Safer Prescribing for Hospitalized Older Adults with an Electronic Health Records‐Based Prescribing Context

2020 ◽  
Vol 68 (9) ◽  
pp. 2123-2127 ◽  
Author(s):  
Kathleen Drago ◽  
Jackie Sharpe ◽  
Bryanna De Lima ◽  
Abdulaziz Alhomod ◽  
Elizabeth Eckstrom
2020 ◽  
Vol 68 (5) ◽  
pp. 1078-1082 ◽  
Author(s):  
Vanessa Ramirez‐Zohfeld ◽  
Anne Seltzer ◽  
Linda Xiong ◽  
Lucy Morse ◽  
Lee A. Lindquist

2019 ◽  
Vol 26 (8-9) ◽  
pp. 787-795 ◽  
Author(s):  
Tao Chen ◽  
Mark Dredze ◽  
Jonathan P Weiner ◽  
Hadi Kharrazi

Abstract Objective Geriatric syndromes such as functional disability and lack of social support are often not encoded in electronic health records (EHRs), thus obscuring the identification of vulnerable older adults in need of additional medical and social services. In this study, we automatically identify vulnerable older adult patients with geriatric syndrome based on clinical notes extracted from an EHR system, and demonstrate how contextual information can improve the process. Materials and Methods We propose a novel end-to-end neural architecture to identify sentences that contain geriatric syndromes. Our model learns a representation of the sentence and augments it with contextual information: surrounding sentences, the entire clinical document, and the diagnosis codes associated with the document. We trained our system on annotated notes from 85 patients, tuned the model on another 50 patients, and evaluated its performance on the rest, 50 patients. Results Contextual information improved classification, with the most effective context coming from the surrounding sentences. At sentence level, our best performing model achieved a micro-F1 of 0.605, significantly outperforming context-free baselines. At patient level, our best model achieved a micro-F1 of 0.843. Discussion Our solution can be used to expand the identification of vulnerable older adults with geriatric syndromes. Since functional and social factors are often not captured by diagnosis codes in EHRs, the automatic identification of the geriatric syndrome can reduce disparities by ensuring consistent care across the older adult population. Conclusion EHR free-text can be used to identify vulnerable older adults with a range of geriatric syndromes.


2018 ◽  
Vol 47 (4) ◽  
pp. 564-569 ◽  
Author(s):  
Daniel Stow ◽  
Fiona E Matthews ◽  
Stephen Barclay ◽  
Steve Iliffe ◽  
Andrew Clegg ◽  
...  

2018 ◽  
Vol 72 (3) ◽  
pp. 185-192 ◽  
Author(s):  
Carolina Ibarra-Castillo ◽  
Marina Guisado-Clavero ◽  
Concepció Violan-Fors ◽  
Mariona Pons-Vigués ◽  
Tomàs López-Jiménez ◽  
...  

BackgroundSeveral studies have analysed the characteristics of multimorbidity patterns but none have evaluated the relationship with survival. The purpose of this study was to compare survival across older adults with different chronic multimorbidity patterns (CMPs).MethodsProspective longitudinal observational study using electronic health records for 190 108 people aged ≥65 years in Barcelona, Spain (2009–2014). CMPs were identified by cluster analysis. Mortality rates were estimated using the Catalan population structure and individual time at risk. Survival according to CMP (Cox regression) was analysed using hazard ratios (HRs) and 95% confidence intervals (CIs) with stratification by sex and age group (65–79, 80–94) and adjustment for age at onset, deprivation index, number of chronic conditions and invoiced drugs.ResultsThe highest mortality rates were observed in men, adults aged 80–94 years, socially disadvantaged quintiles and people prescribed more drugs and with fewer conditions. Using the musculoskeletal pattern as the reference category, men with the digestive-respiratory pattern had a higher risk of death, with adjusted HRs of 6.16 (95% CI 5.37 to 7.06) in the 65–79 age group and 2.62 (95% CI 2.31 to 2.97) in the 80–94 age group. In women, the cardiovascular pattern was associated with the highest risk, with adjusted HRs of 6.34 (95% CI 5.28 to 7.61) in the 65–79 age group and 3.05 (95% CI 2.73 to 3.41) in the 80–94 age group. These patterns were also associated with the highest mortality rates.ConclusionsMortality and survival vary according to CMPs in older adults stratified by sex and age. Our findings are useful for guiding the design and implementation of clinical management strategies.


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