Mobilization Of Hepatic Vitamin A By Zinc Supplementation In Zinc Deficiency Associated With Protein-Energy Malnutrition

2009 ◽  
Vol 38 (8) ◽  
pp. 275-277
2019 ◽  
Vol 2 (1) ◽  
pp. 1-10
Author(s):  
Margherita Suppini Sumardi ◽  
Nurpudji A. Taslim ◽  
A. Yasmin Syauki

Luka bakar merupakan masalah kesehatan masyarakat yang paling sering ditemukan pada usia produktif. Data unit luka bakar rumah sakit di Indonesia menunjukkan terjadinya peningkatan mortalitas. Pada luka bakar berat terjadi hipermetabolisme dan proteolisis yang tinggi sehingga diperlukan terapi nutrisi yang tepat dan dini. Dilaporkan kasus seorang laki-laki, 18 tahun dengan keluhan nafsu makan melalui oral menurun dengan diagnosis severe protein energy malnutrition, luka bakar listrik 48% grade II-III. Terapi nutrisi yang diberikan adalah diet energi 3350 kkal melalui oral dan parenteral dengan komposisi protein: karbohidrat: lemak = 14,3%: 50%: 35,7%. Diet dimulai dengan 40% lalu 80% dan 100% dari total energi (hari ke-III). Kebutuhan protein 2,0 g/kg/hari dengan suplementasi parenteral glutamin (13,46 g/hari). Suplementasi mikronutrien berupa zink 40 mg/24 jam, ekstrak ikan gabus 480 g/hari, vitamin B1 4 mg/8 jam, vitamin C 500 mg/12 jam, vitamin A 10.000 IU/24 jam. Perbaikan balans nitrogen dari -7,7 menjadi +5,36. Albumin dan protein total mengalami perbaikan dari 2, 4 g/dl menjadi 3,5 g/dl dan 6,8 g/dl menjadi 6,8 g/dl. Penyembuhan luka terjadi dengan baik (inflamasi-repair dan remodeling) selama tiga puluh tiga hari masa perawatan. Kesimpulan: suplementasi glutamin dengan asupan tinggi protein dapat mempercepat penyembuhan luka, dan mencegah mortalitas pada pasien luka bakar berat.


2013 ◽  
Vol 6 ◽  
pp. 118-121
Author(s):  
Bhim Prasad Pulami ◽  
Surendra Katawal

Due to wide spread poverty, low income and non-availability of nutritious foods there are rampant of nutritional disorders such as protein energy malnutrition (PEM), anemia, vitamin-A deficiency, iodine deficiency disorder among preschool children in developing countries. Main purpose of the study is to formulate low cost supplementary weaning food from locally available raw materials. Based on the sensory evaluation, formula-I was preferred as a best sample (p<0.05). Chemical analysis of formula-I had been performed and found to be 2.02% moisture, 11.72% crude protein, 20.58% crude fat, 3.11% total ash, 2.69% crude fiber, 59.88% carbohydrate (by difference), 471 Kcal/100 g energy (calculated), 870.15 mg/100g vitamin A (âcarotene; calculated), 11.86mg/100g iron, 275mg/100g calcium, 23.55mg/100g ascorbic acid, 35.6μg/100g iodine and 55% water absorbing capacity. The costing revealed the retail product price per kg as NRs. 71.20. J. Food Sci. Technol. Nepal, Vol. 6 (118-121), 2010 DOI: http://dx.doi.org/10.3126/jfstn.v6i0.8273


Parasitology ◽  
2000 ◽  
Vol 121 (S1) ◽  
pp. S5-S22 ◽  
Author(s):  
L.S. STEPHENSON ◽  
M.C. LATHAM ◽  
E.A. OTTESEN

The four most important forms of malnutrition worldwide (protein-energy malnutrition, iron deficiency and anaemias (IDA), vitamin A deficiency (VAD), and iodine deficiency disorders (IDD)) are examined below in terms of their global and regional prevalences, the age and gender groups most affected, their clinical and public health consequences, and, especially, the recent progress in country and regional quantitation and control. Zinc deficiency, with its accompanying diminished host resistance and increased susceptibility to infections, is also reviewed. WHO estimates that malnutrition (underweight) was associated with over half of all child deaths in developing countries in 1995. The prevalence of stunting in developing countries is expected to decline from 36% in 1995 to 32·5% in 2000; the numbers of children affected (excluding China) are expected to decrease from 196·59millions to 181·92millions. Stunting affects 48% of children in South Central Asia, 48% in Eastern Africa, 38% in South Eastern Asia, and 13–24% in Latin America. IDA affects about 43% of women and 34% of men in developing countries and usually is most serious in pregnant women and children, though non-pregnant women, the elderly, and men in hookworm-endemic areas also comprise groups at risk. Clinical VAD affects at least 2·80million preschool children in over 60 countries, and subclinical VAD is considered a problem for at least 251millions; school-age children and pregnant women are also affected. Globally about 740million people are affected by goitre, and over two billions are considered at risk of IDD. However, mandatory salt iodisation in the last decade in many regions has decreased dramatically the percentage of the population at risk. Two recent major advances in understanding the global importance of malnutrition are (1) the data of 53 countries that links protein-energy malnutrition (assessed by underweight) directly to increased child mortality rates, and (2) the outcome in 6 of 8 large vitamin A supplementation trials showing decreases of 20–50% in child mortality.


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