scholarly journals Relationship between corneal sensitivity, corneal thickness, corneal diameter, and intraocular pressure in normal cats and cats with congenital glaucoma

2018 ◽  
Vol 22 (1) ◽  
pp. 4-12 ◽  
Author(s):  
Mary R. Telle ◽  
Nickolas Chen ◽  
Daniel Shinsako ◽  
Julie A. Kiland ◽  
Kazuya Oikawa ◽  
...  
2021 ◽  
Vol 7 (2) ◽  
pp. 385-388
Author(s):  
Gunjan P Tank ◽  
Kamini M Prajapati ◽  
Rupal Bhatt ◽  
Amita Chauhan ◽  
Mariam Mansuri ◽  
...  

To evaluate the effect of intraocular pressure (IOP) on central corneal thickness (CCT), horizontal corneal diameter (HCD), axial length (AL) in patients with primary congenital glaucoma (PCG) after antiglaucoma surgery. In this hospital based interventional study 36 patients (66 eyes) of PCG who underwent antiglaucoma surgery were included in the study. For each patient visual acuity, anterior and posterior segment examination, IOP, AL, CCT, HCD and refraction (in clear media) were recorded pre and post operatively (3 weeks, 3 months, 6 months). B scan ultrasonography was done to measure AL and to rule out posterior segment pathology. Surgery was performed by a glaucoma expert (by a single surgeon). Bilateral involvement was present in 83.33% with the most common symptom being photophobia and watering (30.56% each). The mean IOP, CCT, HCD, VCD and AL before surgery were 26.88+/-2.78 mmHg, 614.38+/-89.41 µ, 14.41+/-1.26mm, 13.19+/-1.46mm and 24.78+/-2.21mm and at 6 months were 13.85+/-1.93 mmHg, 548.56+/-63.13 µ, 14.62+/-0.49 mm, 13.34+/-1.10 mm and 25.73+/-1.36mm respectively. 59.1% of the patients had corneal clearing at 6 months. Control of IOP affects various parameters of eye like CCT, HCD and AL. Early surgery is the definitive line of management for controlling IOP in PCG patients.


2021 ◽  
pp. 112067212110483
Author(s):  
Andrea Oliveira da Silva ◽  
Christiane Rolim-de-Moura ◽  
Nara Lúcia Poli Botelho ◽  
Carolina PB Gracitelli ◽  
Nívea Nunes Ferraz

Purpose: To identify psychosocial indicators and evaluate the filtering surgeries impacts on quality of life (QOL) of children with primary congenital glaucoma (PCG) and their family. Methods: Parents of children with bilateral PCG who underwent filtering surgery were included. Data were collected through: (a) psychological inquiry to determine psychosocial indicators; (b) Children’s Visual Function Questionnaire (CVFQ). The associations between the CVFQ scores and visual acuity, intraocular pressure, optic disk cupping, horizontal corneal diameter, axial length, number of surgeries, and hypotensive eye drops were investigated. The statistical significance level was considered as p ⩽ 0.05. Results: The mean age of the nine mothers interviewed and their children (six boys and three girls) was 29 ± 5 years and 35 ± 18 months, respectively. The psychosocial indicators determined were: emotional impact of the diagnosis, disease knowledge, mother and family’s feelings on facing the surgical treatment, surgical result comprehension, treatment adherence, child's emotional and behavioral reactions, social support, and future expectations. In CVFQ analysis, QOL score was strongly associated with visual acuity ( r = −0.79; p = 0.01). Besides the treatment score was correlated to intraocular pressure ( r = −0.68; p < 0.05), optic disk cupping ( r = −0.85; p = 0.03), and corneal diameter ( r = −0.69; p = 0.02). Correlations were not found for number of surgeries and eye drops. Conclusions: This study confirmed the PCG surgical treatment impact on QOL and determined psychosocial indicators which may favor the suitable actions in psychological treatment and follow-up of the children and families.


2021 ◽  
Vol 10 (3) ◽  
pp. 138-145
Author(s):  
Farideh Sharifipour ◽  
Elahe Arasteh ◽  
Maryam Hajizadeh ◽  
Atefe Mahdian-Rad ◽  
Mohammad Sadegh Mirdehghan

Background: Surgical procedures are used as 1 of the main treatment modalities for pediatric glaucoma, even though progression may occur. In this study, we aimed to investigate the risk factors affecting the progression of pediatric glaucoma.Methods: In this retrospective cohort study, we reviewed the medical records of patients diagnosed with pediatric glaucoma between April 2009 and March 2017. Pediatric glaucoma patients who underwent regular follow-up for at least 1 year were included. Demographics, intraocular pressure (IOP), central corneal thickness (CCT), axial length (AL), cup-to-disc ratio (C/D ratio), corneal diameter, type of glaucoma, age at time ofdiagnosis, and age at surgery were recorded. Progression was defined as an increase in AL > 2 mm, C/D ratio > 0.2, or corneal diameter > 1 mm during 1 year of follow-up.Results: Eighty-three eyes from 46 patients were included: 37 eyes (45%) with primary congenital glaucoma (PCG), 46 eyes (55%) with secondary glaucoma, and 27 of these 83 eyes (32.5%) showed progression. Progression was comparable between eyes with PCG and secondary glaucoma (PCG, 22%; secondary glaucoma, 41%; P = 0.152). Age at the time of diagnosis and age at the time of the first surgery were significantly lower in the eyes with progression (P = 0.046 and 0.012, respectively). The mean ± standard deviation of surgeries in progressed versus non-progressed eyes was 1.88 ± 1.1 versus 1 ± 0.8 (P = 0.015). The frequency of comorbid systemic disease was significantly higher in patients with glaucoma progression (P = 0.043). The progressed and non-progressed eyes were comparable in terms of other demographic characteristics and ocular parameters (allP > 0.05).Conclusions: Pediatric glaucoma patients who were younger at the time of diagnosis and the first glaucoma surgery and those with comorbid systemic disease are at higher risk of glaucoma progression. These findings are useful for clinicians when counseling parents of children with pediatric glaucoma about disease outcomes. However, future prospective studies with larger sample sizes and longer follow-up periods are needed to confirm our findings.


Author(s):  
A.Y. Baranov ◽  
◽  
V.V. Brzheskii ◽  
M.N. Chistyakova ◽  
N.N. Sadovnikova ◽  
...  

Background. Ophthalmic hypertension is one of the most important diagnostic criteria for congenital glaucoma. The «gold standard» for measuring intraocular pressure (IOP) is the applanation tonometry (Maklakov and Goldmann methods). However, the thickness of the central corneal zone has a significant effect on the value of IOP measured by these methods. The aim of this study was to compare the central corneal thickness (CCT) in children with congenital glaucoma and in healthy children. Material and methods. We examined 15 children aged from 7 months to 14 years (22 eyes) with congenital glaucoma. In the healthy children group, 26 subjects from 7 to 17 years old (51 eyes) were examined. CCT was measured in all subjects using the optical coherence tomograph Carl Zeiss Cirrus HD-OCT 5000 with an external lens for cornea scanning. The examination was carried out in pachymetry mode; the average thickness of the central ring having a diameter of 2 mm was evaluated. Results. Central corneal thickness in children with glaucoma ranged from 471 to 771 microns, the average value was 561.5±72.26 microns. In the group of healthy children, CCT was in the range of 480-597 microns with an average value of 529.88±29.33 microns. Thus, we noted a higher average value of the central corneal thickness and its higher variability in children with glaucoma in comparison with the group of healthy children. Conclusion. All children with glaucoma and suspected glaucoma should routinely perform pachymetry prior to applanation tonometry. One should consider the central corneal thickness when assessing intraocular pressure. Key words: congenital glaucoma, pachymetry, optical coherence tomography, central corneal thickness, applanation tonometry, intraocular pressure.


1970 ◽  
Vol 20 (1) ◽  
pp. 64-66
Author(s):  
MI Bari ◽  
ME Hoque ◽  
T Alam ◽  
KM Choudhury

A case of preterm neonate with congenital thyrotoxicosis associated with congenital glaucoma is reported. Her mother had undiagnosed thyrotoxicosis. The diagnosis of thyrotoxicosis in the neonate was confirmed by an elevated serum tri-iodothyronine (T3) level of 8.09 nmol/L, thyroxin (T4) level of 3.09 nmol and thyroid stimulating hormone (TSH) level 0.16mu/L. Congenital glaucoma was confirmed by increased intraocular pressure (IOP) which was 42.1 mmHg in right eye and 38.2 mm Hg in left eye. Corneal diameter was increased which was 13 mm in both eyes. Corneal oedema and Haab striae were also present. Probably, this is the first case of congenital thyrotoxicosis associated with congenital glaucoma reported in Bangladesh.   doi: 10.3329/taj.v20i1.3094 TAJ 2007; 20(1): 64-66


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maddalena De Bernardo ◽  
Giulio Salerno ◽  
Marco Gioia ◽  
Luigi Capasso ◽  
Maria Claudia Russillo ◽  
...  

AbstractTo evaluate intraocular pressure (IOP) and choroidal thickness (ChT) postural changes in multiple system atrophy (MSA), Parkinson’s disease (PD) patients and healthy controls (HC). 20 MSA patients, 21 PD patients and 14 HC, were examined. All subjects underwent a complete examination, including corneal thickness, ChT, IOP and axial length (AL) measurements. IOP measurement was performed in supine, sitting, and standing positions, whereas ChT in sitting and standing positions. Supine to standing IOP variations were significantly higher in MSA vs PD(p = 0.01) and in MSA vs HC (p < 0.0001), whereas no significant differences were observed between PD and HC (p = 0.397). Mean sub-foveal ChT in MSA was 240 ± 92 μm in sitting position, and 215 ± 94 μm in standing position with a significant reduction (p = 0.008). Mean sub-foveal ChT in PD was 258 ± 79 μm in sitting position, and 259 ± 76 μm in standing position (p = 0.887). In HC it was 244 ± 36 μm in sitting position, and 256 ± 37 μm in standing position with a significant increase (p = 0.007). The significant IOP and ChT postural changes can be considered additional hallmarks of autonomic dysfunction in MSA and further studies are needed to consider them as biomarkers in the differential diagnosis with PD.


Sign in / Sign up

Export Citation Format

Share Document