scholarly journals Type of Proton‐Pump Inhibitor and Risk of Iron Deficiency in Kidney Transplant Recipients – Results from the TransplantLines Biobank and Cohort Study

2021 ◽  
Author(s):  
Rianne M. Douwes ◽  
Joanna Sophia J. Vinke ◽  
António W. Gomes‐Neto ◽  
Gizem Ayerdem ◽  
Gaston van Hassel ◽  
...  
Keyword(s):  
Cohort Study ◽  
Iron Deficiency ◽  
Proton Pump Inhibitor ◽  
Kidney Transplant ◽  
Proton Pump ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients

Associations between Proton Pump Inhibitor and Histamine-2 Receptor Antagonist and Bone Mineral Density among Kidney Transplant Recipients

2020 ◽  
Vol 51 (6) ◽  
pp. 433-441
Author(s):  
Beini Lyu ◽  
Karen E. Hansen ◽  
Margaret R. Jorgenson ◽  
Brad C. Astor
Keyword(s):  
Bone Mineral Density ◽  
Proton Pump Inhibitor ◽  
Receptor Antagonist ◽  
Kidney Transplant ◽  
Bone Mineral ◽  
Proton Pump ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Mineral Density ◽  
T Score

Background: In the general population, use of proton pump inhibitor (PPI) has been linked to higher risk of osteoporotic fractures. PPI is commonly prescribed in kidney transplant recipients (KTRs). However, the effect of PPI on osteoporosis in KTRs is largely unstudied. Methods: A total of 1,774 adult KTRs in the Wisconsin Allograft Recipient Database with at least one eligible bone mineral density (BMD) measurement at least 3 months after transplantation were included in the analyses. Associations between use of PPI and histamine-2 receptor antagonist (H2RA) at 3 months after transplantation and subsequent slope of T-score were assessed. Results: A total of 1,478 (83.3%) participants were using a PPI at 3 months after transplantation. Compared to the use of H2RA, use of PPI was not significantly associated with annualized slope of hip T-score (β = –0.0039, 95% CI –0.00497 to 0.0021) or annualized slope of spine T-score (β = –0.017, 95% CI –0.049 to 0.083) after adjustment for potential confounders. Similarly, no significant association between use of PPI and slope of T-score was observed when defining PPI/H2RA exposure as use within 6 months of the initial BMD measurement, or only including participants with at least 2 BMD measurements, or stratified by different age and sex. Conclusions: Use of PPI was not associated with an increased rate of BMD loss in KTRs. Our results support previous findings that PPI use does not have a significant effect on bone mineral loss.

scholarly journals Proton Pump Inhibitor Use and Risk of Hip Fracture in Kidney Transplant Recipients

2017 ◽  
Vol 69 (5) ◽  
pp. 595-601 ◽  
Author(s):  
Colin R. Lenihan ◽  
Sumi Sukumaran Nair ◽  
Chandan Vangala ◽  
Venkat Ramanathan ◽  
Maria E. Montez-Rath ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Proton Pump Inhibitor ◽  
Kidney Transplant ◽  
Proton Pump ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients

scholarly journals Induction immunosuppression and the risk of incident malignancies among older and younger kidney transplant recipients: A prospective cohort study

2020 ◽  
Vol 34 (12) ◽  
Author(s):  
Lingyu Wang ◽  
Jennifer Motter ◽  
Sunjae Bae ◽  
JiYoon B. Ahn ◽  
Jennifer A. Kanakry ◽  
...  
Keyword(s):  
Cohort Study ◽  
Kidney Transplant ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients

Incidence of cancer in kidney-transplant recipients: A long-term cohort study in a single center

2011 ◽  
Vol 35 (2) ◽  
pp. 105-111 ◽  
Author(s):  
Hermina C. Wisgerhof ◽  
Lydia G.M. van der Geest ◽  
Johan W. de Fijter ◽  
Geert W. Haasnoot ◽  
Frans H.J. Claas ◽  
...  
Keyword(s):  
Cohort Study ◽  
Kidney Transplant ◽  
Transplant Recipients ◽  
Single Center ◽  
Kidney Transplant Recipients ◽  
Incidence Of Cancer

Vitamin D deficiency and infection risk in kidney transplant recipients: A single-center cohort study

2018 ◽  
Vol 20 (6) ◽  
pp. e12988 ◽  
Author(s):  
Mario Fernández-Ruiz ◽  
Laura Corbella ◽  
Alejandra Morales-Cartagena ◽  
Esther González ◽  
Natalia Polanco ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Vitamin D Deficiency ◽  
Kidney Transplant ◽  
Infection Risk ◽  
Transplant Recipients ◽  
Single Center ◽  
Kidney Transplant Recipients
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