scholarly journals Allogeneic islet transplantation with monitoring of islet‐specific cellular autoimmunity in a Japanese patient with type 1 diabetes: a case report

Author(s):  
Daisuke Chujo ◽  
Toshiaki Kurokawa ◽  
Akitsu Kawabe ◽  
Nobuyuki Takahashi ◽  
Fuyuki Inagaki ◽  
...  
2015 ◽  
Vol 54 (18) ◽  
pp. 2361-2365 ◽  
Author(s):  
Nobumasa Ohara ◽  
Masanori Kaneko ◽  
Toshio Yano ◽  
Naoko Sato ◽  
Hiroyuki Usuda ◽  
...  

2018 ◽  
Author(s):  
A Emile J Hendriks ◽  
Ross L Ewen ◽  
Yoke Sin Hoh ◽  
Nazia Bhatti ◽  
Rachel M Williams ◽  
...  

2019 ◽  
Author(s):  
Rolly Junior Louzolo-Kimbembe ◽  
Ghizlane El Mghari ◽  
Nawal El Ansari

Author(s):  
Sandrine Lablanche ◽  
Sophie Borot ◽  
Anne Wojtusciszyn ◽  
Kristina Skaare ◽  
Alfred Penfornis ◽  
...  

2020 ◽  
Vol 11 (1) ◽  
pp. 17
Author(s):  
Yousef Al Zoubi ◽  
Bashair M. Mussa ◽  
Ankita Srivastava ◽  
Abdul Khader Mohammed ◽  
Elamin Abdelgadir ◽  
...  

The recurrence of hypoglycemic episodes leads to attenuation of the normal counter-regulatory mechanisms that are controlled by the hypothalamus, which results in hypoglycemia unawareness (HU). In this case report, we described for the first time the differential expression of TNF-α, IL-1β, IL-6, and IFN-γ in a blood sample that was taken from a 27-year-old patient with type 1 diabetes mellitus (T1DM) who was diagnosed with HU. The anti-diabetic regimen is currently based on insulin injection, but the patient is planning to start the use of an insulin pump to have better control of glucose levels. Our results showed a trend toward an increase in the expression of IL-1β, IL-6, and IFN-γ in T1DM patient with HU. However, the mRNA level of TNF-α showed a significant decrease. These observations suggest that systemic inflammation could be an underlying cause of HU.


2013 ◽  
Vol 100 (2) ◽  
pp. e34-e38 ◽  
Author(s):  
Koh Yamashita ◽  
Yuka Sato ◽  
Kenichi Seki ◽  
Junpei Asano ◽  
Yoshiko Funase ◽  
...  

2019 ◽  
Vol 58 (5) ◽  
pp. 675-678 ◽  
Author(s):  
Jun-ya Hironaka ◽  
Seiichi Kitahama ◽  
Hiroyuki Sato ◽  
Maki Inoue ◽  
Tetsuya Takahashi ◽  
...  

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