-315 ◽  
Author(s):  
Ilja Mihatovic ◽  
Jürgen Becker ◽  
Vladimir Golubovic ◽  
Andrea Hegewald ◽  
Frank Schwarz
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Titanium Implants ◽  
Barrier Membranes ◽  
Bone Graft Substitutes

scholarly journals Horizontal-guided Bone Regeneration using a Titanium Mesh and an Equine Bone Graft

2015 ◽  
Vol 16 (2) ◽  
pp. 154-162 ◽  
Author(s):  
Danilo Alessio Di Stefano ◽  
Gian Battista Greco ◽  
Lorenzo Cinci ◽  
Laura Pieri
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Bone Sample ◽  
Successful Outcome ◽  
Autogenous Bone ◽  
Titanium Mesh ◽  
Ridge Augmentation ◽  
Stereolithographic Model ◽  
Equine Bone

ABSTRACT Aim The present work describes a horizontal ridge augmentation in which a titanium mesh was preshaped by adapting it to a stereolithographic model of the patient's jaw that was fabricated from CT scans. Background Guided bone regeneration (GBR) involves covering the augmentation site with a long-lasting barrier to protect it from the invasion of surrounding soft tissues. Among barriers, titanium meshes may provide a successful outcome, but the intraoperatory time needed to shape them is a disadvantage. Case description The 54-year-old patient, missing the right mandibular second bicuspid, first molar, and second molar, had her atrophic ridge augmented with a 30:70 mixture of autogenous bone and equine, enzyme-deantigenic collagenpreserved bone substitute. Two conical implants were inserted concomitantly in the second bicuspid and first molar positions, and the site was protected with the preshaped mesh. Four months later, the titanium mesh was retrieved, a bone sample was collected, and histological and histomorphometric analyses were performed. Provisional and definitive prostheses were then delivered, and follow-up controls were performed for up to 24 months. Conclusion Preshaping the mesh on a model of the patient's mandible shortened the surgical time and enabled faster mesh placement. Two years after surgery, the implants were perfectly functional, and the bone width was stable over time as shown by radiographic controls. Histological analysis of the bone sample showed the heterologous biomaterial to be biocompatible and undergoing advanced remodeling and replacement with newly formed bone. Clinical significance Preshaping a titanium mesh over a stereolithographic model of the patient's jaw allowed for a significant reduction of the intraoperative time and may be therefore, advisable in routine practice. How to cite this article Di Stefano DA, Greco GB, Cinci L, Pieri L. Horizontal-guided Bone Regeneration using a Titanium Mesh and an Equine Bone Graft. J Contemp Dent Pract 2015;16(2):154-162.

scholarly journals Comparative In Vivo Analysis of the Integration Behavior and Immune Response of Collagen-Based Dental Barrier Membranes for Guided Bone Regeneration (GBR)

Membranes ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 712
Author(s):  
Milena Radenković ◽  
Said Alkildani ◽  
Ignacio Stoewe ◽  
James Bielenstein ◽  
Bernd Sundag ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bone Regeneration ◽  
Barrier Function ◽  
Guided Bone Regeneration ◽  
Collagen Membrane ◽  
Cellular Infiltration ◽  
Barrier Membranes ◽  
Tissue Integration ◽  
Tissue Reactions

Collagen-based resorbable barrier membranes have been increasingly utilized for Guided Bone Regeneration (GBR), as an alternative to non-resorbable synthetic membranes that require a second surgical intervention for removal. One of the most important characteristics of a resorbable barrier membrane is its mechanical integrity that is required for space maintenance and its tissue integration that plays a crucial role in wound healing and bone augmentation. This study compares a commercially available porcine-derived sugar-crosslinked collagen membrane with two non-crosslinked collagen barrier membranes. The material analysis provides an insight into the influence of manufacturing on the microstructure. In vivo subcutaneous implantation model provides further information on the host tissue reaction of the barrier membranes, as well as their tissue integration patterns that involve cellular infiltration, vascularization, and degradation. The obtained histochemical and immunohistochemical results over three time points (10, 30, and 60 days) showed that the tissue response to the sugar crosslinked collagen membrane involves inflammatory macrophages in a comparable manner to the macrophages observed in the surrounding tissue of the control collagen-based membranes, which were proven as biocompatible. The tissue reactions to the barrier membranes were additionally compared to wounds from a sham operation. Results suggest wound healing properties of all the investigated barrier membranes. However, the sugar-crosslinked membrane lacked in cellular infiltration and transmembraneous vascularization, providing an exclusive barrier function in GBR. Moreover, this membrane maintained a similar swelling ratio over examined timepoints, which suggests a very slow degradation pattern and supports its barrier function. Based on the study results, which showed biocompatibility of the sugar crosslinked membrane and its stability up to 60 days post-implantation, it can be concluded that this membrane may be suitable for application in GBR as a biomaterial with exclusive barrier functionality, similar to non-resorbable options.

scholarly journals Barrier membranes for guided bone regeneration

2020 ◽  
Vol 24 (2) ◽  
pp. 114-118
Author(s):  
A. A. Kulakov ◽  
V. A. Badalyan ◽  
Tursunbay K. Khamraev ◽  
A. S. Kasparov ◽  
V. A. Brutyan
Keyword(s):  
Bone Regeneration ◽  
English Language ◽  
Surgical Techniques ◽  
Guided Bone Regeneration ◽  
Barrier Membranes ◽  
Wire Frame ◽  
Literary Sources ◽  
Regeneration Procedure

The aim of this study was to review the possibilities of using the various types of membranes currently available and used in the guided bone regeneration procedure. Literary sources were analyzed, including English-language articles from the pubmed and elibrary information portals. For horizontal defects, it is most preferable to use resorbable membranes with various modifications of surgical techniques, while for vertical defects, the use of wire-frame non-reabsorbable membranes is most acceptable.

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