Study of the Factors Affecting Health-Related Quality of Life in Adolescents After Liver Transplantation

2009 ◽  
Vol 9 (5) ◽  
pp. 1179-1188 ◽  
Author(s):  
R. M. Taylor ◽  
L. S. Franck ◽  
F. Gibson ◽  
N. Donaldson ◽  
A. Dhawan
Author(s):  
Kisook Kim ◽  
Hyohyeon Yoon

The study aimed to identify and compare the factors affecting health-related quality of life (HRQoL) depending on the occupational status of cancer survivors. This study was a secondary data analysis from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2014 to 2018. Hierarchical multivariate linear regression was used to investigate the factors affecting the HRQoL of each group. Non-working cancer survivors had significantly lower HRQoL than working cancer survivors (p < 0.001). A hierarchical multiple regression model showed that demographic, health-related, and psychological characteristics explained 62.0% of non-working cancer survivors’ HRQoL (F = 4.29, p < 0.001). Among the input variables, health-related characteristics were the most influential factors (ΔR2 = 0.274, F = 9.84, p < 0.001). For working cancer survivors, health-related characteristics were the only variable that was statistically associated with HRQoL (F = 5.556, p < 0.001). It is important to enhance physical activities and manage the chronic disease to improve the HRQoL of working cancer survivors. Further, managing health-related characteristics, including depressive symptoms and suicidal ideation, is necessary for non-working cancer survivors. Regarding working survivors, psychological factors such as depressive symptoms and suicidal tendencies did not affect HRQoL. Therefore, an early and effective return to work program should be developed for the improvement of their HRQoL.


2007 ◽  
Vol 1 (4) ◽  
pp. 437-443 ◽  
Author(s):  
Jolie J. Gutteling ◽  
Robert A. de Man ◽  
Jan J. V. Busschbach ◽  
Anne-Sophie E. Darlington

Hepatology ◽  
2003 ◽  
Vol 38 ◽  
pp. 380-380 ◽  
Author(s):  
S SUNDARAM ◽  
K NEIGHBORS ◽  
L AMARUSO ◽  
J SINACORE ◽  
E ALONSO

2018 ◽  
Vol 32 (12) ◽  
pp. e13434 ◽  
Author(s):  
Marcin Krawczyk ◽  
Małgorzata Koźma ◽  
Agnieszka Szymańska ◽  
Katarzyna Leszko ◽  
Marta Przedniczek ◽  
...  

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1889-1894
Author(s):  
Setareh Dastyar Haghighi ◽  
Vandhita Nair ◽  
Vas Sonali Maria ◽  
Gopika K S ◽  
Divya Mol E C ◽  
...  

Alcohol induced cirrhosis prevalence has increased worldwide of late and has added markedly to the global burden of diseases. However, research involving quality of life as treatment outcome for alcoholic liver disease is limited. The primary objective of the study was to evaluate the health related quality of life and factors affecting it in alcoholic liver disease patients. Secondary objective was to analyze mental health status and prescription pattern in alcoholic liver disease patients. Patients, eligible to participate, were briefed regarding the purpose of the study and informed consent was obtained. Self-designed case report form and validated questionnaires were used to record information on physical, mental and emotional functioning of the patient. The study included 51 patients. It was found that majority had low quality of life scores with role limitation due to physical health (5.39 ± 16.9) domain being the most affected. It was also found that the symptom fatigue caused the most hindrance to patient’s daily activities (1.31± 1.20). Most of the patients reported having mild depression (50.98%). Prescription analysis showed that diuretics (74.50%) and drugs for hepatic encephalopathy were the most commonly used drugs. The present study found that alcoholic liver disease considerably impaired health related quality of life and identified the contributing factors as presence of complication, age, severity of disease and symptoms like fatigue and abdominal pain. Hence, evaluating factors affecting quality of life and prescription patterns help identify targets for novel treatment strategies.


2021 ◽  
Vol 15 (1) ◽  
pp. 196-203
Author(s):  
Larissa S. Santos-Lins ◽  
Inácio L.S. Aguiar ◽  
Liana Codes ◽  
Maria A. Evangelista ◽  
Alessandra de Oliveira Castro ◽  
...  

Background: Oral health is associated with Chronic Liver Disease (CLD) and may play a relevant role in oral (OHRQoL) and general health-related quality of life (HRQoL) among people with chronic liver disease (CLD). Objective: To explore the correlations between OHRQoL and HRQoL in pre- and post-liver transplantation (LT) patients. Methods: A cross-sectional study with 189 patients: 63 per group (pre-LT, post-LT, and without liver disease). The Oral Health Impact Profile-14 (OHIP-14), the 36-Item Short-Form Health Survey, and the Work Ability Index (WAI) were used to measure oral health-related quality of life, health-related quality of life, and work ability, respectively. Oral health was evaluated according to the World Health Organization criteria. The relationship between the OHIP-14 and independent variables was analysed by multiple linear regression. Results: Pre-LT group presented the highest OHIP-14 total mean score, followed by the post-LT group, compared to the group without liver disease (p=0.001). All HRQoL and WAI mean scores were lower in the pre-LT group than in the other groups (p≤0.013). In the pre-LT group, the OHIP-14 total mean score was negatively correlated with the Mental Health, Physical Functioning, and General Health mean scores (p=0.01) and negatively and significantly (p<0.05) associated with decayed teeth and with poor workability. In the post-TL group, OHRQOL of life was associated with decayed and missing teeth, lower educational level, and poor workability. Conclusion: Patients in the pre- and post-LT groups presented poorer OHRQoL compared to patients without liver disease. OHRQoL was strongly correlated with HRQoL in the pre-LT group.


2016 ◽  
Vol 20 (6) ◽  
pp. 738-746 ◽  
Author(s):  
J. Y. Yoo ◽  
Y. S. Kim ◽  
S. S. Kim ◽  
H. K. Lee ◽  
C. G. Park ◽  
...  

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