STERILE PHARMACEUTICAL PREPARATIONS OF PROTEOLYTIC ENZYMES FOR CLINICAL USE IN DENTAL PRACTICE

1951 ◽  
Vol 3 (1) ◽  
pp. 756-766 ◽  
Author(s):  
Kenneth Bullock ◽  
J. K. Sen
Keyword(s):  
Proteolytic Enzymes ◽  
Pharmaceutical Preparations ◽  
Dental Practice ◽  
Clinical Use

Therapeutics

2020 ◽  
pp. 595-621
Keyword(s):  
Regulatory Agency ◽  
Adverse Reactions ◽  
Oral Anticoagulants ◽  
Information Service ◽  
Healthy Adults ◽  
Dental Practice ◽  
Clinical Use ◽  
Osteonecrosis Of The Jaws ◽  
Medicines Information ◽  
Local Contact

This chapter contains a brief guide to the clinical use of some of the more commonly used and useful drugs in hospital and general dental practice. Doses are for healthy adults. There is also information on prescribing guidelines and adverse reactions which may be encountered. The chapter includes local contact details for the Medicines Information Service as well as details on how to report adverse reactions to drugs to the Medicines and Healthcare products Regulatory Agency (MHRA). Contraindications of common drugs are outlined and updated information on oral anticoagulants and antiplatelets is included, as well as details on medication-related osteonecrosis of the jaws.

scholarly journals Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo

2011 ◽  
Vol 105 (05) ◽  
pp. 828-836 ◽  
Author(s):  
Thibaut Quillard ◽  
Kevin Croce ◽  
Farouc Jaffer ◽  
Ralph Weissleder ◽  
Peter Libby
Keyword(s):  
Cardiovascular Diseases ◽  
Protease Activity ◽  
Proteolytic Enzymes ◽  
Clinical Care ◽  
Clinical Use ◽  
Activity Detection ◽  
Cardiac Allografts ◽  
Large Families ◽  
Atherosclerosis Imaging

SummaryMacrophages contribute pivotally to cardiovascular diseases (CVD), notably to atherosclerosis. Imaging of macrophages in vivo could furnish new tools to advance evaluation of disease and therapies. Proteolytic enzymes serve as key effectors of many macrophage contributions to CVD. Therefore, intravital imaging of protease activity could aid evaluation of the progress and outcome of atherosclerosis, aortic aneurysm formation, or rejection of cardiac allografts. Among the large families of proteases, matrix metalloproteinases (MMPs) and cysteinyl cathepsins have garnered the most interest because of their participation in extra-cellular matrix remodelling. These considerations have spurred the development of dedicated imaging agents for protease activity detection. Activatable fluorescent probes, radiolabelled inhibitors, and nanoparticles are currently under exploration for this purpose. While some agents and technologies may soon see clinical use, others will require further refinement. Imaging of macrophages and protease activity should provide an important adjunct to understanding pathophysiology in vivo, evaluating the effects of interventions, and ultimately aiding clinical care.

Clinical use of antibiotics in dental practice

1998 ◽  
Vol 9 (4) ◽  
pp. 235-238 ◽  
Author(s):  
Daniel H Fine ◽  
Benjamin F Hammond ◽  
Walter J Loesche
Keyword(s):  
Dental Practice ◽  
Clinical Use

scholarly journals Comparative chemical study of MTA and portland cements

2007 ◽  
Vol 18 (1) ◽  
pp. 3-7 ◽  
Author(s):  
Marília Gerhardt de Oliveira ◽  
Cristina Braga Xavier ◽  
Flávio Fernando Demarco ◽  
Antônio Luis Barbosa Pinheiro ◽  
Aline Tempel Costa ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Portland Cement ◽  
Chemical Elements ◽  
Mineral Trioxide Aggregate ◽  
Chemical Study ◽  
Descriptive Statistics ◽  
Dental Practice ◽  
Clinical Use ◽  
Chemical Similarity ◽  
Scanning Electron

Portland cement has been analyzed and compared to mineral trioxide aggregate (MTA) because of their chemical similarity. The possibility of using this material as a less expensive alternative to MTA in dental practice should be considered. In view of this, the present study compared the components of a Portland cement (Votoran®) to two commercial brands of MTA (Pro-Root™ and MTA-Angelus®). Twelve specimens of each material were fabricated and examined by scanning electron microscopy (SEM) with energy dispersive spectroscopy (EDS) to obtain their percentage of chemical elements. The means of the chemical elements found in each material was compared by descriptive statistics. Bismuth was present only in MTA cements to provide radiopacity. In conclusion, the tested cements have similar components, which supports, as far as composition is concerned, the possible clinical use of Portland as an option to MTA.

Research in General Dental Practice: Evaluation of the Clinical Use of a New Composite System by General Dental Practitioners

2002 ◽  
Vol os9 (2) ◽  
pp. 57-61 ◽  
Author(s):  
Raymond W Li ◽  
Arthur W Pang ◽  
Frank Sun
Keyword(s):  
Composite System ◽  
Dental Practice ◽  
Clinical Use ◽  
Matrix System ◽  
Aesthetic Outcome ◽  
Selection Procedures ◽  
Handling Characteristics ◽  
Dental Practitioners ◽  
Analogue Scales ◽  
Shade Selection

Introduction The purpose of the study was to evaluate a recently introduced aesthetic restorative system in respect of: • Presentation and organisation of the package. • Its handling characteristics. • Its polishability. • Shade selection procedures and aesthetic outcome. Material and method The material, Esthet.X Micro Matrix system (Dents-ply), was evaluated by general dental practitioners from a clinical research group known as PEER (Product and Equipment Evaluation and Research). The evaluators were asked to use the material, following manufacturer's instructions, in a variety of cases. A questionnaire was designed specifically for this study and the questions were directed to both the dentists and their dental nurses. The results were analysed statistically and represented in visual analogue scales. Result The material was found to be useful and generally well received. Its use was thought to be technique sensitive but good to excellent results can be achieved. Areas where the evaluators thought the product could be improved were also discussed.

scholarly journals Basic and Clinical Pharmacology of Glucocorticosteroids

2013 ◽  
Vol 60 (1) ◽  
pp. 25-32 ◽  
Author(s):  
Daniel E. Becker
Keyword(s):  
Clinical Pharmacology ◽  
Adrenal Cortex ◽  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Dental Practice ◽  
Physiological Effects ◽  
Clinical Use ◽  
Basic Functions ◽  
Anti Inflammatory

Abstract Glucocorticosteroids are a product of the adrenal cortex and perform a staggering number of physiological effects essential for life. Their clinical use is largely predicated on their anti-inflammatory and immunosuppressive properties, but they also have notable efficacy in the prophylaxis of postoperative nausea and vomiting. This article reviews the basic functions of glucocorticoids and their clinical use in dental practice.

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