Incidence, Risk Factors, and Obstetrical Outcomes of Women with Breast Cancer in Pregnancy

2012 ◽  
Vol 18 (6) ◽  
pp. 564-568 ◽  
Author(s):  
Haim Arie Abenhaim ◽  
Laurent Azoulay ◽  
Christina A. Holcroft ◽  
Lionel A. Bure ◽  
Jonathan Assayag ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Obstetrical Outcomes ◽  
Cancer In Pregnancy ◽  
Incidence Risk ◽  
In Pregnancy

Breast Cancer in Pregnancy

2010 ◽  
Vol 16 ◽  
pp. S22-S25 ◽  
Author(s):  
Francesca Rovera ◽  
Francesco Frattini ◽  
Alessandra Coglitore ◽  
Marina Marelli ◽  
Stefano Rausei ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer In Pregnancy ◽  
In Pregnancy

Preeclampsia Problem-Based Learning Discussion

2018 ◽  
pp. 249-254
Author(s):  
Shamantha Reddy ◽  
Yelena Spitzer
Keyword(s):  
Risk Factors ◽  
Anesthetic Management ◽  
Problem Based Learning ◽  
Preeclamptic Patient ◽  
Prevention And Treatment ◽  
Incidence Risk ◽  
Blurry Vision ◽  
Hypertensive Diseases ◽  
In Pregnancy

This chapter is a problem based learning discussion about the hypertensive diseases in pregnancy and describes incidence, risk factors, etiology, prevention and treatment of the disease. The chapter discusses risk factors for preeclampsia, the etiology and pathogenesis of preeclampsia; prevention of preeclampsia; management of preeclamptic patients; treatment of hypertension in pregnancy; eclampsia prevention and treatment; anesthetic management, including general anesthesia, of the preeclamptic patient; invasive monitoring in the preeclamptic patient; and management of HELLP syndrome. The chapter uses the case study of a 32-year-old woman at 39 weeks gestation who presents to the labor floor with headache, blurry vision, and abdominal pain for 1 day.

scholarly journals Breast cancer in pregnancy: case report

2010 ◽  
Vol 5 (1) ◽  
Author(s):  
M Tobe ◽  
C Stephen ◽  
K Vasantha ◽  
A Shirley ◽  
R Bernard ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Cancer In Pregnancy ◽  
In Pregnancy

scholarly journals Acute Coronary Syndrome in Pregnancy

2009 ◽  
Vol 3 ◽  
pp. CMC.S3284 ◽  
Author(s):  
Douglas Wright ◽  
Claire Kenny-Scherber ◽  
Alison Montgomery ◽  
Omid Salehian
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Present Report ◽  
Rare Event ◽  
Physiological Changes ◽  
Coronary Syndrome ◽  
Incidence Risk ◽  
St Elevation ◽  
In Pregnancy

Acute coronary syndrome (ACS) in pregnancy has traditionally been considered to be a rare event, but the combination of normal physiological changes of pregnancy and more prevalent cardiovascular risk factors are increasing its incidence in this population. The present report describes a 39 year-old woman that is seven weeks pregnant presenting with a non ST elevation myocardial infarction. The incidence, risk factors, pathophysiology and management of ACS in pregnancy are discussed.

Birthweight and Chemotherapy Exposure in Women Diagnosed with Breast Cancer during Pregnancy

2020 ◽  
Author(s):  
Taylor S. Freret ◽  
Pedro Exman ◽  
Erica L. Mayer ◽  
Sarah E. Little ◽  
Katherine E. Economy
Keyword(s):  
Breast Cancer ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Chemotherapy Regimen ◽  
Small Sample ◽  
Maternal Outcomes ◽  
Z Score ◽  
Cancer In Pregnancy ◽  
Lower Birthweight ◽  
In Pregnancy

Objective Breast cancer is one of the most frequently diagnosed cancers in pregnancy and is commonly treated with chemotherapy. To date, studies examining effects of chemotherapy during pregnancy on fetal growth have yielded conflicting results, and most are limited by small sample sizes or are nonspecific with respect to cytotoxic regimen or type of cancer treated. We sought to evaluate the effect of chemotherapy for breast cancer in pregnancy on birthweight and small for gestational age infants. Study Design This is a retrospective cohort study of 74 women diagnosed with pathologically confirmed breast cancer during pregnancy between 1997 and 2018 at one of three academic medical centers, who had a singleton birth with known birthweight. Forty-nine received chemotherapy and 25 did not receive chemotherapy. Linear regression modeling was used to compare birthweight (by gestational age and sex-specific z-score) by chemotherapy exposure. Subanalyses of specific chemotherapy regimen and duration of chemotherapy exposure were also performed. Placental, neonatal, and maternal outcomes were also analyzed by chemotherapy exposure. Results In the adjusted model, chemotherapy exposure was associated with lower birthweight (∆ z-score =  − 0.49, p = 0.03), but similar rates of small for gestational age (defined as birthweight <10th percentile for gestational age) infants (8.2 vs. 8.0%, p = 1.0; Fisher’s exact test). Each additional week of chemotherapy (∆ z-score =  − 0.05, p = 0.03) was associated with decreased birthweight, although no association was found with specific chemotherapy regimen. Chemotherapy exposure was associated with lower median placental weight percentile by gestational age (9th vs. 75th, p < 0.05). Secondary maternal outcomes were similar between the group that did and did not receive chemotherapy. Conclusion Chemotherapy for breast cancer in pregnancy in this cohort is associated with lower birthweight but no difference in the rate of small for gestational age infants. Key Points

scholarly journals Identification and Management of Lymphedema in Patients With Breast Cancer

2019 ◽  
Vol 15 (5) ◽  
pp. 255-262 ◽  
Author(s):  
Pavankumar Tandra ◽  
Avyakta Kallam ◽  
Jairam Krishnamurthy
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Treatment ◽  
Early Stage ◽  
Financial Burden ◽  
Breast Cancer Treatment ◽  
Initial Diagnosis ◽  
Axillary Surgery ◽  
Incidence Risk ◽  
End Stage

Breast cancer–related lymphedema (BCRL) is a potentially debilitating and often irreversible complication of breast cancer treatment. Risk of BCRL is proportional to the extent of axillary surgery and radiation. Other risk factors include obesity and infections. Given the 5-year survival rate of 90% and its potential impact on the quality of life of survivors of breast cancer, BCRL has become a significant financial burden on the health care system. Minimizing axillary surgery and radiation has been proven to reduce the risk of BCRL. Comprehensive multidisciplinary assessment at the time of initial diagnosis; early referral to physical therapy after surgery; and patient education regarding weight loss, skin, and nail care are cornerstones of the management of early-stage lymphedema. End-stage lymphedema may benefit from referral to a plastic surgeon specializing in lymphedema surgery. In this review, we attempt to review the incidence, risk factors, staging, prevention, and management of this complication of breast cancer treatment. We also describe our multidisciplinary approach for the prevention of this complication at the time of initial diagnosis.

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