scholarly journals Detection of African swine fever virus genotype XV in a sylvatic cycle in Saadani National Park, Tanzania

Author(s):  
Emma Peter ◽  
Eunice Machuka ◽  
Dedan Githae ◽  
Edward Okoth ◽  
Sarah Cleaveland ◽  
...  
2001 ◽  
Vol 2 (2) ◽  
pp. 121-128 ◽  
Author(s):  
Steven B. Kleiboeker ◽  
Glen A. Scoles

AbstractAfrican swine fever virus (ASFV) is the only known DNA arbovirus and the sole member of the family Asfarviridae. It causes a lethal, hemorrhagic disease in domestic pigs. ASFV is enzootic in sub-Saharan Africa and is maintained in a sylvatic cycle by infecting both wild members of the Suidae (e.g. warthogs) and the argasid tickOrnithodoros porcinus porcinus. The pathogenesis of ASFV inO. porcinus porcinusticks is characterized by a low infectious dose, lifelong infection, efficient transmission to both pigs and ticks, and low mortality until after the first oviposition. ASFV pathogenesis in warthogs is characterized by an inapparent infection with transient, low viremic titers. ThusO. porcinus porcinusticks probably constitute the most important natural vector of ASFV, although both the mammalian and tick hosts are probably required for the maintenance of ASFV in the sylvatic cycle. The mechanism of ASFV transmission from the sylvatic cycle to domestic pigs is probably through infected ticks feeding on pigs. In addition toO. porcinus porcinus, a number of North American, Central American and Caribbean species ofOrnithodoroshave been shown to be potential vectors of ASFV.


Author(s):  
Jose A. Barasona ◽  
Carmina Gallardo ◽  
Estefanía Cadenas-Fernández ◽  
Cristina Jurado ◽  
Belén Rivera ◽  
...  

2008 ◽  
Vol 89 (2) ◽  
pp. 397-408 ◽  
Author(s):  
David A. G. Chapman ◽  
Vasily Tcherepanov ◽  
Chris Upton ◽  
Linda K. Dixon

The genomic coding sequences, apart from the inverted terminal repeats and cross-links, have been determined for two African swine fever virus (ASFV) isolates from the same virus genotype, a non-pathogenic isolate from Portugal, OURT88/3, and a highly pathogenic isolate from West Africa, Benin 97/1. These genome sequences were annotated and compared with that of a tissue culture-adapted isolate, BA71V. The genomes range in length between 170 and 182 kbp and encode between 151 and 157 open reading frames (ORFs). Compared to the Benin 97/1 isolate, the OURT88/3 and BA71V isolates have deletions of 8–10 kbp that encode six copies of the multigene family (MGF) 360 and either one MGF 505/530 copy in the BA71V or two copies in the OURT88/3 isolate. The BA71V isolate has a deletion, close to the right end of the genome, of 3 kbp compared with the other isolates. The five ORFs in this region include an additional copy of an ORF similar to that encoding the p22 virus structural protein. The OURT88/3 isolate has interruptions in ORFs that encode a CD2-like and a C-type lectin protein. Variation between the genomes is observed in the number of copies of five different MGFs. The 109 non-duplicated ORFs conserved in the three genomes encode proteins involved in virus replication, virus assembly and modulation of the host's defences. These results provide information concerning the genetic variability of African swine fever virus isolates that differ in pathogenicity.


2021 ◽  
Vol 10 (26) ◽  
Author(s):  
Adeyinka J. Adedeji ◽  
Pam D. Luka ◽  
Rebecca B. Atai ◽  
Toyin A. Olubade ◽  
Dupe A. Hambolu ◽  
...  

A confirmed African swine fever (ASF) outbreak in Nigeria was further investigated by partial sequencing of B464L and E183L genes of the ASF virus (ASFV). Results revealed the first-time presence of ASFV genotype II in Nigeria and West Africa. This finding has serious implications for control measures and food security.


2015 ◽  
Vol 160 (6) ◽  
pp. 1407-1414 ◽  
Author(s):  
Hovakim Zakaryan ◽  
Victorya Cholakyans ◽  
Lusine Simonyan ◽  
Alla Misakyan ◽  
Elena Karalova ◽  
...  

2018 ◽  
Vol 7 (13) ◽  
Author(s):  
Charles Masembe ◽  
Vattipally B. Sreenu ◽  
Ana Da Silva Filipe ◽  
Gavin S. Wilkie ◽  
Peter Ogweng ◽  
...  

Complete genome sequences of five African swine fever virus isolates were determined directly from clinical material obtained from domestic pigs in Uganda. Four sequences were essentially identical to each other, and all were closely related to the only known genome sequence of p72 genotype IX.


Author(s):  
Ulaankhuu Ankhanbaatar ◽  
Tserenchimed Sainnokhoi ◽  
Buyantogtokh Khanui ◽  
Gerelmaa Ulziibat ◽  
Tserenjav Jargalsaikhan ◽  
...  

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