Marek's disease viruses circulating in commercial poultry in Italy in the years 2015–2018 are closely related by their meq gene phylogeny

2019 ◽  
Vol 67 (1) ◽  
pp. 98-107 ◽  
Author(s):  
Giulia Mescolini ◽  
Caterina Lupini ◽  
Irit Davidson ◽  
Paola Massi ◽  
Giovanni Tosi ◽  
...  
Keyword(s):  
Marek's Disease ◽  
Marek’S Disease ◽  
Gene Phylogeny ◽  
Commercial Poultry ◽  
Meq Gene

Report of a new meq gene size: The first study on genetic characterisation of Marek’s disease viruses circulating in Iranian commercial layer and backyard chicken

2021 ◽  
pp. 1-8
Author(s):  
A. Molouki ◽  
A. Ghalyanchilangeroudi ◽  
M. Abdoshah ◽  
A. Shoushtari ◽  
A. Abtin ◽  
...  
Keyword(s):  
Marek's Disease ◽  
Marek’S Disease ◽  
Gene Size ◽  
Genetic Characterisation ◽  
Backyard Chicken ◽  
Meq Gene

scholarly journals Characterization of Marek’s disease virus and phylogenetic analyses of meq gene from an outbreak in poultry in Meghalaya of Northeast India

VirusDisease ◽  
2018 ◽  
Vol 29 (2) ◽  
pp. 167-172 ◽  
Author(s):  
Kekungu-u Puro ◽  
Uttaran Bhattacharjee ◽  
Samprity Baruah ◽  
Arnab Sen ◽  
Samir Das ◽  
...  
Keyword(s):  
Disease Virus ◽  
Phylogenetic Analyses ◽  
Northeast India ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Meq Gene

scholarly journals Molecular characterization of the meq gene of Marek's disease viruses detected in unvaccinated backyard chickens reveals the circulation of low- and high-virulence strains

2019 ◽  
Vol 98 (8) ◽  
pp. 3130-3137 ◽  
Author(s):  
Giulia Mescolini ◽  
Caterina Lupini ◽  
Viviana Felice ◽  
Alessandro Guerrini ◽  
Flavio Silveira ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
High Virulence ◽  
Backyard Chickens ◽  
Meq Gene

scholarly journals Industry-Wide Surveillance of Marek's Disease Virus on Commercial Poultry Farms

2017 ◽  
Vol 61 (2) ◽  
pp. 153 ◽  
Author(s):  
David A. Kennedy ◽  
Christopher Cairns ◽  
Matthew J. Jones ◽  
Andrew S. Bell, ◽  
Rahel M. Salathé ◽  
...  
Keyword(s):  
Disease Virus ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Poultry Farms ◽  
Commercial Poultry

Isolation of a Field Marek’s Disease Virus with Acute Oncogenicity from Tibetan Chickens in China and Sequence Analysis of Oncogenic Genes

2011 ◽  
Vol 343-344 ◽  
pp. 538-544
Author(s):  
Ming Xing Tian ◽  
Rui Deng ◽  
Yang Zhao ◽  
Min Li ◽  
San Jie Cao ◽  
...  
Keyword(s):  
Disease Virus ◽  
Challenge Test ◽  
Point Mutations ◽  
Repeated Sequence ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Specific Pathogen ◽  
Meq Gene

A field Marek’s disease virus (MDV), named as BY strain, was firstly isolated from Tibetan chickens in Sichuan province, China, by method of co-cultivation of the lymphocytes with duck embryo fibroblasts (DEF). Analysis of the oncogenic genes showed that there were 2 copies of 132-bp repeated sequence in long terminal repeat of the BY strain, The nucleotide and amino acid sequence identities of Meq gene of BY strain with other prevalent MDV strains in China were 97.6-100.0% and 98.8-100.0%, respectively, and some point mutations assumed to be relevant to the oncogenecity of MDV also existed in the Meq gene of BY strain. The result of animal challenge test on specific-pathogen-free (SPF) chickens showed lymphomas may occur in a variety of organs as early as 18 days post challenge, and the rate of tumor occurrences and mortalities reached to 73.33% and 66.67% in HVT immunized chickens, respectively. In conclusion, an MDV strain charac-terized of acute oncogenicity was isolated from Tibetan chickens in China, though there were no obvious difference between the oncogenic genes of this strain and other virulent MDV strains isolated in China in recent years.

scholarly journals Industry-wide surveillance of Marek’s disease virus on commercial poultry farms

2016 ◽  
Author(s):  
David A. Kennedy ◽  
Christopher Cairns ◽  
Matthew J. Jones ◽  
Andrew S. Bell ◽  
Rahel M. Salathé ◽  
...  
Keyword(s):  
Disease Virus ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Wild Type Virus ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Wild Type ◽  
Virus Prevalence ◽  
Poultry Farms ◽  
Commercial Poultry

AbstractMarek’s disease virus is a herpesvirus of chickens that costs the worldwide poultry industry over 1 billion USD annually. Two generations of Marek’s disease vaccines have shown reduced efficacy over the last half century due to evolution of the virus. Understanding where the virus is present may give insight into whether continued reductions in efficacy are likely. We conducted a three-year surveillance study to assess the prevalence of Marek’s disease virus on commercial poultry farms, determine the effect of various factors on virus prevalence, and document virus dynamics in broiler chicken houses over short (weeks) and long (years) timescales. We extracted DNA from dust samples collected from commercial chicken and egg production facilities in Pennsylvania, USA. Quantitative polymerase chain reaction (qPCR) was used to assess wild-type virus detectability and concentration. Using data from 1018 dust samples with Bayesian generalized linear mixed effects models, we determined the factors that correlated with virus prevalence across farms. Maximum likelihood and autocorrelation function estimation on 3727 additional dust samples were used to document and characterize virus concentrations within houses over time. Overall, wild-type virus was detectable at least once on 36 of 104 farms at rates that varied substantially between farms. Virus was detected in 1 of 3 broiler-breeder operations (companies), 4 of 5 broiler operations, and 3 of 5 egg layer operations. Marek’s disease virus detectability differed by production type, bird age, day of the year, operation (company), farm, house, flock, and sample. Operation (company) was the most important factor, accounting for between 12% and 63.4% of the variation in virus detectability. Within individual houses, virus concentration often dropped below detectable levels and reemerged later. These data characterize Marek’s disease virus dynamics, which are potentially important to the evolution of the virus.

scholarly journals Diversity of Meq gene from clinical Marek’s disease virus infection in Saudi Arabia

2016 ◽  
Vol 9 (6) ◽  
pp. 572-578 ◽  
Author(s):  
Mahmoud H. A. Mohamed ◽  
Ibrahim M. El-Sabagh ◽  
Malik A. Al-Habeeb ◽  
Yousef M. Al-Hammady
Keyword(s):  
Saudi Arabia ◽  
Virus Infection ◽  
Disease Virus ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Meq Gene
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