DNA Detection RevealsMycobacterium tuberculosisComplex Shedding Routes in Its Wildlife Reservoir the Eurasian Wild Boar

2015 ◽  
Vol 64 (3) ◽  
pp. 906-915 ◽  
Author(s):  
J. A. Barasona ◽  
M. J. Torres ◽  
J. Aznar ◽  
C. Gortázar ◽  
J. Vicente
2010 ◽  
Vol 37 (11) ◽  
pp. 725-736 ◽  
Author(s):  
Ruth C. Galindo ◽  
Pilar M. Muñoz ◽  
María J. de Miguel ◽  
Clara M. Marin ◽  
Javier Labairu ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Beatriz Beltrán-Beck ◽  
Cristina Ballesteros ◽  
Joaquín Vicente ◽  
José de la Fuente ◽  
Christian Gortázar

Eurasian wild boar (Sus scrofa) is the main wildlife reservoir for tuberculosis (TB) in Iberia. This review summarizes the current knowledge on wild boar vaccination including aspects of bait design, delivery and field deployment success; wild boar response to vaccination with Bacillus Calmette-Guérin (BCG) and inactivated Mycobacterium bovis; and wild boar vaccination biosafety issues as well as prospects on future research. Oral vaccination with BCG in captive wild boar has shown to be safe with significant levels of protection against challenge with virulentM. bovis. An oral vaccination with a new heat-killedM. bovisvaccine conferred a protection similar to BCG. The study of host-pathogen interactions identified biomarkers of resistance/susceptibility to tuberculosis in wild boar such as complement component 3 (C3) and methylmalonyl coenzyme A mutase (MUT) that were used for vaccine development. Finally, specific delivery systems were developed for bait-containing vaccines to target different age groups. Ongoing research includes laboratory experiments combining live and heat-killed vaccines and the first field trial for TB control in wild boar.


2020 ◽  
Vol 23 (11) ◽  
pp. 28-33
Author(s):  
S.P. Yatsentyuk ◽  
◽  
D.A. Rudnyayev ◽  
Yu.I. Pobolelova ◽  
M.S. Krasnikova ◽  
...  

2011 ◽  
Vol 1 (4) ◽  
pp. 325-333
Author(s):  
Filiz Kuralay ◽  
Hakan Karadeniz ◽  
Mihrican Muti ◽  
Arzum Erdem

2020 ◽  
Vol 47 (5) ◽  
pp. 314-320 ◽  
Author(s):  
D. Allen Roberts ◽  
Stephen E. Hawes ◽  
Mame D. Bousso Bao ◽  
Anna Julienne Ndiaye ◽  
Daouda Gueye ◽  
...  

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