Association between periodontal inflammation and serum lipid profile in a healthy population: A cross‐sectional study

Data about lipoprotein changes and their link with cardiovascular disease and atherosclerosis in systemic sclerosis (SSc) are still challenging. We aimed to evaluate serum lipid profile of patients with SSc and to identify potential relation with different disease specific characteristics (clinical, serological, inflammatory tests) in a cross-sectional study. Standard assessments comprised SSc-related parameters (disease subtype, clinical spectrum, immunological tests) and lipid metabolism (total cholesterol and fractions, triglycerides). Impaired lipid profile (low serum HDL- and high LDL-cholesterol, increased serum triglycerides, slightly modification in total cholesterol level) significantly correlated with diffuse SSc, activity (EUSTAR) and severity (MEDSGER), as well as seropositivity for specific antibodies (anti-centromere and anti-topoisomerase 1). The dyslipidemic profile might represent a pathobiological pathway for atherosclerosis in SSc.

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Dysregulated serum lipid profile and its correlation to disease activity in young female adults diagnosed with systemic lupus erythematosus: a cross-sectional study

Lipids in Health and Disease ◽

10.1186/s12944-020-01232-8 ◽

2020 ◽

Vol 19 (1) ◽

Cited By ~ 1

Author(s):

Bo Zhou ◽

Yulong Xia ◽

Jianqing She

Keyword(s):

Systemic Lupus Erythematosus ◽

Disease Activity ◽

Lipid Profile ◽

Lupus Erythematosus ◽

Serum Lipid ◽

Cross Sectional Study ◽

Young Female ◽

Sectional Study ◽

Systemic Lupus ◽

Cross Sectional

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Association of Hypertensive Retinopathy with different serum lipid parameters in patients of Essential Hypertension: A Hospital Based Study

Journal of Nobel Medical College ◽

10.3126/jonmc.v7i2.22308 ◽

2018 ◽

Vol 7 (2) ◽

pp. 50-57

Author(s):

Bishwa Nath Adhikari ◽

Pramod Sharma Gautam ◽

Binod Bekoju ◽

Sadhana Basnet ◽

Himlal Bhandari

Keyword(s):

Essential Hypertension ◽

Lipid Profile ◽

Serum Lipid ◽

Cross Sectional Study ◽

Serum Lipid Profile ◽

Hypertensive Retinopathy ◽

Cross Sectional ◽

Hypertensive Patients ◽

Medical College ◽

Department Of Ophthalmology

Introduction: Abnormalities in serum lipid and lipoprotein levels are recognized as major modifiable risk factors for cardiovascular disease and essential hypertension and retinopathy. So this study was conducted to evaluate the role of dyslipidemia on development of retinopathy in hypertensive patients and to establish the association of parameters of serum lipid profile with hypertensive retinopathy. Materials and Methods: A cross-sectional study was conducted in Ophthalmology Department among 135 patients in Nobel Medical College and Teaching Hospital (NoMCTH), Biratnagar who were diagnosed with essential hypertension. Patients having diabetes mellitus, myopia, hazy ocular media and other posterior segment disorders were excluded from the study. The detailed ophthalmic examination was carried out in department of ophthalmology, NoMCTH, Biratnagar and all the study population were investigated for fasting serum lipid profile. Result: Out of 135 patients with essential hypertension, 65.44% had retinopathy and remaining had no signs of retinopathy. Mean age of patients were 60.24 (±15.14) years. Although no gender preponderance was found with retinopathy but this study showed that hypertensive retinopathy increases significantly with increase in age and its incidence increases after the age of 60 years. Conclusion: The duration of hypertension was found to be strongly associated with development of hypertensive retinopathy. The increase in all the lipid profile parameters (Serum TG, TC, and LDL and LDL:HDL) and the obesity were found to be strongly associated with retinopathy in hypertensive patients.

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