The effectiveness of in‐office dental bleaching with and without sonic activation: A randomized, split‐mouth, double‐blind clinical trial

Background:More than half of the patients attending emergency centers need analgesics. Injectable analgesics are currently the most common pain control strategy, but entail complications. Fentanyl is one of the most commonly used pain-relief opiates available in various forms.Objective:The present study aims to compare analgesic effects of nebulized against intravenous fentanyl for controlling pain due to limb fracture.Method:The present double-blind clinical trial recruited 213 patients presenting with fractured limbs to emergency departments. The first group of patients received 1 micg/kg of intravenous fentanyl citrate from a solution of 50 micg/ml and 5 ml of normal saline in nebulized form (group A), and the second group intravenously received 5 ml of normal saline and 4 micg/kg of 50 micg/ml solution of fentanyl citrate in nebulized form, whose volume reached 5 ml with the addition of normal saline (group B). Then, pain level was frequently measured and compared in the two groups for 20 minutes.Results:The results obtained showed reduced pain level in both the groups. However, point-by-point comparison of pain in the two groups revealed significantly greater pain reduction in intravenous fentanyl group (P<0.001). The need for adjuvant pain relief medication was 8.3% in intravenous fentanyl group and 24% in nebulized fentanyl group, with a significant difference between the two groups (P=0.002).Conclusion:According to the results, although nebulized fentanyl is effective in controlling pain due to limb fracture, it was less effective than intravenous type, and unable to control pain in many cases.

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The Correlation Between Decreased Ornithine Level and Alleviation of Rheumatoid Arthritis Patients Assessed by a Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Sinomenine

Engineering ◽

10.1016/j.eng.2021.04.014 ◽

2021 ◽

Author(s):

Ying Shi ◽

Hu-Dan Pan ◽

Jian-Lin Wu ◽

Qing-Hua Zou ◽

Xin-Yi Xie ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Clinical Trial ◽

Double Blind ◽

Double Blind Clinical Trial

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Publisher Correction to: BRAINSTORMING: A study protocol for a randomised double-blind clinical trial to assess the impact of concurrent brain stimulation (tDCS) and working memory training on cognitive performance in Acquired Brain Injury (ABI)

BMC Psychology ◽

10.1186/s40359-021-00516-7 ◽

2021 ◽

Vol 9 (1) ◽

Author(s):

Sara Assecondi ◽

Rong Hu ◽

Gail Eskes ◽

Michelle Read ◽

Chris Griffiths ◽

...

Keyword(s):

Clinical Trial ◽

Working Memory ◽

Brain Injury ◽

Cognitive Performance ◽

Acquired Brain Injury ◽

Working Memory Training ◽

Memory Training ◽

Double Blind ◽

Double Blind Clinical Trial ◽

The Impact

Following publication of the original article [1], the authors flagged that the article had published with the Acknowledgements erroneously excluded from the declarations at the end of the article.

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