scholarly journals AtC3H14, a plant-specific tandem CCCH zinc-finger protein, binds to its target mRNAs in a sequence-specific manner and affects cell elongation inArabidopsis thaliana

2014 ◽  
Vol 80 (5) ◽  
pp. 772-784 ◽  
Author(s):  
Won-Chan Kim ◽  
Joo-Yeol Kim ◽  
Jae-Heung Ko ◽  
Hunseung Kang ◽  
Jungmook Kim ◽  
...  
Keyword(s):  
Zinc Finger ◽  
Cell Elongation ◽  
Zinc Finger Protein ◽  
Target Mrnas ◽  
Ccch Zinc Finger ◽  
Finger Protein ◽  
Specific Manner ◽  
Tandem Ccch Zinc Finger

The CCCH zinc finger protein gene AtZFP1 improves salt resistance in Arabidopsis thaliana

2014 ◽  
Vol 86 (3) ◽  
pp. 237-253 ◽  
Author(s):  
Guoliang Han ◽  
Mingjie Wang ◽  
Fang Yuan ◽  
Na Sui ◽  
Jie Song ◽  
...  
Keyword(s):  
Arabidopsis Thaliana ◽  
Zinc Finger ◽  
Protein Gene ◽  
Zinc Finger Protein ◽  
Salt Resistance ◽  
Zinc Finger Protein Gene ◽  
Ccch Zinc Finger ◽  
Finger Protein

Knockout of the CCCH zinc finger protein TcZC3H31 blocks Trypanosoma cruzi differentiation into the infective metacyclic form

2018 ◽  
Vol 221 ◽  
pp. 1-9 ◽  
Author(s):  
Monica Visnieski Alcantara ◽  
Rafael Luis Kessler ◽  
Rosana Elisa Gonçalves Gonçalves ◽  
Newmar Pinto Marliére ◽  
Alessandra Aparecida Guarneri ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Ccch Zinc Finger ◽  
Finger Protein

scholarly journals Stimulation of Polo-Like Kinase 3 mRNA Decay by Tristetraprolin

2009 ◽  
Vol 29 (8) ◽  
pp. 1999-2010 ◽  
Author(s):  
Thierry J. Horner ◽  
Wi S. Lai ◽  
Deborah J. Stumpo ◽  
Perry J. Blackshear
Keyword(s):  
Protein Kinase ◽  
Cell Lines ◽  
Zinc Finger Protein ◽  
Fibroblast Cell ◽  
Mouse Fibroblast ◽  
Serum Stimulation ◽  
Ccch Zinc Finger ◽  
Finger Protein ◽  
Tandem Ccch Zinc Finger ◽  
Fibroblast Cell Lines

ABSTRACT Polo-like protein kinase 3 (Plk3) has been proposed to regulate entry into S phase and promote apoptosis in response to oxidative stress. Its mRNA contains three AU-rich elements (AREs) in its 3′ untranslated region (3′-UTR) that can contribute to the rapid degradation of labile transcripts. We investigated the possibility that tristetraprolin (TTP), a tandem CCCH zinc finger protein, could promote the decay of Plk3 transcripts. TTP is known to stimulate the deadenylation and decay of mRNAs possessing one or more copies of the consensus nonamer motif UUAUUUAUU. In stable mouse fibroblast cell lines derived from wild-type and TTP knockout littermates, the decay of Plk3 transcripts after serum stimulation was slowed in the absence of TTP. The specificity of TTP for promoting the degradation of Plk3 was demonstrated by the unaltered decay of Plk3 mRNA in cell lines deficient in the TTP family members ZFP36L1 and ZFP36L2. We also found that the AREs present in the Plk3 transcript were essential for both the binding of TTP to the 3′-UTR and promoting the destruction of target transcripts in cotransfection experiments. The regulation of Plk3 mRNA stability by TTP may influence the control of the cell cycle by this protein kinase.

TcZFP1: a CCCH zinc finger protein of Trypanosoma cruzi that binds poly-C oligoribonucleotides in vitro

2004 ◽  
Vol 319 (1) ◽  
pp. 169-177 ◽  
Author(s):  
Patrı́cia A Mörking ◽  
Bruno M Dallagiovanna ◽  
Leonardo Foti ◽  
Beatriz Garat ◽  
Gisele F.A Picchi ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Ccch Zinc Finger ◽  
Finger Protein
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