Emergence of artistic talent in progressive nonfluent aphasia: a case report

2019 ◽  
Vol 19 (6) ◽  
pp. 601-604 ◽  
Author(s):  
Akiko Hamauchi ◽  
Yosuke Hidaka ◽  
Izumi Kitamura ◽  
Yusuke Yatabe ◽  
Mamoru Hashimoto ◽  
...  
Keyword(s):  
Case Report ◽  
Nonfluent Aphasia ◽  
Progressive Nonfluent Aphasia ◽  
Artistic Talent

scholarly journals Frontotemporal dementia and neurocysticercosis: a case report

2012 ◽  
Vol 6 (1) ◽  
pp. 64-69
Author(s):  
Corina Satler ◽  
Elza Santos Maestro ◽  
Carlos Tomaz
Keyword(s):  
Case Report ◽  
Cognitive Functioning ◽  
Frontotemporal Dementia ◽  
Neuropsychiatric Symptoms ◽  
Verbal Communication ◽  
Behavioral Changes ◽  
Nonfluent Aphasia ◽  
Progressive Deterioration ◽  
History Of ◽  
Progressive Nonfluent Aphasia

ABSTRACT We report a case of a 67-year-old woman with frontotemporal dementia (FTD) and a history of neurocysticercosis. After her retirement she showed progressive behavioral changes and neuropsychiatric symptoms with relative preservation of cognitive functioning. During the next three years, the patient manifested progressive deterioration of verbal communication gradually evolving to mutism, a hallmark of cases of progressive nonfluent aphasia.

Progressive Nonfluent Aphasia With Dementia: A Case Report

1991 ◽  
Vol 4 (4) ◽  
pp. 236-240 ◽  
Author(s):  
Edward P. Feher ◽  
Rachelle S. Doody ◽  
Jean Whitehead ◽  
Francis J. Pirozzolo
Keyword(s):  
Case Report ◽  
Nonfluent Aphasia ◽  
Progressive Nonfluent Aphasia

From Progressive Nonfluent Aphasia to Corticobasal Syndrome: A Case Report of Corticobasal Degeneration

Neurocase ◽  
2006 ◽  
Vol 12 (6) ◽  
pp. 355-359 ◽  
Author(s):  
R. Sánchez-Valle ◽  
M.S. Forman ◽  
B.L. Miller ◽  
M.L. Gorno-Tempini
Keyword(s):  
Case Report ◽  
Corticobasal Degeneration ◽  
Corticobasal Syndrome ◽  
Nonfluent Aphasia ◽  
Progressive Nonfluent Aphasia

Frontotemporal Lobar Degeneration: Characterizing Semantic Binding and Abstracted Meaning Abilities

2009 ◽  
Vol 19 (4) ◽  
pp. 117-125 ◽  
Author(s):  
Raksha Anand ◽  
John Hart ◽  
Patricia S. Moore ◽  
Sandra B. Chapman
Keyword(s):  
Frontotemporal Lobar Degeneration ◽  
Assessment Tools ◽  
Progressive Decline ◽  
Cognitively Normal ◽  
Nonfluent Aphasia ◽  
Traditional Assessment ◽  
Language Measures ◽  
Semantic Object ◽  
Semantic Problem ◽  
Progressive Nonfluent Aphasia

Abstract Purpose: Frontotemporal lobar degeneration (FTLD) encompasses a group of neurodegenerative disorders characterized by gradual and progressive decline in behavior and/or language. Identifying the subtypes of FTLD can be challenging with traditional assessment tools. Growing empirical evidence suggests that language measures might be useful in differentiating FTLD subtypes. Method: In this paper, we examined the performance of five individuals with FTLD (two with frontotemporal dementia, two with semantic dementia, and one with progressive nonfluent aphasia) and 10 cognitively normal older adults on measures of semantic binding (Semantic Object Retrieval Test and semantic problem solving) and abstracted meaning (generation of interpretive statement and proverb interpretation). Results and Conclusion: A differential profile of impairment was observed in the three FTLD subtypes on these four measures. Further examination of these measures in larger groups will establish their clinical utility in differentiating the FTLD subtypes.

Autosomal Dominant Frontotemporal Lobar Degeneration in a Filipino Family with Progranulin Mutation

2021 ◽  
pp. 1-8
Author(s):  
Jacqueline Dominguez ◽  
Arlene Ng ◽  
Jeryl Yu ◽  
Anne Cristine Guevarra ◽  
Maria Luisa Daroy ◽  
...  
Keyword(s):  
Frontotemporal Lobar Degeneration ◽  
White Matter Hyperintensities ◽  
Autosomal Dominant ◽  
The Philippines ◽  
Vascular Risk ◽  
Case Presentation ◽  
Nonfluent Aphasia ◽  
Protein Tau ◽  
Review Reports ◽  
Progressive Nonfluent Aphasia

<b><i>Background:</i></b> Compared to Western populations, familial frontotemporal lobar degeneration (FTLD) is rare among Asians. Progranulin (GRN) gene mutation, which is a major cause of FTLD, is likewise rare. We present a family with FTLD from the Philippines with an autosomal dominant pattern of inheritance and GRN mutation and briefly review reports of GRN mutations in Asia. <b><i>Case Presentation:</i></b> The proband is 66 years old with progressive nonfluent aphasia (PNFA)-corticobasal syndrome . We assessed 3 generations of her pedigree and found 11 affected relatives with heterogenous phenotypes, usually behavioral variant frontotemporal dementia (FTD) and PNFA. Neuroimaging showed atrophy and hypometabolism consistent with FTD syndromes. White matter hyperintensities were seen in affected members even in the absence of vascular risk factors. A GRN mutation R110X was found in 6 members, 3 with symptoms and 3 were asymptomatic. Plasma GRN was low (&#x3c;112 ng/mL) in all mutation carriers. No mutations were found in microtubule-associated protein tau, APP, PSEN1, and PSEN2 genes, and all were APOE3. <b><i>Conclusion:</i></b> This is the first Filipino family with autosomal dominant FTD documented with GRN mutation. Identifying families and cohorts would contribute to therapeutic developments in an area with FTD-GRN.

Providing Augmentative and Alternative Communication Treatment to Persons With Progressive Nonfluent Aphasia

2010 ◽  
Vol 20 (1) ◽  
pp. 21-25 ◽  
Author(s):  
Melanie Fried-Oken ◽  
Charity Rowland ◽  
Chris Gibbons
Keyword(s):  
Augmentative And Alternative Communication ◽  
Clinical Implications ◽  
Disease Course ◽  
Alternative Communication ◽  
Future Directions ◽  
Verbal Expression ◽  
Nonfluent Aphasia ◽  
Oregon Health ◽  
And Training ◽  
Progressive Nonfluent Aphasia

Abstract Augmentative and alternative communication (AAC) intervention offers people diagnosed with progressive nonfluent aphasia (PNFA) an opportunity to continue to communicate even as verbal expression declines. To date, there are no well-controlled studies reporting the effectiveness of AAC intervention with people who present with PNFA. Further, there is a pressing need for evidence about specific AAC intervention tools, techniques, and training protocols for persons with PNFA and their communication partners. We have engaged in research studies at the Oregon Health & Science University to quantify low-tech AAC supports for people with PNFA in highly controlled, as well as naturalistic, dyadic conversations. Preliminary results suggest that AAC provides strong lexical support for people with PNFA during conversation. We predict that training participants and their partners how to use personalized, low-tech communication boards will lead to reduced conversational scaffolding by partners and prolonged effective communication as the disease course progresses. Clinical implications and future directions of our research are discussed.

scholarly journals Lexicality effects in word and nonword recall of semantic dementia and progressive nonfluent aphasia

Aphasiology ◽  
2012 ◽  
Vol 26 (3-4) ◽  
pp. 404-427 ◽  
Author(s):  
Jamie Reilly ◽  
Joshua Troche ◽  
Alison Paris ◽  
Hyejin Park ◽  
Michelene Kalinyak-Fliszar ◽  
...  
Keyword(s):  
Semantic Dementia ◽  
Nonfluent Aphasia ◽  
Progressive Nonfluent Aphasia

scholarly journals Syntactic and thematic components of sentence processing in progressive nonfluent aphasia and nonaphasic frontotemporal dementia

2007 ◽  
Vol 20 (6) ◽  
pp. 482-494 ◽  
Author(s):  
Jonathan E. Peelle ◽  
Ayanna Cooke ◽  
Peachie Moore ◽  
Luisa Vesely ◽  
Murray Grossman
Keyword(s):  
Frontotemporal Dementia ◽  
Sentence Processing ◽  
Nonfluent Aphasia ◽  
Progressive Nonfluent Aphasia
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