scholarly journals Assessment of Health-Related Quality of Life in Alcoholic Liver Disease Patients

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1889-1894
Author(s):  
Setareh Dastyar Haghighi ◽  
Vandhita Nair ◽  
Vas Sonali Maria ◽  
Gopika K S ◽  
Divya Mol E C ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Liver Disease ◽  
Alcoholic Liver Disease ◽  
Case Report Form ◽  
Health Related Quality ◽  
Mild Depression ◽  
Factors Affecting ◽  
Related Quality ◽  
Health Related

Alcohol induced cirrhosis prevalence has increased worldwide of late and has added markedly to the global burden of diseases. However, research involving quality of life as treatment outcome for alcoholic liver disease is limited. The primary objective of the study was to evaluate the health related quality of life and factors affecting it in alcoholic liver disease patients. Secondary objective was to analyze mental health status and prescription pattern in alcoholic liver disease patients. Patients, eligible to participate, were briefed regarding the purpose of the study and informed consent was obtained. Self-designed case report form and validated questionnaires were used to record information on physical, mental and emotional functioning of the patient. The study included 51 patients. It was found that majority had low quality of life scores with role limitation due to physical health (5.39 ± 16.9) domain being the most affected. It was also found that the symptom fatigue caused the most hindrance to patient’s daily activities (1.31± 1.20). Most of the patients reported having mild depression (50.98%). Prescription analysis showed that diuretics (74.50%) and drugs for hepatic encephalopathy were the most commonly used drugs. The present study found that alcoholic liver disease considerably impaired health related quality of life and identified the contributing factors as presence of complication, age, severity of disease and symptoms like fatigue and abdominal pain. Hence, evaluating factors affecting quality of life and prescription patterns help identify targets for novel treatment strategies.

scholarly journals Health-Related Quality of Life among Cancer Survivors Depending on the Occupational Status

2021 ◽  
Vol 18 (7) ◽  
pp. 3803
Author(s):  
Kisook Kim ◽  
Hyohyeon Yoon
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Cancer Survivors ◽  
Occupational Status ◽  
Influential Factors ◽  
Health Related Quality ◽  
Factors Affecting ◽  
Related Quality ◽  
Health Related

The study aimed to identify and compare the factors affecting health-related quality of life (HRQoL) depending on the occupational status of cancer survivors. This study was a secondary data analysis from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2014 to 2018. Hierarchical multivariate linear regression was used to investigate the factors affecting the HRQoL of each group. Non-working cancer survivors had significantly lower HRQoL than working cancer survivors (p < 0.001). A hierarchical multiple regression model showed that demographic, health-related, and psychological characteristics explained 62.0% of non-working cancer survivors’ HRQoL (F = 4.29, p < 0.001). Among the input variables, health-related characteristics were the most influential factors (ΔR2 = 0.274, F = 9.84, p < 0.001). For working cancer survivors, health-related characteristics were the only variable that was statistically associated with HRQoL (F = 5.556, p < 0.001). It is important to enhance physical activities and manage the chronic disease to improve the HRQoL of working cancer survivors. Further, managing health-related characteristics, including depressive symptoms and suicidal ideation, is necessary for non-working cancer survivors. Regarding working survivors, psychological factors such as depressive symptoms and suicidal tendencies did not affect HRQoL. Therefore, an early and effective return to work program should be developed for the improvement of their HRQoL.

Health-related quality of life in chronic liver disease: the impact of type and severity of disease

2001 ◽  
Vol 96 (7) ◽  
pp. 2199-2205 ◽  
Author(s):  
Zobair M Younossi ◽  
Navdeep Boparai ◽  
Lori Lyn Price ◽  
Michelle L Kiwi ◽  
Marilyn McCormick ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Chronic Liver ◽  
Health Related Quality ◽  
Severity Of Disease ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Mo1546 Health-Related Quality of Life and Health Utilities in Patients With Non-Alcoholic Fatty Liver Disease

2016 ◽  
Vol 150 (4) ◽  
pp. S1141
Author(s):  
Mehmet Sayiner ◽  
Maria Stepanova ◽  
Huong Pham ◽  
Bashir Noor ◽  
Mercedes Walters ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Health Related Quality ◽  
Alcoholic Fatty Liver ◽  
Related Quality ◽  
Health Related ◽  
Alcoholic Fatty Liver Disease

scholarly journals Poor Oral Health-Related Quality of Life in Pre- and Post-Liver Transplantation Patients

2021 ◽  
Vol 15 (1) ◽  
pp. 196-203
Author(s):  
Larissa S. Santos-Lins ◽  
Inácio L.S. Aguiar ◽  
Liana Codes ◽  
Maria A. Evangelista ◽  
Alessandra de Oliveira Castro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Liver Transplantation ◽  
Liver Disease ◽  
Oral Health ◽  
Work Ability ◽  
General Health ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Background: Oral health is associated with Chronic Liver Disease (CLD) and may play a relevant role in oral (OHRQoL) and general health-related quality of life (HRQoL) among people with chronic liver disease (CLD). Objective: To explore the correlations between OHRQoL and HRQoL in pre- and post-liver transplantation (LT) patients. Methods: A cross-sectional study with 189 patients: 63 per group (pre-LT, post-LT, and without liver disease). The Oral Health Impact Profile-14 (OHIP-14), the 36-Item Short-Form Health Survey, and the Work Ability Index (WAI) were used to measure oral health-related quality of life, health-related quality of life, and work ability, respectively. Oral health was evaluated according to the World Health Organization criteria. The relationship between the OHIP-14 and independent variables was analysed by multiple linear regression. Results: Pre-LT group presented the highest OHIP-14 total mean score, followed by the post-LT group, compared to the group without liver disease (p=0.001). All HRQoL and WAI mean scores were lower in the pre-LT group than in the other groups (p≤0.013). In the pre-LT group, the OHIP-14 total mean score was negatively correlated with the Mental Health, Physical Functioning, and General Health mean scores (p=0.01) and negatively and significantly (p<0.05) associated with decayed teeth and with poor workability. In the post-TL group, OHRQOL of life was associated with decayed and missing teeth, lower educational level, and poor workability. Conclusion: Patients in the pre- and post-LT groups presented poorer OHRQoL compared to patients without liver disease. OHRQoL was strongly correlated with HRQoL in the pre-LT group.

scholarly journals Symptom prevalence and quality of life of patients with end-stage liver disease: A systematic review and meta-analysis

2018 ◽  
Vol 33 (1) ◽  
pp. 24-36 ◽  
Author(s):  
Jen-Kuei Peng ◽  
Nilay Hepgul ◽  
Irene J Higginson ◽  
Wei Gao
Keyword(s):  
Quality Of Life ◽  
Liver Disease ◽  
Summary Score ◽  
Health Related Quality ◽  
End Stage Liver Disease ◽  
Related Quality ◽  
Health Related ◽  
Symptom Prevalence ◽  
End Stage

Background: End-stage liver disease is a common cause of morbidity and mortality worldwide, yet little is known about its symptomatology and impact on health-related quality of life. Aim: To describe symptom prevalence and health-related quality of life of patients with end-stage liver disease to improve care. Design: Systematic review. Data sources: We searched eight electronic databases from January 1980 to June 2018 for studies investigating symptom prevalence or health-related quality of life of adult patients with end-stage liver disease. No language restrictions were applied. Meta-analyses were performed where appropriate. Results: We included 80 studies: 35 assessing symptom prevalence, 41 assessing health-related quality of life, and 4 both. The instruments assessing symptoms varied across studies. The most frequently reported symptoms were as follows: pain (prevalence range 30%–79%), breathlessness (20%–88%), muscle cramps (56%–68%), sleep disturbance (insomnia 26%–77%, daytime sleepiness 29.5%–71%), and psychological symptoms (depression 4.5%–64%, anxiety 14%–45%). Erectile dysfunction was prevalent (53%–93%) in men. The health-related quality of life of patients with end-stage liver disease was significantly impaired when compared to healthy controls or patients with chronic liver disease. Compared with compensated cirrhosis, decompensation led to significant worsening of both components of the 36-Item Short Form Survey although to a larger degree for the Physical Component Summary score (decrease from average 6.4 (95% confidence interval: 4.0–8.8); p < 0.001) than for the Mental Component Summary score (4.5 (95% confidence interval: 2.4–6.6); p < 0.001). Conclusion: The symptom prevalence of patients with end-stage liver disease resembled that of patients with other advanced conditions. Given the diversity of symptoms and significantly impaired health-related quality of life, multidisciplinary approach and timely intervention are crucial.

Factors affecting the trajectory of health-related quality of life in COPD patients

2016 ◽  
Vol 20 (6) ◽  
pp. 738-746 ◽  
Author(s):  
J. Y. Yoo ◽  
Y. S. Kim ◽  
S. S. Kim ◽  
H. K. Lee ◽  
C. G. Park ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Related Quality ◽  
Factors Affecting ◽  
Copd Patients ◽  
Related Quality ◽  
Health Related
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