Biological activity of glycine and alanine derivatives of quaternary ammonium salts (QASs) against micro‐organisms

Author(s):  
J. Rewak‐Soroczyńska ◽  
E. Paluch ◽  
A. Siebert ◽  
K. Szałkiewicz ◽  
E. Obłąk
Pathogens ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 459 ◽  
Author(s):  
Dobrawa Kwaśniewska ◽  
Ying-Lien Chen ◽  
Daria Wieczorek

Besides their positive role, microorganisms are related to a number of undesirable effects, including many diseases, biodeterioration and food spoilage, so when their presence is undesired, they must be controlled. Numerous biocides limiting the development of microorganisms have been proposed, however, in this paper the biocidal and inhibitory activity of quaternary ammonium salts (QASs) and their zwitterionic derivatives is addressed. This paper presents the current state of knowledge about the biocidal activity of QAS and their derivatives. Moreover, the known mechanisms of antimicrobial activity and the problem of emerging resistance to QAS are discussed. The latest trends in the study of surfactants and their potential use are also presented.


Author(s):  
Zahra Ould Kada ◽  
Tahar Benaissa ◽  
Nisserine Hamini-Kadar ◽  
Sofiane Daoudi

Starting from lauric acid two novel quaternary ammonium salts containing 1,3,4-Oxadiazoles nucleus derivative from N,N-Diethylaminoethyl Methacrylate (DEAEMA) and N,N-Dimethylaminoethyl Methacrylate (DMAEMA) was successfully synthesized and characterized by IR, 1H and 13C NMR, All the synthesized compounds were evaluated for their preliminary in vitro antifungal activity against three fungal strains such as Fusarium oxysporum, Fusarium commune and Fusarium rodelens. The synthesized compounds showed promising antifungal potential against the phytopathogenic test fungi.


Sign in / Sign up

Export Citation Format

Share Document