scholarly journals To evaluate effect of intraocular pressure control on central corneal thickness, horizontal corneal diameter and axial length in primary congenital glaucoma

2021 ◽  
Vol 7 (2) ◽  
pp. 385-388
Author(s):  
Gunjan P Tank ◽  
Kamini M Prajapati ◽  
Rupal Bhatt ◽  
Amita Chauhan ◽  
Mariam Mansuri ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Axial Length ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Pressure Control ◽  
Posterior Segment ◽  
Congenital Glaucoma ◽  
Common Symptom ◽  
Primary Congenital Glaucoma ◽  
Corneal Diameter

To evaluate the effect of intraocular pressure (IOP) on central corneal thickness (CCT), horizontal corneal diameter (HCD), axial length (AL) in patients with primary congenital glaucoma (PCG) after antiglaucoma surgery. In this hospital based interventional study 36 patients (66 eyes) of PCG who underwent antiglaucoma surgery were included in the study. For each patient visual acuity, anterior and posterior segment examination, IOP, AL, CCT, HCD and refraction (in clear media) were recorded pre and post operatively (3 weeks, 3 months, 6 months). B scan ultrasonography was done to measure AL and to rule out posterior segment pathology. Surgery was performed by a glaucoma expert (by a single surgeon). Bilateral involvement was present in 83.33% with the most common symptom being photophobia and watering (30.56% each). The mean IOP, CCT, HCD, VCD and AL before surgery were 26.88+/-2.78 mmHg, 614.38+/-89.41 µ, 14.41+/-1.26mm, 13.19+/-1.46mm and 24.78+/-2.21mm and at 6 months were 13.85+/-1.93 mmHg, 548.56+/-63.13 µ, 14.62+/-0.49 mm, 13.34+/-1.10 mm and 25.73+/-1.36mm respectively. 59.1% of the patients had corneal clearing at 6 months. Control of IOP affects various parameters of eye like CCT, HCD and AL. Early surgery is the definitive line of management for controlling IOP in PCG patients.

Effect of intraocular pressure control on central corneal thickness, horizontal corneal diameter, and axial length in primary congenital glaucoma

2014 ◽  
Vol 18 (5) ◽  
pp. 433-436 ◽  
Author(s):  
Sebastião Cronemberger ◽  
Nassim Calixto ◽  
Thiago Gutemberg Avellar Milhomens ◽  
Priscila Ottoni Gama ◽  
Eduardo Gutemberg Milhomens ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Axial Length ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Pressure Control ◽  
Congenital Glaucoma ◽  
Primary Congenital Glaucoma ◽  
Corneal Diameter

scholarly journals Effects of SMILE Surgery on Intraocular Pressure, Central Corneal Thickness, Axial Length, Peripapillary Retinal Nerve Fiber Layer, and Macular Ganglion Cell Complex Thickness

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Zhanlin Zhao ◽  
Sylvain Michée ◽  
Jean-François Faure ◽  
Christophe Baudouin ◽  
Antoine Labbé
Keyword(s):  
Intraocular Pressure ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Axial Length ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Ganglion Cell Complex ◽  
Fiber Layer ◽  
Rnfl Thickness ◽  
The Mean

Purpose. To evaluate the change in intraocular pressure (IOP), central corneal thickness (CCT), axial length, peripapillary retinal nerve fiber layer (RNFL) thickness, and macular ganglion cell complex (GCC) thickness after small incision lenticule extraction (SMILE) surgery. Methods. This prospective observational study was conducted in Espace Nouvelle Vision, Ophthalmological Clinic, Paris, France. Fifty eyes of 25 patients were enrolled in this study and underwent SMILE surgeries. IOP, central corneal thickness (CCT), axial length (AL), peripapillary RNFL thickness, and macular GCC thickness were measured before and at 3 months after SMILE. Results. The mean preoperative spherical equivalent was −3.15 ± 1.50 diopters (D), and the mean postoperative value was 0.15 ± 0.28 D. After SMILE surgery, IOP decreased from 15.03 ± 2.79 mmHg to 11.02 ± 2.73 mmHg and 10.02 ± 2.21 mmHg at 1 and 3 months, respectively ( P < 0.01 for both comparisons). The mean decrease in measured IOP as a function of ablation depth was 0.065 ± 0.031 mmHg/μm. CCT decreased from 545.98 ± 26.61 μm to 478.40 ± 30.26 μm after SMILE surgery ( P < 0.01 ). AL decreased from 24.80 ± 0.84 mm to 24.70 ± 0.83 mm ( P < 0.01 ). There was no statistically significant change in mean peripapillary RNFL or mean GCC thickness after SMILE surgery. Conclusions. SMILE surgery modified IOP measurement, CCT, and AL but did not change peripapillary RNFL and macular GCC thicknesses. The postoperative drop in measured IOP might be explained by the decreased CCT. An accurate re-evaluation of AL should be performed before cataract surgery among post-SMILE patients.

Psychosocial indicators of primary congenital glaucoma and filtering surgeries impacts on children and family’s quality of life

2021 ◽  
pp. 112067212110483
Author(s):  
Andrea Oliveira da Silva ◽  
Christiane Rolim-de-Moura ◽  
Nara Lúcia Poli Botelho ◽  
Carolina PB Gracitelli ◽  
Nívea Nunes Ferraz
Keyword(s):  
Quality Of Life ◽  
Visual Acuity ◽  
Intraocular Pressure ◽  
Surgical Treatment ◽  
Optic Disk ◽  
Congenital Glaucoma ◽  
Eye Drops ◽  
Primary Congenital Glaucoma ◽  
Corneal Diameter

Purpose: To identify psychosocial indicators and evaluate the filtering surgeries impacts on quality of life (QOL) of children with primary congenital glaucoma (PCG) and their family. Methods: Parents of children with bilateral PCG who underwent filtering surgery were included. Data were collected through: (a) psychological inquiry to determine psychosocial indicators; (b) Children’s Visual Function Questionnaire (CVFQ). The associations between the CVFQ scores and visual acuity, intraocular pressure, optic disk cupping, horizontal corneal diameter, axial length, number of surgeries, and hypotensive eye drops were investigated. The statistical significance level was considered as p ⩽ 0.05. Results: The mean age of the nine mothers interviewed and their children (six boys and three girls) was 29 ± 5 years and 35 ± 18 months, respectively. The psychosocial indicators determined were: emotional impact of the diagnosis, disease knowledge, mother and family’s feelings on facing the surgical treatment, surgical result comprehension, treatment adherence, child's emotional and behavioral reactions, social support, and future expectations. In CVFQ analysis, QOL score was strongly associated with visual acuity ( r = −0.79; p = 0.01). Besides the treatment score was correlated to intraocular pressure ( r = −0.68; p < 0.05), optic disk cupping ( r = −0.85; p = 0.03), and corneal diameter ( r = −0.69; p = 0.02). Correlations were not found for number of surgeries and eye drops. Conclusions: This study confirmed the PCG surgical treatment impact on QOL and determined psychosocial indicators which may favor the suitable actions in psychological treatment and follow-up of the children and families.

scholarly journals The relationship between axial length, age and intraocular pressure in children with primary congenital glaucoma

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Ibrahim Al-Obaida ◽  
Adi Mohammed Al Owaifeer ◽  
Khabir Ahmad ◽  
Rizwan Malik
Keyword(s):  
Intraocular Pressure ◽  
Axial Length ◽  
Care Facility ◽  
Glaucoma Surgery ◽  
Clinical Parameter ◽  
Congenital Glaucoma ◽  
Primary Congenital Glaucoma ◽  
Number Of Children ◽  
Predicted Values ◽  
The Relationship

Abstract Whilst axial length (AxL) from ultrasound examination is a useful clinical parameter for monitoring progression in younger children with glaucoma, distinguishing AxL changes due to raised intraocular pressure (IOP) from age is often challenging. Existing normograms have included a limited number of children with glaucoma. The aim of this study was to evaluate the relationship between AxL with age and IOP in children with primary congenital glaucoma (PCG) and develop a model for expected AxL increase with age. All children (n = 208; 397 eyes) with PCG who attended our tertiary eye care facility from June 2014 and July 2018 and had AxL and IOP measurements were included. The relationship of AxL with age and IOP was studied by applying a LOWESS fit and then mixed effects models. In the final model, age was the most significant factor influencing the growth of AxL (coefficient age 3.14[95% CI 2.91–3.35, p < 0.001], coefficient age2 − 0.53[95% CI, − 0.59 to − 0.47, p < 0.001]), and this association was influenced by the interaction of IOP with sex (p = 0.098 for girls relative to boys), the number of antiglaucoma medications (AGM [p < 0.001 for ≥ 3 AGM]) and glaucoma surgery (p = 0.015). This model enabled us to derive predicted values for clinical use in children with PCG to predict those with progressive glaucoma.

scholarly journals Trabeculectomy in Congenital Glaucoma; Experience in Helpers Eye Hospital Quetta

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Mahtab Mengal ◽  
M Afzal Khan ◽  
Aimal Khan ◽  
Manzoor Ahmed ◽  
Rabia Khawar Chaudhry ◽  
...  
Keyword(s):  
General Anesthesia ◽  
Trauma Surgery ◽  
Case Series ◽  
Posterior Segment ◽  
Congenital Glaucoma ◽  
Primary Congenital Glaucoma ◽  
Effective Operation ◽  
Operative Complications ◽  
Corneal Diameter

Purpose: To evaluate outcomes of trabeculectomy in terms of IOP control and its safety in terms of peroperativeand post-operative complications in Primary Congenital Glaucoma.Study Design: Interventional Case-Series.Place and Duration of Study: Helpers Eye Hospital, Quetta, from June 2017 to December 2018.Material and Methods: Thirty eyes of 17 patients were included in this case series after diagnosis of primarycongenital glaucoma. Patients with secondary congenital glaucoma due to trauma, surgery, inflammation, SturgeWeber Syndrome, Neurofibromatosis, cataract, uveitis, aphakia and pseudophakia were excluded from the study.Informed consent was taken from parents. Examination under anesthesia was done before surgery to recordpreoperative IOP, corneal diameter and anterior and posterior segment abnormalities. Primary trabeculectomywas done. Post-operative IOP and corneal diameter was recorded at 1st, 3rd and 6th month and every 6 monthsthereafter under general anesthesia. IOP at 12th month of surgery was the final outcome which was consideredsignificant if IOP was less than 21 mm Hg with stable corneal diameters.Results: Mean preoperative IOP was 25.8 mm Hg. Twenty-three (76.66%) eyes out of 30 eyes were consideredsuccessful with mean IOP of 15.3 mm Hg at last follow-up while 7 (23.33%) cases of failure were observed withpostoperative mean IOP of 27.71 mm Hg. These patients underwent additional surgeries to control IOP.Hyphema was the only complication observed in this study. Postoperative cataract developed in 5 eyes.Conclusion: Primary trabeculectomy is an effective operation and safe surgery for primary congenital glaucoma

scholarly journals Analysis of the horizontal corneal diameter, central corneal thickness, and axial length in premature infants

2014 ◽  
Vol 77 (4) ◽  
Author(s):  
Ozdemir Ozdemir ◽  
Zuhal Özen Tunay ◽  
Ikbal Seza Petriçli ◽  
Damla Ergintürk Acar ◽  
Ugur Acar ◽  
...  
Keyword(s):  
Premature Infants ◽  
Axial Length ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Corneal Diameter

Characteristic of the central cornea thickness in healthy children and in patients with congenital glaucoma

2021 ◽  
pp. 161-163
Author(s):  
A.Y. Baranov ◽  
◽  
V.V. Brzheskii ◽  
M.N. Chistyakova ◽  
N.N. Sadovnikova ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Applanation Tonometry ◽  
Congenital Glaucoma ◽  
Healthy Children ◽  
Optical Coherence ◽  
Average Value ◽  
Cornea Thickness ◽  
Optical Coherence Tomograph

Background. Ophthalmic hypertension is one of the most important diagnostic criteria for congenital glaucoma. The «gold standard» for measuring intraocular pressure (IOP) is the applanation tonometry (Maklakov and Goldmann methods). However, the thickness of the central corneal zone has a significant effect on the value of IOP measured by these methods. The aim of this study was to compare the central corneal thickness (CCT) in children with congenital glaucoma and in healthy children. Material and methods. We examined 15 children aged from 7 months to 14 years (22 eyes) with congenital glaucoma. In the healthy children group, 26 subjects from 7 to 17 years old (51 eyes) were examined. CCT was measured in all subjects using the optical coherence tomograph Carl Zeiss Cirrus HD-OCT 5000 with an external lens for cornea scanning. The examination was carried out in pachymetry mode; the average thickness of the central ring having a diameter of 2 mm was evaluated. Results. Central corneal thickness in children with glaucoma ranged from 471 to 771 microns, the average value was 561.5±72.26 microns. In the group of healthy children, CCT was in the range of 480-597 microns with an average value of 529.88±29.33 microns. Thus, we noted a higher average value of the central corneal thickness and its higher variability in children with glaucoma in comparison with the group of healthy children. Conclusion. All children with glaucoma and suspected glaucoma should routinely perform pachymetry prior to applanation tonometry. One should consider the central corneal thickness when assessing intraocular pressure. Key words: congenital glaucoma, pachymetry, optical coherence tomography, central corneal thickness, applanation tonometry, intraocular pressure.

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