Invasive procedures in the oral cavity of individuals with Bernard–Soulier syndrome: An integrative review

2021 ◽  
Author(s):  
Victor Tieghi Neto ◽  
Vivian Palata Viola ◽  
Luiz Alberto Valente Soares Júnior ◽  
Paulo Sergio da Silva Santos
Keyword(s):  
Oral Cavity ◽  
Integrative Review ◽  
Invasive Procedures ◽  
Bernard Soulier Syndrome

scholarly journals Nursing Care with the Skin of Hospitalized Newborns: Integrative Review

10.3823/2459 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Ana Dulce Amorim Santos Soares ◽  
Silvana Santiago da Rocha ◽  
Augusto Cezar Antunes de Araujo Filho ◽  
Rosana Dos Santos Costa ◽  
Márcia Teles de Oliveira Gouveia ◽  
...  
Keyword(s):  
Risk Factors ◽  
Key Words ◽  
Nursing Care ◽  
Skin Lesions ◽  
Integrative Review ◽  
Transparent Film ◽  
Invasive Procedures ◽  
Skin Injuries ◽  
Prevention And Treatment

The objective was to analyze the scientific collection on nursing care with the skin of hospitalized newborns. In order to reach the objective, an integrative review was conducted. The search for primary studies was performed in the databases LILACS, MEDLINE, BDENF and PUBMED. The included studies (n=10) were grouped into thematic categories: risk factors for skin lesions in hospitalized newborns and their consequences; and nursing care to promote the integrity of the skin of hospitalized newborns. The main care identified were lubrication with emollient agents, use of hydrocolloids and transparent film, changes in decubitus, hygiene techniques, phototherapy and invasive procedures. The results of the review offer guidance for the conduction of researches that investigate interventions that are more effective in the prevention and treatment of skin injuries and their consequences. Key words: Nursing Care, Newborn, Skin.

scholarly journals Action Of Propolis On Microorganisms Of The Oral Cavity: An Integrative Review

10.3823/1717 ◽  
2015 ◽  
Author(s):  
Anne Milane Formiga Bezerra ◽  
Maria do Carmo Andrade Duarte de Farias ◽  
Kévia Katiúcia Santos Bezerra ◽  
Antônio Fernandes Filho ◽  
Geofabio Sucupira Casimiro ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Integrative Review

Bernard-Soulier in Iceland. Bleeding Symptoms and Platelet Parameters in Patients, Carriers and Controls.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 1095-1095
Author(s):  
Pall Torfi Onundarson ◽  
Elisabet R. Birgisdottir ◽  
Gudrun Bragadottir ◽  
Bylgja Hilmarsdottir ◽  
Brynja Gudmundsdottir ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Platelet Aggregation ◽  
Oral Cavity ◽  
Carrier Status ◽  
Swedish Mutation ◽  
Platelet Disorder ◽  
Hematological Abnormalities ◽  
Mucosal Bleeding ◽  
Normal Controls ◽  
Bernard Soulier Syndrome

Abstract Bernard Soulier syndrome is a rare platelet disorder characterized by macrothrombocytopenia and absence of platelet aggregation in response to ristocetin due to inherited structural abnormalities in the glycoptein 1B complex. Due to the rarity of this disorder no systematic controlled evaluation has been reported to define the hematological abnormalities and clinical symptoms of these patients. In order to evaluate these findings associated with both Bernard Soulier syndrome and carrier status of glycoprotein 1B-alpha (GP1Bα) mutations we have conducted a nation-wide study in Iceland. All patients with Bernard Soulier syndrome diagnosed in Iceland are referred to the Landspitali University Hospital hemostasis center, a total of twelve patients. Of these, ten were available for the study along with 21 heterozygote carriers (first or second degree relatives) and 25 normal controls. All participating subjects answered a detailed questionnaire on bleeding history and had blood tests, including a complete blood count, coagulation tests, platelet aggregation, PFA-100 closure times, platelet flow cytometry, and DNA analysis to define the underlying GP1Bα mutational status. A diagnosis of Bernard Soulier syndrome was confirmed by platelet ristocetin aggregation and flow cytometry in all patients. Of these ten patients, seven were homozygous for a specific Icelandic mutation, T283 to C (Cys65 to Arg) in the conserved leucine-rich repeats within the ligand-binding region of platelet GP1Bα. Two patients had compound heterozygosity, Cys65 to Arg and a previously described Swedish mutation (Karlstad mutation), G1584 to A (Trp 498 to Stop) with both mutations in GP1Bα. One patient was compound heterozygous for the Karlstad mutation as well as an uncharacterized mutation. Of the 21 carriers, 14 had the Icelandic mutation and 6 had the Karlstad mutation and one had the uncharacterized mutation. As expected all patients had very significant macrothrombocytopenia with no expression of the GP1B complex on flow cytometry and absolute absence of ristocetin aggretion response. Compared to normal controls, the BS patients reported excessive bleeding manifested by markedly increased bruisability, prolonged small cut bleeding and increased mucosal bleeding (epistaxis, oral cavity, menstruation). Heterozygote carriers also reported moderately increased bruisability compared to normal controls, longer bleeding from small cuts and increased mucosal bleeding (epistaxis, oral cavity). On blood analysis the carriers had significantly lower platelets counts (189 vs. 266 × 109/L, p<0.0001 ) and larger platelets (9.6 fl vs. 7.8 fl, p<0.0001 ) than controls. The PFA-100 closure times (both CT c/epi and CT c/ADP) were markedly prolonged in all patients while carriers and controls had similar normal values. In this nation-wide study of Bernard Soulier syndrome we have characterized the clinical and hematological symptoms of patients and carriers. As expected the patients have significant clinical mucosal bleeding symptoms and hematological abnormalities. Interestingly we find evidence of mild platelet dysfunction in heterozygote carriers marked by symptoms of increased mucosal bleeding and lower platelet counts as well as larger platelets than controls.

scholarly journals Streptococcus gordonii: A Rare Cause of Infective Endocarditis

2019 ◽  
Vol 2019 ◽  
pp. 1-2 ◽  
Author(s):  
Natalia Mosailova ◽  
Justina Truong ◽  
Tyson Dietrich ◽  
John Ashurst
Keyword(s):  
Infective Endocarditis ◽  
Oral Cavity ◽  
Antibiotic Prophylaxis ◽  
Streptococcus Gordonii ◽  
Invasive Procedures ◽  
Dental Abscess ◽  
Dental Procedures ◽  
Life Threatening

Infective endocarditis is a rare but life-threatening disease seen across the globe. Organisms from the oral cavity still represent a large proportion of pathogens seen in endocarditis and can be from either daily dental routines or invasive procedures. With the recent changes to antibiotic prophylaxis for infective endocarditis prior to dental procedures, the physician must have a heightened degree of suspicion when presented with a patient with undifferenced sepsis following dental procedures. The authors present a case of infective endocarditis caused by Streptococcus gordonii after the drainage of a dental abscess.

Patient psychologic preparation for invasive procedures: An integrative review

2000 ◽  
Vol 18 (4) ◽  
pp. 117-122 ◽  
Author(s):  
Lisa R. Moline
Keyword(s):  
Integrative Review ◽  
Invasive Procedures

Oral and Oropharyngeal Sensory Function in Adults With Chronic Obstructive Pulmonary Disease

2020 ◽  
Vol 29 (2) ◽  
pp. 864-872
Author(s):  
Fernanda Borowsky da Rosa ◽  
Adriane Schmidt Pasqualoto ◽  
Catriona M. Steele ◽  
Renata Mancopes
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Oral Cavity ◽  
Pulmonary Disease ◽  
Thermal Sensation ◽  
Sensory Function ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Age Related ◽  
Copd Patients

Introduction The oral cavity and pharynx have a rich sensory system composed of specialized receptors. The integrity of oropharyngeal sensation is thought to be fundamental for safe and efficient swallowing. Chronic obstructive pulmonary disease (COPD) patients are at risk for oropharyngeal sensory impairment due to frequent use of inhaled medications and comorbidities including gastroesophageal reflux disease. Objective This study aimed to describe and compare oral and oropharyngeal sensory function measured using noninstrumental clinical methods in adults with COPD and healthy controls. Method Participants included 27 adults (18 men, nine women) with a diagnosis of COPD and a mean age of 66.56 years ( SD = 8.68). The control group comprised 11 healthy adults (five men, six women) with a mean age of 60.09 years ( SD = 11.57). Spirometry measures confirmed reduced functional expiratory volumes (% predicted) in the COPD patients compared to the control participants. All participants completed a case history interview and underwent clinical evaluation of oral and oropharyngeal sensation by a speech-language pathologist. The sensory evaluation explored the detection of tactile and temperature stimuli delivered by cotton swab to six locations in the oral cavity and two in the oropharynx as well as identification of the taste of stimuli administered in 5-ml boluses to the mouth. Analyses explored the frequencies of accurate responses regarding stimulus location, temperature and taste between groups, and between age groups (“≤ 65 years” and “> 65 years”) within the COPD cohort. Results We found significantly higher frequencies of reported use of inhaled medications ( p < .001) and xerostomia ( p = .003) in the COPD cohort. Oral cavity thermal sensation ( p = .009) was reduced in the COPD participants, and a significant age-related decline in gustatory sensation was found in the COPD group ( p = .018). Conclusion This study found that most of the measures of oral and oropharyngeal sensation remained intact in the COPD group. Oral thermal sensation was impaired in individuals with COPD, and reduced gustatory sensation was observed in the older COPD participants. Possible links between these results and the use of inhaled medication by individuals with COPD are discussed.

Transoral Resection for Cancer of the Oral Cavity

1972 ◽  
Vol 5 (2) ◽  
pp. 321-325 ◽  
Author(s):  
G. David King
Keyword(s):  
Oral Cavity ◽  
Transoral Resection

The Jejunal Free Flap In Oral Cavity And Pharyngeal Reconstruction

1994 ◽  
Vol 27 (6) ◽  
pp. 1159-1170 ◽  
Author(s):  
Bruce H. Haughey, MBChB, MS
Keyword(s):  
Oral Cavity ◽  
Free Flap ◽  
Pharyngeal Reconstruction
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