Differential effects of follistatin on porcine oocyte competence and cumulus cell gene expression in vitro

2017 ◽  
Vol 53 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Z Guo ◽  
MS Islam ◽  
D Liu ◽  
G Liu ◽  
L Lv ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cumulus Cell ◽  
Differential Effects ◽  
Oocyte Competence ◽  
Porcine Oocyte ◽  
Cell Gene Expression ◽  
Cell Gene

scholarly journals Human antral follicles <6 mm: a comparison between in vivo maturation and in vitro maturation in non-hCG primed cycles using cumulus cell gene expression

2012 ◽  
Vol 19 (1) ◽  
pp. 7-16 ◽  
Author(s):  
L. Guzman ◽  
T. Adriaenssens ◽  
C. Ortega-Hrepich ◽  
F. K. Albuz ◽  
I. Mateizel ◽  
...  
Keyword(s):  
Gene Expression ◽  
In Vitro Maturation ◽  
Cumulus Cell ◽  
Antral Follicles ◽  
Cell Gene Expression ◽  
Cell Gene

scholarly journals In vitro production of bovine embryos: cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence

2017 ◽  
Vol 14 (3) ◽  
pp. 482-489 ◽  
Author(s):  
G. Mazzoni ◽  
E. Razza ◽  
H. S. Pedersen ◽  
J. Secher ◽  
H. N. Kadarmideen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Bovine Embryos ◽  
In Vitro Production ◽  
Oocyte Competence ◽  
Cell Gene Expression ◽  
Vitro Production ◽  
Cell Gene

scholarly journals Oxygen-regulated gene expression in murine cumulus cells

2015 ◽  
Vol 27 (2) ◽  
pp. 407 ◽  
Author(s):  
Karen L. Kind ◽  
Kimberley K. Y. Tam ◽  
Kelly M. Banwell ◽  
Ashley D. Gauld ◽  
Darryl L. Russell ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Function ◽  
Ovarian Follicle ◽  
Cumulus Cell ◽  
Cumulus Cells ◽  
Glucose Transporter 1 ◽  
Cell Gene Expression ◽  
Regulated Gene Expression ◽  
Cell Gene

Oxygen is an important component of the environment of the cumulus–oocyte complex (COC), both in vivo within the ovarian follicle and during in vitro oocyte maturation (IVM). Cumulus cells have a key role in supporting oocyte development, and cumulus cell function and gene expression are known to be altered when the environment of the COC is perturbed. Oxygen-regulated gene expression is mediated through the actions of the transcription factors, the hypoxia-inducible factors (HIFs). In the present study, the effect of oxygen on cumulus cell gene expression was examined following in vitro maturation of the murine COC at 2%, 5% or 20% oxygen. Increased expression of HIF-responsive genes, including glucose transporter-1, lactate dehydrogenase A and BCL2/adenovirus E1B interacting protein 3, was observed in cumulus cells matured at 2% or 5%, compared with 20% oxygen. Stabilisation of HIF1α protein in cumulus cells exposed to low oxygen was confirmed by western blot and HIF-mediated transcriptional activity was demonstrated using a transgenic mouse expressing green fluorescent protein under the control of a promoter containing hypoxia response elements. These results indicate that oxygen concentration influences cumulus cell gene expression and support a role for HIF1α in mediating the cumulus cell response to varying oxygen.

Cumulus cell gene expression in luteal-phase-derived oocytes after double stimulation in one menstrual cycle

2020 ◽  
Vol 41 (3) ◽  
pp. 518-526
Author(s):  
Nona Mishieva ◽  
Bella Martazanova ◽  
Khava Bogatyreva ◽  
Anna Korolkova ◽  
Anastasia Kirillova ◽  
...  
Keyword(s):  
Gene Expression ◽  
Menstrual Cycle ◽  
Luteal Phase ◽  
Cumulus Cell ◽  
Cell Gene Expression ◽  
Cell Gene ◽  
Double Stimulation

Differential cumulus cell gene expression in young women with diminished ovarian reserve

2007 ◽  
Vol 88 ◽  
pp. S66
Author(s):  
K. Greenseid ◽  
S. Jindal ◽  
M. Nihsen ◽  
J.M. Hurwitz ◽  
N.S. Santoro ◽  
...  
Keyword(s):  
Gene Expression ◽  
Young Women ◽  
Ovarian Reserve ◽  
Cumulus Cell ◽  
Diminished Ovarian Reserve ◽  
Cell Gene Expression ◽  
Cell Gene

In Vitro TGFbeta2 Treatment Partially Rescues Cord Formation but Not Leydig Cell Gene Expression in the Betaglycan Knockout Mouse Fetal Testis.

2012 ◽  
Vol 87 (Suppl_1) ◽  
pp. 583-583
Author(s):  
Mai A. Sarraj ◽  
Ruth M. Escalona ◽  
Jock K. Findlay ◽  
Kaye L. Stenvers
Keyword(s):  
Gene Expression ◽  
Leydig Cell ◽  
Knockout Mouse ◽  
Fetal Testis ◽  
Cell Gene Expression ◽  
Cell Gene

Selective and transient in vitro effects of heat shock on alveolar type II cell gene expression

1997 ◽  
Vol 272 (1) ◽  
pp. L132-L138 ◽  
Author(s):  
H. R. Wong ◽  
M. Ryan ◽  
S. Gebb ◽  
J. R. Wispe
Keyword(s):  
Gene Expression ◽  
Heat Shock ◽  
Alveolar Type ◽  
Type Ii ◽  
Alveolar Type Ii Cell ◽  
Cell Gene Expression ◽  
Type Ii Cell ◽  
In Vitro Effects ◽  
Cell Gene

The heat shock response is a highly conserved stress response that can transiently inhibit non-heat shock protein gene expression. Although heat shock protects against acute lung injury, its effects on lung cell gene expression are not known. We studied the in vitro effects of heat shock on the expression of several genes important to alveolar type II cells. Prior induction of heat shock transiently inhibited cytokine-mediated inducible nitric oxide synthase gene expression and cytokine-mediated manganese-superoxide dismutase mRNA expression in murine lung epithelium. In contrast, heat shock had no effect on expression of surfactant protein (SP) A or B mRNA, or SP-B peptide synthesis. Cell survival studies indicated that the inhibitory effects were not secondary to cytotoxicity. Previous heat shock also modestly enhanced the ability of cells to withstand oxidant stress. We conclude that in vitro heat shock has selective and transient inhibitory effects on alveolar type II cell gene expression. Transient inhibition of cytokine-inducible genes, with concomitant conservation of genes required for normal respiratory function (SP) may explain, in part, the mechanism by which heat shock protects during acute lung injury.

Association of cumulus cell gene expression with embryological indicators in assisted reproductive technology programs

2016 ◽  
Vol 7_2016 ◽  
pp. 60-66
Author(s):  
Safronova N.A. Safronova ◽  
Kalinina E.A. Kalinina ◽  
Donnikov A.E. Donnikov ◽  
Burmenskaya O.V. Burmenskaya ◽  
Makarova N.P. Makarova ◽  
...  
Keyword(s):  
Gene Expression ◽  
Assisted Reproductive Technology ◽  
Cumulus Cell ◽  
Reproductive Technology ◽  
Cell Gene Expression ◽  
Technology Programs ◽  
Cell Gene

In vitro antioxidant and antigenotoxic potentials of 3,5-O-di-galloylquinic acid extracted from Myrtus communis leaves and modulation of cell gene expression by H2O2

2011 ◽  
Vol 32 (5) ◽  
pp. 333-341 ◽  
Author(s):  
Skandrani Ines ◽  
Bouhlel Ines ◽  
Bhouri Wissem ◽  
Ben Sghaier Mohamed ◽  
Hayder Nawel ◽  
...  
Keyword(s):  
Gene Expression ◽  
Myrtus Communis ◽  
Cell Gene Expression ◽  
Cell Gene

Association between early embryo morphokinetics plus cumulus cell gene expression and assisted reproduction outcomes in polycystic ovary syndrome women

2019 ◽  
Vol 38 (2) ◽  
pp. 139-151 ◽  
Author(s):  
Nasim Tabibnejad ◽  
Mohammad Hasan Sheikhha ◽  
Nasrin Ghasemi ◽  
Farzaneh Fesahat ◽  
Mehrdad Soleimani ◽  
...  
Keyword(s):  
Gene Expression ◽  
Polycystic Ovary Syndrome ◽  
Assisted Reproduction ◽  
Polycystic Ovary ◽  
Cumulus Cell ◽  
Early Embryo ◽  
Ovary Syndrome ◽  
Cell Gene Expression ◽  
Cell Gene
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