scholarly journals Detection of upper extremity deep vein thrombosis by magnetic resonance non‐contrast thrombus imaging

2021 ◽  
Author(s):  
Lisette F. van Dam ◽  
Charlotte E.A. Dronkers ◽  
Gargi Gautam ◽  
Åsa Eckerbom ◽  
Waleed Ghanima ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Magnetic Resonance ◽  
Upper Extremity ◽  
Vein Thrombosis ◽  
Thrombus Imaging ◽  
Deep Vein

Diagnosing upper extremity deep vein thrombosis with non-contrast-enhanced Magnetic Resonance Direct Thrombus Imaging: A pilot study

2018 ◽  
Vol 163 ◽  
pp. 47-50 ◽  
Author(s):  
C.E.A. Dronkers ◽  
F.A. Klok ◽  
G.R. van Haren ◽  
J. Gleditsch ◽  
E. Westerlund ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Pilot Study ◽  
Magnetic Resonance ◽  
Upper Extremity ◽  
Vein Thrombosis ◽  
Thrombus Imaging ◽  
Contrast Enhanced ◽  
Deep Vein

Magnetic resonance direct thrombus imaging differentiates acute recurrent ipsilateral deep vein thrombosis from residual thrombosis

Blood ◽  
2014 ◽  
Vol 124 (4) ◽  
pp. 623-627 ◽  
Author(s):  
Melanie Tan ◽  
Gerben C. Mol ◽  
Cornelis J. van Rooden ◽  
Frederikus A. Klok ◽  
Robin E. Westerbeek ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Magnetic Resonance ◽  
Vein Thrombosis ◽  
Thrombus Imaging ◽  
Key Points ◽  
Diagnostic Management ◽  
Deep Vein

Key Points Diagnostic management of ipsilateral recurrent DVT of the leg is complicated because residual DVT is common and mimics acute DVT on CUS. MRDTI is able to reproducibly distinguish acute ipsilateral recurrent DVT from 6-month-old chronic residual thrombi in the leg veins.

Magnetic resonance direct thrombus imaging at 3T field strength in patients with lower limb deep vein thrombosis: a feasibility study

2006 ◽  
Vol 61 (3) ◽  
pp. 282-286 ◽  
Author(s):  
S.A. Schmitz ◽  
D.P. O'Regan ◽  
D. Gibson ◽  
C. Cunningham ◽  
J. Fitzpatrick ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Magnetic Resonance ◽  
Field Strength ◽  
Feasibility Study ◽  
Lower Limb ◽  
Vein Thrombosis ◽  
Thrombus Imaging ◽  
Deep Vein ◽  
Limb Deep Vein Thrombosis

scholarly journals Combined MR direct thrombus imaging and non-contrast magnetic resonance venography reveal the evolution of deep vein thrombosis: a feasibility study

2016 ◽  
Vol 27 (6) ◽  
pp. 2326-2332 ◽  
Author(s):  
I. A. Mendichovszky ◽  
A. N. Priest ◽  
D. J. Bowden ◽  
S. Hunter ◽  
I. Joubert ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Magnetic Resonance ◽  
Feasibility Study ◽  
Magnetic Resonance Venography ◽  
Vein Thrombosis ◽  
Thrombus Imaging ◽  
Contrast Magnetic Resonance ◽  
Deep Vein

scholarly journals Magnetic resonance direct thrombus imaging of the evolution of acute deep vein thrombosis of the leg

2008 ◽  
Vol 6 (7) ◽  
pp. 1087-1092 ◽  
Author(s):  
R. E. WESTERBEEK ◽  
C. J. VAN ROODEN ◽  
M. TAN ◽  
A. P. G. VAN GILS ◽  
S. KOK ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Magnetic Resonance ◽  
Vein Thrombosis ◽  
Thrombus Imaging ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein

Accuracy of Magnetic Resonance Direct Thrombus Imaging (MRDTI) As a Novel Tool in the Diagnosis of Acute Ipsilateral Recurrent Deep Vein Thrombosis

Blood ◽  
2012 ◽  
Vol 120 (21) ◽  
pp. 395-395
Author(s):  
Melanie Tan ◽  
Gerben C Mol ◽  
Marcel A Van de Ree ◽  
Cornelis J Van Rooden ◽  
Robin E Westerbeek ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Magnetic Resonance ◽  
Ultrasound Examination ◽  
Kappa Statistics ◽  
Acute Thrombosis ◽  
Vein Thrombosis ◽  
Thrombus Imaging ◽  
Recurrent Deep Vein Thrombosis ◽  
Deep Vein ◽  
D Dimer

Abstract Abstract 395 Background Accurate diagnostic assessment of suspected acute ipsilateral recurrent deep vein thrombosis (DVT) is of high clinical importance, however discriminating residual thrombosis from acute recurrent DVT may be challenging. It is known that in 32% of the patients with a suspected acute ipsilateral recurrent DVT the ultrasound examination are non-conclusive. Despite this, patients were treated with indefinite anticoagulant therapy, indicating overtreatment in this group of patients (Tan M et al. J Thromb Haemost 2010). A non-invasive MR technique (Magnetic Resonance Direct Thrombus Imaging (MRDTI), without need for intravenous contrast agent, showed high sensitivity and specificity for diagnosing a first acute DVT (Fraser et al Ann Intern Med 2002). Furthermore the high signal associated with acute thrombosis was not detected 6 months after the initial acute thrombosis, making MRDTI potential relevant for distinguishing a recurrent DVT from a residual thrombosis (Westerbeek RE et al J Thromb Haemost 2008). This study evaluated the accuracy of MRDTI in patients with an acute ipsilateral recurrent DVT and patients with residual thrombosis. Patients/Methods In total 84 patients were enrolled. Of these, 42 consecutive patients had an acute ipsilateral recurrent DVT according to the current ultrasound examination standards in combination with a positive D-dimer test (≥ 500 μg/L); all patients were treated with anticoagulants. Furthermore, 42 patients were without acute signs and symptoms, however had a residual thrombosis on ultrasound examination in combination with a negative D-dimer test (< 500 μg/L). All patients received a MR examination within 48 hours of presentation. MR images were assessed in a blinded fashion by two radiologists. Sensitivity, specificity and interobserver variability were calculated. Results The images of two patients with ipsilateral recurrent DVT were not interpretable, one patient had a knee prosthesis that gave artifacts and in the other patient not the venous system of interest was imaged. The images of 40 patients with an ipsilateral recurrent DVT and of 42 patients with residual thrombosis were fully interpretable. Sensitivity was 86% (95% CI, 71 –94%) and specificity was 100% (95% CI, 89–100%) for MRDTI by the first observer; sensitivity was 88% (95% CI, 74–96%) and specificity was 100% (89–100%) by the second observer. The interobserver agreement between both observers was excellent, with a kappa statistics of 0.97 (95% CI, 0.92 – 1.0). Conclusion Our study shows reasonable sensitivity and very good specificity figures with an excellent observer agreement for imaging an ipsilateral recurrent DVT and residual thrombosis with MRDTI. The sensitivity is somewhat lower than expected; a reason could be that patients with inconclusive ultrasounds were considered as acute recurrent thrombosis by the attending physician, while in fact they had a residual thrombosis. We conclude that MRDTI has good potential in distinguishing a residual thrombosis from an acute recurrent DVT and could therefore be of high value for the diagnosis of patients with suspected acute ipsilateral recurrent DVT. This should however be further evaluated in a management outcome study in which treatment decisions are based on the results of MR. Acknowledgment This study was supported by the Netherlands Heart Foundation (grant no. 2007B146) Disclosures: No relevant conflicts of interest to declare.

scholarly journals Something old, something new…

Blood ◽  
2020 ◽  
Vol 135 (16) ◽  
pp. 1307-1308
Author(s):  
Scott M. Stevens
Keyword(s):  
Deep Vein Thrombosis ◽  
Venous Thromboembolism ◽  
Magnetic Resonance ◽  
Low Risk ◽  
Vein Thrombosis ◽  
Thrombus Imaging ◽  
Negative Study ◽  
Venous Thromboembolism Recurrence ◽  
Deep Vein

Recurrent ipsilateral deep vein thrombosis has major clinical ramifications, but is often difficult to distinguish from residual clot by ultrasound. van Dam et al demonstrated that magnetic resonance direct thrombus imaging can accurately distinguish the two, with a low risk of venous thromboembolism recurrence after a negative study.

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