Real-Time In Situ Compensation for Femtosecond Laser Two-Photon 3D Microfabrication

Author(s):  
Guohua Gao ◽  
Yu Zhu ◽  
Guanghong Duan ◽  
Yingxing Fang ◽  
Xiaoquan Wei

Femtosecond (fs) laser Two-photon Microfabrication is a new real 3D microstructure fabricating method with sub-micron resolution power. In the fabricating process, some factors cause the appearance of the final microstructures different from the design figure. In order to eliminate the appearance error and improve the machining precision, in this paper, two machining defect factors are discussed and real-time in situ compensation is realized based on machine vision monitoring and pattern recognition technique. For the position error induced by the movement error of the 3D micro-displacement scanning stage and the fluid of the liquid resin, one relative distance reference mark system is built to compensate the error. Through the CCD vision monitoring system, at the beginning of every layer fabrication, the 3D scanning stage should be re-posited and ensure the relative positions to the reference marks are right. For the other defect factor, deficient exposure, with the image processing and pattern recognition techniques, the solidified degree of the resin cell can be automatically judged and re-exposure process will be done. This method decreases the accumulative error and is evidently available for the 3D microstructure with larger height value.

2004 ◽  
Vol 139 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Laurea M. Diaz ◽  
Rajani Maiya ◽  
Matthew A. Sullivan ◽  
Yunqing Han ◽  
Heather A. Walton ◽  
...  

2014 ◽  
Vol 86 (18) ◽  
pp. 9131-9138 ◽  
Author(s):  
Hua Zhang ◽  
Jiangli Fan ◽  
Kui Wang ◽  
Jing Li ◽  
Caixia Wang ◽  
...  

2020 ◽  
Vol 56 (90) ◽  
pp. 14007-14010
Author(s):  
Kesong Guan ◽  
Peng Wang ◽  
Fang Zhou ◽  
Youjuan Wang ◽  
Hong-Wen Liu ◽  
...  

We developed a black phosphorus based two-photon fluorescent nanoprobe (TPBP) for the in situ and real-time reporting of the therapeutic response of black phosphorus.


2001 ◽  
Vol 34 (6) ◽  
pp. 399-403 ◽  
Author(s):  
Tomoyuki Kaneko ◽  
Katsumasa Fujita ◽  
Hideo Tanaka ◽  
Masahito Oyamada ◽  
Osamu Nakamura ◽  
...  

2015 ◽  
Vol 51 (74) ◽  
pp. 14022-14025 ◽  
Author(s):  
Hongguang Li ◽  
Rongfeng Lan ◽  
Chi-Fai Chan ◽  
Lijun Jiang ◽  
Lixiong Dai ◽  
...  

A light-responsive antitumor agent, PtEuL, has been synthesized and evaluated for controlled cisplatin release by linear/two-photon excitation in vitro with concomitant turn-on Eu emission as a responsive traceable signal.


2018 ◽  
Author(s):  
Elaine A. Kelly ◽  
Judith E. Houston ◽  
Rachel Evans

Understanding the dynamic self-assembly behaviour of azobenzene photosurfactants (AzoPS) is crucial to advance their use in controlled release applications such as<i></i>drug delivery and micellar catalysis. Currently, their behaviour in the equilibrium <i>cis-</i>and <i>trans</i>-photostationary states is more widely understood than during the photoisomerisation process itself. Here, we investigate the time-dependent self-assembly of the different photoisomers of a model neutral AzoPS, <a>tetraethylene glycol mono(4′,4-octyloxy,octyl-azobenzene) </a>(C<sub>8</sub>AzoOC<sub>8</sub>E<sub>4</sub>) using small-angle neutron scattering (SANS). We show that the incorporation of <i>in-situ</i>UV-Vis absorption spectroscopy with SANS allows the scattering profile, and hence micelle shape, to be correlated with the extent of photoisomerisation in real-time. It was observed that C<sub>8</sub>AzoOC<sub>8</sub>E<sub>4</sub>could switch between wormlike micelles (<i>trans</i>native state) and fractal aggregates (under UV light), with changes in the self-assembled structure arising concurrently with changes in the absorption spectrum. Wormlike micelles could be recovered within 60 seconds of blue light illumination. To the best of our knowledge, this is the first time the degree of AzoPS photoisomerisation has been tracked <i>in</i><i>-situ</i>through combined UV-Vis absorption spectroscopy-SANS measurements. This technique could be widely used to gain mechanistic and kinetic insights into light-dependent processes that are reliant on self-assembly.


2019 ◽  
Vol 10 (6) ◽  
pp. 1382-1394
Author(s):  
R. Vijayalakshmi ◽  
V. K. Soma Sekhar Srinivas ◽  
E. Manjoolatha ◽  
G. Rajeswari ◽  
M. Sundaramurthy

Sign in / Sign up

Export Citation Format

Share Document