Pilot study using five methods to evaluate skin barrier function in healthy dogs and in dogs with atopic dermatitis

2019 ◽  
Vol 30 (2) ◽  
pp. 121-e34 ◽  
Author(s):  
Danielle Cobiella ◽  
Linda Archer ◽  
Mary Bohannon ◽  
Domenico Santoro
Keyword(s):  
Atopic Dermatitis ◽  
Pilot Study ◽  
Barrier Function ◽  
Skin Barrier ◽  
Skin Barrier Function ◽  
Healthy Dogs

16437 Effects of cleansing on skin barrier function in atopic dermatitis and healthy skin: A pilot study

2020 ◽  
Vol 83 (6) ◽  
pp. AB63
Author(s):  
Aleksi J. Hendricks ◽  
Bryan W. Kromenacker ◽  
Alyssa Thompson ◽  
Elizabeth I. Mata ◽  
Catherine M. Ludwig ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Pilot Study ◽  
Barrier Function ◽  
Skin Barrier ◽  
Skin Barrier Function ◽  
Healthy Skin

Ultra-pure soft water improves skin barrier function in children with atopic dermatitis: A randomized, double-blind, placebo-controlled, crossover pilot study

2014 ◽  
Vol 76 (3) ◽  
pp. 269-271 ◽  
Author(s):  
Yaei Togawa ◽  
Naotomo Kambe ◽  
Naoki Shimojo ◽  
Taiji Nakano ◽  
Yasunori Sato ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Pilot Study ◽  
Barrier Function ◽  
Skin Barrier ◽  
Soft Water ◽  
Skin Barrier Function ◽  
Double Blind ◽  
Double Blind Placebo

Skin Barrier Function Repair Is the Next Step in Atopic Dermatitis Treatment

2006 ◽  
Vol 37 (11) ◽  
pp. 19
Author(s):  
DAMIAN MCNAMARA
Keyword(s):  
Atopic Dermatitis ◽  
Barrier Function ◽  
Skin Barrier ◽  
Skin Barrier Function

Instrumental evaluation of skin barrier function and clinical outcomes during dupilumab treatment for atopic dermatitis: An observational study

2021 ◽  
Author(s):  
Antonio Cristaudo ◽  
Flavia Pigliacelli ◽  
Francesca Sperati ◽  
Diego Orsini ◽  
Norma Cameli ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Observational Study ◽  
Clinical Outcomes ◽  
Barrier Function ◽  
Skin Barrier ◽  
Skin Barrier Function ◽  
Instrumental Evaluation

scholarly journals Skin Barrier Function in Psoriasis and Atopic Dermatitis: Transepidermal Water Loss and Temperature as Useful Tools to Assess Disease Severity

2021 ◽  
Vol 10 (2) ◽  
pp. 359 ◽  
Author(s):  
Trinidad Montero-Vilchez ◽  
María-Victoria Segura-Fernández-Nogueras ◽  
Isabel Pérez-Rodríguez ◽  
Miguel Soler-Gongora ◽  
Antonio Martinez-Lopez ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Disease Severity ◽  
Water Loss ◽  
Barrier Function ◽  
Skin Barrier ◽  
Transepidermal Water Loss ◽  
Diagnostic Tools ◽  
Psoriatic Skin ◽  
Skin Barrier Function ◽  
Healthy Controls

Multiple diagnostic tools are used to evaluate psoriasis and atopic dermatitis (AD) severity, but most of them are based on subjective components. Transepidermal water loss (TEWL) and temperature are skin barrier function parameters that can be objectively measured and could help clinicians to evaluate disease severity accurately. Thus, the aims of this study are: (1) to compare skin barrier function between healthy skin, psoriatic skin and AD skin; and (2) to assess if skin barrier function parameters could predict disease severity. A cross-sectional study was designed, and epidermal barrier function parameters were measured. The study included 314 participants: 157 healthy individuals, 92 psoriatic patients, and 65 atopic dermatitis patients. TEWL was significantly higher, while stratum corneum hydration (SCH) (8.71 vs. 38.43 vs. 44.39 Arbitrary Units (AU)) was lower at psoriatic plaques than at uninvolved psoriatic skin and healthy controls. Patients with both TEWL > 13.85 g·m−2h−1 and temperature > 30.85 °C presented a moderate/severe psoriasis (psoriasis area severity index (PASI) ≥ 7), with a specificity of 76.3%. TEWL (28.68 vs. 13.15 vs. 11.60 g·m−2 h−1) and temperature were significantly higher, while SCH (25.20 vs. 40.95 vs. 50.73 AU) was lower at AD eczematous lesions than uninvolved AD skin and healthy controls. Patients with a temperature > 31.75 °C presented a moderate/severe AD (SCORing Atopic Dermatitis (SCORAD) ≥ 37) with a sensitivity of 81.8%. In conclusion, temperature and TEWL values may help clinicians to determine disease severity and select patients who need intensive treatment.

Correlation of clinical features and skin barrier function in adolescent and adult patients with atopic dermatitis

2006 ◽  
Vol 45 (6) ◽  
pp. 698-701 ◽  
Author(s):  
Do-Won Kim ◽  
Jee-Young Park ◽  
Gun-Yoen Na ◽  
Seok-Jong Lee ◽  
Weon-Ju Lee
Keyword(s):  
Atopic Dermatitis ◽  
Clinical Features ◽  
Barrier Function ◽  
Skin Barrier ◽  
Adult Patients ◽  
Skin Barrier Function
Sign in / Sign up

Export Citation Format

Share Document