One-Year Change in the Japanese Version of the Montreal Cognitive Assessment Performance and Related Predictors in Community-Dwelling Older Adults

Abstract Background Growth differentiation factor 15 (GDF15) has been associated with several age-related disorders, but its associations with functional abilities in community-dwelling older adults are not well studied. Methods The study was a secondary analysis on 1096 community-dwelling older adults (aged 69 to 94 years) recruited from the Multidomain Alzheimer’s Preventive Trial. Plasma GDF15 was measured one year after participants’ enrolment. Annual data of physical performance (grip strength and short physical performance battery [SPPB]) and global cognitive functions (mini-mental state examination [MMSE] and a composite cognitive score) were measured for four years. Adjusted mixed-effects linear models were performed for cross-sectional and longitudinal association analyses. Results A higher GDF15 was cross-sectionally associated with a weaker grip strength (β = -1.1E-03, 95%CI [-2.0E-03, -1.5E-04]), a lower SPPB score (β = -3.1E-04, 95%CI [-5.4E-04, -9.0E-05]) and worse cognitive functions (β = -2.4E-04, 95%CI [-3.3E-04, -1.6E-04] for composite cognitive score; β = -4.0E-04, 95%CI [-6.4E-04, -1.6E-04] for MMSE). Participants with higher GDF15 demonstrated greater longitudinal declines in SPPB (β = -1.0E-04, 95%CI [-1.7E-04, -2.0E-05]) and composite cognitive score (β = -2.0E-05, 95%CI [-4.0E-05, -3.6E-06]). The optimal initial GDF15 cutoff values for identifying participants with minimal clinically significant decline after one year were 2189 pg/mL for SPPB (AUC: 0.580) and 2330 pg/mL for composite cognitive score (AUC: 0.587). Conclusions Plasma GDF15 is cross-sectionally and longitudinally associated with lower-limb physical performance and global cognitive function in older adults. Circulating GDF15 alone has limited capacity of discriminating older adults who will develop clinically significant functional declines.

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Can Virtual Assistants Perform Cognitive Assessment in Older Adults? A Review

Medicina ◽

10.3390/medicina57121310 ◽

2021 ◽

Vol 57 (12) ◽

pp. 1310

Author(s):

Carmen Moret-Tatay ◽

Isabel Iborra-Marmolejo ◽

María José Jorques-Infante ◽

José Vicente Esteve-Rodrigo ◽

Carla H. A. Schwanke ◽

...

Keyword(s):

Older Adults ◽

Cognitive Impairment ◽

Language Processing ◽

Cognitive Assessment ◽

Chronic Conditions ◽

Community Dwelling ◽

Screening Process ◽

Digital Devices ◽

The Given ◽

Community Dwelling Older Adults

Community-dwelling older adults have raised the scientific community’s interest during the COVID-19 era as their chronic conditions might be aggravated by the consequences of confinement. Digital devices in this field to monitor cognitive impairment are an emerging reality of an innovative nature. However, some groups may not have benefited from these developments as much as, for example, younger people. The aim of this manuscript is to carry out a review on the development of digital devices, and specifically virtual assistants, for the detection of cognitive impairment in older adults. After a screening process, eight studies were found under the given criteria, and this number was even smaller for those using virtual assistants. Given the opportunities offered by virtual assistants through techniques such as natural language processing, it seems imperative to take advantage of this opportunity for groups such as older adults.

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Validation of one-year reliable change in the RBANS for community-dwelling older adults with amnestic mild cognitive impairment

The Clinical Neuropsychologist ◽

10.1080/13854046.2020.1807058 ◽

2020 ◽

pp. 1-24

Author(s):

Dustin B. Hammers ◽

Kayla R. Suhrie ◽

Sariah M. Porter ◽

Ava M. Dixon ◽

Kevin Duff

Keyword(s):

Older Adults ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Amnestic Mild Cognitive Impairment ◽

Community Dwelling ◽

Reliable Change ◽

One Year ◽

Community Dwelling Older Adults

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Risk factors for future falls among community-dwelling older adults without a fall in the previous year: A prospective one-year longitudinal study

Archives of Gerontology and Geriatrics ◽

10.1016/j.archger.2020.104161 ◽

2020 ◽

Vol 91 ◽

pp. 104161 ◽

Cited By ~ 1

Author(s):

Jaqueline Mello Porto ◽

Natália Camargo Rodrigues Iosimuta ◽

Renato Campos Freire Júnior ◽

Roberta de Matos Brunelli Braghin ◽

Érika Leitner ◽

...

Keyword(s):

Risk Factors ◽

Older Adults ◽

Longitudinal Study ◽

Community Dwelling ◽

One Year ◽

Community Dwelling Older Adults

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Association Between Public Transportation Use and Loneliness Among Urban Elderly People Who Stop Driving

Gerontology and Geriatric Medicine ◽

10.1177/2333721419851293 ◽

2019 ◽

Vol 5 ◽

pp. 233372141985129 ◽

Cited By ~ 1

Author(s):

Naoka Matsuda ◽

Shunsuke Murata ◽

Kohtaroh Torizawa ◽

Tsunenori Isa ◽

Aoi Ebina ◽

...

Keyword(s):

Older Adults ◽

Public Transportation ◽

Multiple Linear Regression Model ◽

Japanese Version ◽

Cross Sectional Study ◽

Community Dwelling ◽

Urban Elderly ◽

Cross Sectional ◽

Group A ◽

Community Dwelling Older Adults

Aim: To examine the association between public transportation use and loneliness in urban elderly who stop driving. Methods: In this cross-sectional study, we assessed 31 community-dwelling older adults who had stopped driving. Public transportation use was assessed by using frequency and divided into two groups. The users group was participants who used public transportation more than once a week and the nonusers group was participants who used public transportation less than once a week. Loneliness was measured using the Japanese version of the UCLA Loneliness Scale version 3 (UCLA.LS.ver3), with a higher score indicating greater loneliness. The independent t test was used to compare the UCLA.LS.ver3 scores between users and nonusers group. A multiple linear regression model was used with the UCLA.LS.ver3 score as the objective variable and public transportation use as the explanatory variable. Results: The UCLA.LS.ver3 score was significantly higher in the nonusers group than in the users group (nonusers group: 12.7 ± 1.9; users group: 10.1 ± 2.9, p = .017). After adjustments, public transportation use was significantly associated with lower loneliness (β = −2.55, p = .029). Conclusion: Public transportation use might have important role to prevent loneliness in older adults who stop driving.

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Gender differences in health service use for mental health reasons in community dwelling older adults with suicidal ideation

International Psychogeriatrics ◽

10.1017/s1041610212001895 ◽

2012 ◽

Vol 25 (3) ◽

pp. 374-381 ◽

Cited By ~ 19

Author(s):

Helen-Maria Vasiliadis ◽

Sarah Gagné ◽

Natalia Jozwiak ◽

Michel Préville

Keyword(s):

Mental Health ◽

Older Adults ◽

Suicidal Ideation ◽

Service Use ◽

Community Dwelling ◽

Symptoms Of Depression ◽

Antidepressant Use ◽

One Year ◽

Promotion Campaigns ◽

Community Dwelling Older Adults

ABSTRACTBackground: To ascertain gender-specific determinants of antidepressant and mental health (MH) service use associated with suicidal ideation.Methods: Data used in this study came from the ESA (Enquête sur la Santé des Aînés) survey carried out in 2005–2008 on a large sample of community-dwelling older adults (n = 2,004). Multivariate logistic regression analyses were carried out.Results: The two-year prevalence of suicidal ideation was 8.4% and 20.3% had persistent suicidal thoughts at one-year follow-up. In males, the prevalence of antidepressant and MH service use in respondents with suicidal ideation reached 32.2% and 48.9%, respectively. In females, the corresponding rates were 42.6% and 65.6%. Males were less likely to consult MH services than females when their MH was judged poorly. Male respondents with higher income and education were less likely to use antidepressant and MH services. However, males using benzodiazepines were more likely than females to be dispensed an antidepressant. Among respondents with suicidal ideation, gender was not associated with service use. Younger age, however, was associated with antidepressant use.Conclusions: Increased promotion campaigns sensitizing men to the prodromal symptoms of depression and the need to foster access to MH care when the disorder is manageable may be needed.

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