Standardized capillary refill time and relation to clinical parameters in hospitalized dogs

2021 ◽  
Author(s):  
Nolan V. Chalifoux ◽  
Carl F. Spielvogel ◽  
Darko Stefanovski ◽  
Deborah C. Silverstein
Keyword(s):  
Clinical Parameters ◽  
Capillary Refill Time ◽  
Capillary Refill

Effect of acupuncture on capillary refill time in healthy adults: A clinical study

2021 ◽  
Vol 135 ◽  
pp. 104135
Author(s):  
Bo-Yan Yeh ◽  
Yen-Lin Chao ◽  
Yu-Sheng Chen ◽  
Huang-Ping Yu
Keyword(s):  
Clinical Study ◽  
Healthy Adults ◽  
Capillary Refill Time ◽  
Capillary Refill

scholarly journals Effects of capillary refill time-vs. lactate-targeted fluid resuscitation on regional, microcirculatory and hypoxia-related perfusion parameters in septic shock: a randomized controlled trial

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Ricardo Castro ◽  
Eduardo Kattan ◽  
Giorgio Ferri ◽  
Ronald Pairumani ◽  
Emilio Daniel Valenzuela ◽  
...  
Keyword(s):  
Septic Shock ◽  
Randomized Controlled Trial ◽  
Fluid Resuscitation ◽  
Controlled Trial ◽  
Tissue Perfusion ◽  
Capillary Refill Time ◽  
Capillary Refill ◽  
Randomized Controlled ◽  
Microcirculatory Flow ◽  
The Impact

Abstract Background Persistent hyperlactatemia has been considered as a signal of tissue hypoperfusion in septic shock patients, but multiple non-hypoperfusion-related pathogenic mechanisms could be involved. Therefore, pursuing lactate normalization may lead to the risk of fluid overload. Peripheral perfusion, assessed by the capillary refill time (CRT), could be an effective alternative resuscitation target as recently demonstrated by the ANDROMEDA-SHOCK trial. We designed the present randomized controlled trial to address the impact of a CRT-targeted (CRT-T) vs. a lactate-targeted (LAC-T) fluid resuscitation strategy on fluid balances within 24 h of septic shock diagnosis. In addition, we compared the effects of both strategies on organ dysfunction, regional and microcirculatory flow, and tissue hypoxia surrogates. Results Forty-two fluid-responsive septic shock patients were randomized into CRT-T or LAC-T groups. Fluids were administered until target achievement during the 6 h intervention period, or until safety criteria were met. CRT-T was aimed at CRT normalization (≤ 3 s), whereas in LAC-T the goal was lactate normalization (≤ 2 mmol/L) or a 20% decrease every 2 h. Multimodal perfusion monitoring included sublingual microcirculatory assessment; plasma-disappearance rate of indocyanine green; muscle oxygen saturation; central venous-arterial pCO2 gradient/ arterial-venous O2 content difference ratio; and lactate/pyruvate ratio. There was no difference between CRT-T vs. LAC-T in 6 h-fluid boluses (875 [375–2625] vs. 1500 [1000–2000], p = 0.3), or balances (982[249–2833] vs. 15,800 [740–6587, p = 0.2]). CRT-T was associated with a higher achievement of the predefined perfusion target (62 vs. 24, p = 0.03). No significant differences in perfusion-related variables or hypoxia surrogates were observed. Conclusions CRT-targeted fluid resuscitation was not superior to a lactate-targeted one on fluid administration or balances. However, it was associated with comparable effects on regional and microcirculatory flow parameters and hypoxia surrogates, and a faster achievement of the predefined resuscitation target. Our data suggest that stopping fluids in patients with CRT ≤ 3 s appears as safe in terms of tissue perfusion. Clinical Trials: ClinicalTrials.gov Identifier: NCT03762005 (Retrospectively registered on December 3rd 2018)

Reliability of capillary refill time for evaluation of tissue perfusion in simulated vascular occluded limbs

2021 ◽  
Author(s):  
Yuwarat Monteerarat ◽  
Roongsak Limthongthang ◽  
Panai Laohaprasitiporn ◽  
Torpon Vathana
Keyword(s):  
Tissue Perfusion ◽  
Capillary Refill Time ◽  
Capillary Refill

The agreement of fingertip and sternum capillary refill time in children

2013 ◽  
Vol 98 (4) ◽  
pp. 265-268 ◽  
Author(s):  
J. Crook ◽  
R. M. Taylor
Keyword(s):  
Capillary Refill Time ◽  
Capillary Refill

The association between capillary refill time and arterial flow in the pediatric upper extremity

2008 ◽  
Vol 17 (5) ◽  
pp. 257-260 ◽  
Author(s):  
Katherine Gray ◽  
Michael R. Briseno ◽  
Norman Y. Otsuka
Keyword(s):  
Upper Extremity ◽  
Arterial Flow ◽  
Capillary Refill Time ◽  
Capillary Refill

Measurement of capillary refill time with a handheld prototype device: a comparative validation study in healthy volunteers

2021 ◽  
Author(s):  
M. Ruste ◽  
L. Cazenave ◽  
M. Tardif ◽  
C. Saint-Jean ◽  
J.-L. Fellahi ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Validation Study ◽  
Capillary Refill Time ◽  
Capillary Refill ◽  
Prototype Device ◽  
Comparative Validation

A Novel Imaging Technique to Measure Capillary-Refill Time: Improving Diagnostic Accuracy for Dehydration in Young Children With Gastroenteritis

PEDIATRICS ◽  
2006 ◽  
Vol 118 (6) ◽  
pp. 2402-2408 ◽  
Author(s):  
I. Shavit ◽  
R. Brant ◽  
C. Nijssen-Jordan ◽  
R. Galbraith ◽  
D. W. Johnson
Keyword(s):  
Young Children ◽  
Diagnostic Accuracy ◽  
Imaging Technique ◽  
Capillary Refill Time ◽  
Capillary Refill

Comparison of peripheral and central capillary refill time in febrile children presenting to a paediatric emergency department and its utility in identifying children with serious bacterial infection

2016 ◽  
Vol 102 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Evelien de Vos-Kerkhof ◽  
Tarik Krecinic ◽  
Yvonne Vergouwe ◽  
Henriëtte A Moll ◽  
Ruud G Nijman ◽  
...  
Keyword(s):  
Emergency Department ◽  
Body Temperature ◽  
General Population ◽  
Bacterial Infection ◽  
Capillary Refill Time ◽  
Radiographic Findings ◽  
Capillary Refill ◽  
Clinical Criteria ◽  
Paediatric Emergency Department ◽  
Paediatric Emergency

ObjectiveTo determine the agreement between peripheral and central capillary refill time (pCRT/cCRT) and their diagnostic values for detecting serious bacterial infection (SBI) in febrile children attending the paediatric emergency department (ED).DesignProspective observational study.SettingPaediatric ED, Erasmus Medium Care-Sophia Children's hospital, the Netherlands.Patients1193 consecutively included, previously healthy, febrile children (1 month–16 years) with both pCRT measurements and cCRT measurements available. SBI diagnosis was based on abnormal radiographic findings and/or positive cultures from normally sterile locations in addition to clinical criteria.Main outcome measuresAgreement between pCRT and cCRT (Cohen's κ), overall and stratified for age and body temperature. The diagnostic value of pCRT and cCRT for SBI was assessed with logistic regression.ResultsOverall agreement was 0.35 (95% CI 0.27 to 0.43; considered ‘fair’). Although not significant, agreement was lower in children aged 1–<5 years (κ: 0.15 (95% CI 0.04 to 0.27)) and decreased with higher body temperatures with κ ranging from 0.55 (95% CI 0.32 to 0.79) for temperature <37.5°C to 0.21 (95% CI 0.07 to 0.34) for temperature >39.5°C. Abnormal pCRT (>2 s) was observed in 153 (12.8%; 95% CI 10.9% to 14.7%) and abnormal cCRT in 55 (4.6%; 95% CI 3.4% to 5.8%) children. The OR of abnormal pCRT (>2 s) for predicting SBI was 1.10 (95% CI 0.65 to 1.84). For abnormal cCRT (>2 s), the OR was 0.43 (95% CI 0.13 to 1.39).ConclusionsThe pCRT and cCRT values showed only fair agreement in a general population of febrile children at the ED, and no significant association with age or body temperature was found. Only a small part of febrile children at risk for serious infections at the ED show abnormal CRT values. Both abnormal pCRT and cCRT (defined as >2 s) performed poorly and were non-significant in this study detecting SBI in a general population of febrile children.

scholarly journals Skin mottling score and capillary refill time to assess mortality of septic shock since pre-hospital setting

2019 ◽  
Vol 37 (4) ◽  
pp. 664-671 ◽  
Author(s):  
Romain Jouffroy ◽  
Anastasia Saade ◽  
Jean Pierre Tourtier ◽  
Papa Gueye ◽  
Emmanuel Bloch-Laine ◽  
...  
Keyword(s):  
Septic Shock ◽  
Hospital Setting ◽  
Capillary Refill Time ◽  
Capillary Refill
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