scholarly journals Differences in platelet‐rich plasma composition influence bone healing

Author(s):  
Faez Saleh Al‐Hamed ◽  
Lina Abu‐Nada ◽  
Rania Rodan ◽  
Stylianos Sarrigiannidis ◽  
Jose Luis Ramirez‐Garcialuna ◽  
...  
Bone ◽  
2009 ◽  
Vol 45 (2) ◽  
pp. 339-345 ◽  
Author(s):  
Maria Nagata ◽  
Michel Messora ◽  
Roberta Okamoto ◽  
Natália Campos ◽  
Natália Pola ◽  
...  

2019 ◽  
Vol 14 (1) ◽  
pp. 311-317
Author(s):  
Wei Liu ◽  
Ben Chen ◽  
Youyang Zheng ◽  
Yuehua Shi ◽  
Zhuojin Shi

AbstractPlatelet-rich plasma (PRP) has been shown to be a beneficial growth factor for bone tissue healing and is used in implantology. The aim of this study was to investigate the effects of PRP on bone defects in rabbits. Twenty rabbits were used to establish the implant bone defect model in this study. An intrabony defect (5mm × 5mm × 3mm) was created in alveolar bone in the lower jar of each rabbit. The wound was treated with PRP. The expression of platelet-derived growth factor BB (PDGFBB) was assessed by enzyme-linked immunosorbent assay (ELISA). Focal adhesion kinase (FAK) and related phosphatidylinositol 3-kinase (PI3K)/AKT (protein kinase B) levels were measured by Western blot. The results show that PRP could significantly improve the bone healing process when compared with control, and 10% PRP could markedly increase fibroblast proliferation 48-h post treatment. PDGFBB was higher in the PRP group than that in the control group. PRP treatment also could elevate the phosphorylation of FAK and PI3K/AKT, although the inhibitor of PDGFR could reverse this trend. These results suggest that PRP treatment improves the bone healing process through the FAK/PI3K/AKT pathway.


2012 ◽  
Vol 23 (5) ◽  
pp. 1318-1323 ◽  
Author(s):  
Gregory Faratzis ◽  
Minas Leventis ◽  
Evanthia Chrysomali ◽  
Lubna Khaldi ◽  
Areti Eleftheriadis ◽  
...  

2017 ◽  
Vol 58 (9) ◽  
pp. 551-556 ◽  
Author(s):  
V Galanis ◽  
A Fiska ◽  
S Kapetanakis ◽  
K Kazakos ◽  
T Demetriou

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 962-966
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy

Platelet Rich Plasma(PRP), serving as a vehicle and wellspring of development factors, is a homologous plasma formulation with congregated platelets broadly studied for its applications as a scaffold in cell-based intervention and tissue engineering. The aim of the study was to assess the awareness about regenerative therapy with platelet Rich Plasma (PRP) among dental students. A cross-sectional study was done with a self-administered questionnaire with ten questions circulated among 100 dental students. The questionnaire assessed the awareness about PRP regenerative therapy in surgical applications, their uses, periodontal applications, surgical applications and bone healing. The responses were recorded and . 82% of the respondents were aware of surgical applications of PRP regenerative therapy. 73% were aware of uses of regenerative therapy. 77% of the respondents were aware of periodontal applications of PRP regenerative therapy. 75% of the respondents were aware of surgical implant applications of PRP regenerative therapy. 78 % of the respondents were aware of bone healing properties of PRP regenerative therapy. The awareness about the use of PRP regenerative therapy in dentalapplications is high among dental students. Increased awareness programs and sensitization and continuing dental education programs along with more significant importance to the curricular modifications, can further enhance knowledge and awareness about PRP regenerative therapy.


2018 ◽  
Vol 7 (9) ◽  
pp. 342-347
Author(s):  
Jonathan Harris Ricardo ◽  
◽  
María Osorio Daguer ◽  
Natalia Fortich Mesa ◽  
◽  
...  

Orthopedics ◽  
2012 ◽  
Vol 35 (4) ◽  
pp. e520-e525 ◽  
Author(s):  
Wenliang Zhai ◽  
Nan Wang ◽  
Zhi Qi ◽  
Quan Gao ◽  
Liren Yi

Sign in / Sign up

Export Citation Format

Share Document