Groove Formation Modeling in Fabricating Hollow Fiber Membrane for Nerve Regeneration

2010 ◽  
Vol 78 (1) ◽  
Author(s):  
Jun Yin ◽  
Nicole Coutris ◽  
Yong Huang
Keyword(s):  
Nerve Regeneration ◽  
Hollow Fiber ◽  
Phase Inversion ◽  
Hollow Fiber Membrane ◽  
Nerve Repair ◽  
Industrial Applications ◽  
Elastic Cylindrical Shell ◽  
Fiber Membrane ◽  
Membrane Fabrication ◽  
Recent Interest

Hollow fiber membrane (HFM) is one of the most popular membranes used for different industrial applications. Under some controlled fabrication conditions, axially aligned grooves can be formed on the HFM inner surface during typical immersion precipitation-based phase inversion fabrication processes. Such grooved HFMs are finding promising medical applications for nerve repair and regeneration. For better nerve regeneration performance, the HFM groove morphology should be carefully controlled. Toward this goal, this study has modeled the HFM groove number based on the shrinkage-induced buckling model in HFM fabrication. HFM has been modeled as a three-layer long fiber membrane. The HFM inner layer has been treated as a thin-walled elastic cylindrical shell and buckles due to the shrinkage of the compliant intermediate layer during solidification. The groove geometry, especially the groove number, has been reasonably predicted compared with the experimental measurements. This study has laid a mathematical foundation for HFM circumferential instability modeling, which is of recent interest in membrane fabrication.

Investigation of Inner Surface Groove Formation Under Radially Inward Pressure During Immersion Precipitation-Based Hollow Fiber Membrane Fabrication

2011 ◽  
Vol 133 (3) ◽  
Author(s):  
Jun Yin ◽  
Nicole Coutris ◽  
Yong Huang
Keyword(s):  
Hollow Fiber ◽  
Hollow Fiber Membrane ◽  
Nerve Repair ◽  
Radial Pressure ◽  
Skin Layer ◽  
Elastic Cylindrical Shell ◽  
Fiber Membrane ◽  
Buckling Mode ◽  
Membrane Fabrication ◽  
Inner Surface

Axially aligned grooves can be formed on the hollow fiber membrane (HFM) inner surface under some controlled fabrication conditions during a typical immersion precipitation-based phase inversion fabrication process. Such grooved HFMs are finding promising medical applications for nerve repair and regeneration. For better nerve regeneration performance, the HFM groove geometry should be carefully controlled. Towards this goal, in this study the polyacrylonitrile (PAN) HFM groove number has been modeled based on the radially inward pressure-induced buckling mechanism. HFM has been modeled as a long six-layer fiber membrane, and the HFM inner skin layer has been treated as a thin-walled elastic cylindrical shell under the shrinkage-induced inward radial pressure. The groove number has been reasonably estimated based on the resulting buckling mode as compared with the experimental measurements.

Preparation of Ceramic Hollow Fiber Membrane Using Phase Inversion and Sintering Technique

2016 ◽  
Vol 1133 ◽  
pp. 141-145 ◽  
Author(s):  
Norfazliana Abdullah ◽  
Mukhlis A. Rahman ◽  
A.F. Ismail ◽  
M.H.D. Othman ◽  
Juhana Jaafar
Keyword(s):  
Hollow Fiber ◽  
Phase Inversion ◽  
Hollow Fiber Membrane ◽  
Fabrication Process ◽  
Asymmetric Structure ◽  
Sintering Process ◽  
Fiber Membrane ◽  
Membrane Fabrication ◽  
Phase Inversion Technique ◽  
The Given

Alumina hollow fiber membrane with asymmetric structure has been developed using phase inversion technique followed by sintering process. The formation of asymmetric alumina hollow fiber was influenced by a phenomenon known as hydrodynamically unstable viscous fingering. A desired morphology of the ceramic hollow fiber membrane, that consists of 52 % of finger-like and the rest is sponge-like structure, is tailored by controlled parameters during membrane fabrication process. The result shows that the ratio of alumina/PESf should be reduced to 6. At this ratio, the finger-like structure can be easily formed with inner and outer diameters were 1.11 mm and 2.05 mm respectively. From the given thickness, approximately 243 µm of finger-like length can be developed originating from the lumen of hollow fiber.

scholarly journals Design and characterization of ceramic hollow fiber membrane derived from waste ash using phase inversion-based extrusion/sintering technique for water filtration

2020 ◽  
pp. 1-18
Author(s):  
Zhong Sheng Tai ◽  
Mohd Hafiz Dzarfan Othman ◽  
Azeman Mustafa ◽  
Mohd Irfan Hatim Mohamed Dzahir ◽  
Siti Khadijah Hubadillah ◽  
...  
Keyword(s):  
Hollow Fiber ◽  
Phase Inversion ◽  
Hollow Fiber Membrane ◽  
Water Filtration ◽  
Fiber Membrane

Structure Morphology of Polyethersulfone Hollow Fiber Membrane via Immersion Precipitation Phase Inversion Process

2012 ◽  
Vol 152-154 ◽  
pp. 574-578 ◽  
Author(s):  
Ping Lan ◽  
Wei Wang
Keyword(s):  
Hollow Fiber ◽  
Phase Inversion ◽  
Hollow Fiber Membrane ◽  
Pure Water ◽  
Water Flux ◽  
Additive Concentration ◽  
Hollow Fiber Membranes ◽  
Fiber Membrane ◽  
Fiber Membranes ◽  
And Performance

Polyethersulfone (PES) hollow fiber membranes have been widely used in many fields, such as ultrafiltration, microfiltration, reverse osmosis, liquid/liquid or liquid/solid separation, gas separation, hemodialysis, and so on. In this paper, the sheet PES hollow fiber membranes were prepared. The morphology and performance of membranes can be controlled. By studying the influence of the compositions and conditions on the morphology and performance of PES hollow fiber membrane, the relationship of morphology and performance of the membrane is acquired. The additives were used such as glycerol, BuOH and PEG. In addition, immerse phase inversion was used as membranes preparation method. The morphology of the membrane was controlled by changing kinds of additive, concentration of additive and so on. It was found that the membrane morphologies were changed by additive obviously. Porosity , pure water flux, scanning electron microscopy(SEM) were used to characterize the morphology and performance of the membranes.

Novel thin-film composite tri-bore hollow fiber membrane fabrication for forward osmosis

2014 ◽  
Vol 461 ◽  
pp. 28-38 ◽  
Author(s):  
Lin Luo ◽  
Peng Wang ◽  
Sui Zhang ◽  
Gang Han ◽  
Tai-Shung Chung
Keyword(s):  
Thin Film ◽  
Hollow Fiber ◽  
Hollow Fiber Membrane ◽  
Forward Osmosis ◽  
Fiber Membrane ◽  
Film Composite ◽  
Thin Film Composite ◽  
Membrane Fabrication

The Effects of Nanocrystaline Cellulose on Polysulfone Hollow-Fiber Ultrafiltration Membrane

2012 ◽  
Vol 528 ◽  
pp. 210-213 ◽  
Author(s):  
Xuan Wang ◽  
Hao Long Bai ◽  
Li Ping Zhang
Keyword(s):  
Hollow Fiber ◽  
Phase Inversion ◽  
Hollow Fiber Membrane ◽  
Pure Water ◽  
Water Flux ◽  
Ultrafiltration Membrane ◽  
Fiber Membrane ◽  
Elongation At Break ◽  
Pure Water Flux ◽  
Scaning Electron Microscopy

Nanocrystalline cellulose was used to blend with polysulfone to improve the hydrophicility and mechanical properties of PS hollow fiber ultrafiltration membrane. The method of dry-jet/wet-spining was adopted to form the hollow fiber by the mechanism of phase-inversion. In addition, the content of NCC was increased gradually from 0% to 1 wt% to examin the permeation flux, rejection ratio of bovine serum albumin(BSA) and mechanical strength of PS hollow-fiber. We find that the pure water flux was soared when NCC content was increased. The tensile strength and elongation at break were also detected and calculated. The results indicated that the properties of PS hollow-fiber membrane with appropriate NCC content were enhanced. The hollow fiber membranes were also observed with scaning electron microscopy(SEM) to explore the porous structure

Preparation and characterization of self-cleaning alumina hollow fiber membrane using the phase inversion and sintering technique

2016 ◽  
Vol 42 (10) ◽  
pp. 12312-12322 ◽  
Author(s):  
Norfazliana Abdullah ◽  
Mukhlis A. Rahman ◽  
Mohd Hafiz Dzarfan Othman ◽  
A.F. Ismail ◽  
Juhana Jaafar ◽  
...  
Keyword(s):  
Hollow Fiber ◽  
Phase Inversion ◽  
Hollow Fiber Membrane ◽  
Fiber Membrane ◽  
Self Cleaning

scholarly journals Study on the effect of spinning conditions on the performance of PSf/PVP ultrafiltration hollow fiber membrane

2018 ◽  
Vol 14 (3) ◽  
pp. 343-347 ◽  
Author(s):  
Sumarni Mansur ◽  
Mohd Hafiz Dzarfan Othman ◽  
Ahmad Fauzi Ismail ◽  
Muhammad Nidzhom Zainol Abidin ◽  
Noresah Said ◽  
...  
Keyword(s):  
Pore Size ◽  
Hollow Fiber ◽  
Phase Inversion ◽  
Hollow Fiber Membrane ◽  
Hollow Fibers ◽  
Hollow Fiber Membranes ◽  
Fiber Membrane ◽  
Membrane Pore ◽  
Phase Inversion Technique ◽  
Fiber Membranes

Asymmetric, porous ultrafiltration polysulfone (PSf) hollow fiber membranes were fabricated via the dry-wet phase inversion spinning technique specifically for haemodialysis membrane. The objective was to discover the suitable spinning condition for the fabrication of ultrafiltration hollow fiber membrane with desired sponge-like structure. During haemodialysis procedure, uremic toxins such as urea and creatinine range from size 10,000-55,000 Da needs to be excreted out from the blood. While, proteins such as albumin (66,000 Da) need to be retained. The physical structure or morphology of a fabricated membrane is a major concern in determining the efficiency of a dialysis membrane. Different type of membrane morphology will give a different result in term of its permeability and clearance efficiency. The phase inversion spinning technique is suitable in producing ultrafiltation (UF) membrane where the average pore size of the fabricated membrane is in the range of 0.001 – 0.1 µm. However, there is many factors need to be controlled and manipulated in the phase inversion technique. In this study, the effect of the PVP on membrane pore size and performances were analysed. The contact angle measurement was measured to determine the hydrophilicity of the fibers. The hydrophilic polymer is favorable to avoid fouling and increase its biocompatibility. Furthermore, the diameter of the hollow fibers was determined using a scanning electron microscope (SEM). The effects of different morphology of the hollow fibers on the performance of the membranes were evaluated by pure water flux and BSA rejection. Both techniques were tested using permeation flux system. Based on the results obtained, it is found that the finger-like macrovoids in PSf hollow fiber membranes were suppressed by adding 8% PVP (Mw of 360 kDa) into the spinning dope solution as the result of a drastic increase in dope viscosity. On top of that, fiber spun with 8% PVP show more porous structure which contribute to higher permeability of the membrane. The result of this study can benefit to the membrane field of research especially in membrane technology for haemodialysis application.

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