scholarly journals Purinergic modulation of chemosensory drive to breathe from the lateral hypothalamus/perifornical area depends upon sleep-wake and light-dark phases

2018 ◽  
Vol 103 (12) ◽  
pp. 1575-1576
Author(s):  
David P. Burns ◽  
Ken D. O'Halloran
Keyword(s):  
Lateral Hypothalamus ◽  
Purinergic Modulation

scholarly journals Research progress on the mechanism of orexin in pain regulation in different brain regions

2021 ◽  
Vol 16 (1) ◽  
pp. 46-52
Author(s):  
Xianhui Kang ◽  
Hongli Tang ◽  
Yao Liu ◽  
Yan Yuan ◽  
Mi Wang
Keyword(s):  
Energy Metabolism ◽  
Acute Pain ◽  
Lateral Hypothalamus ◽  
Brain Regions ◽  
Cardiovascular Control ◽  
Research Progress ◽  
Orexin A ◽  
Physiological Functions ◽  
Pain Transmission ◽  
Pain Regulation

Abstract Orexin is a neuropeptide that is primarily synthesized and secreted by the lateral hypothalamus (LH) and includes two substances derived from the same precursor (orexin A [OXA] and orexin B [OXB]). Studies have shown that orexin is not only involved in the regulation of eating, the sleep–wake cycle, and energy metabolism, but also closely associated with various physiological functions, such as cardiovascular control, reproduction, stress, reward, addiction, and the modulation of pain transmission. At present, studies that have been performed both domestically and abroad have confirmed that orexin and its receptors are closely associated with pain regulation. In this article, the research progress on acute pain regulation involving orexin is reviewed.

Sign in / Sign up

Export Citation Format

Share Document