Characterization of a megapixel mid-infrared array for high background applications

Author(s):  
A. K. Mainzer ◽  
Henry Hogue ◽  
Maryn Stapelbroek ◽  
Dale Molyneux ◽  
John Hong ◽  
...  
1994 ◽  
Vol 154 ◽  
pp. 595-601
Author(s):  
Daniel Y. Gezari

The anticipated requirements and operating conditions are considered for using a mid-infrared array camera in broad- and narrow-band solar imaging observations. The array camera system was designed for high-background 5–18 μm general astronomical imaging observations. The electronic and optical design of the camera, its photometric characteristics, examples of observational results, and the requirements for imaging in both high- and low-background solar applications are discussed.


Viruses ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1338
Author(s):  
Morgan E. Meissner ◽  
Emily J. Julik ◽  
Jonathan P. Badalamenti ◽  
William G. Arndt ◽  
Lauren J. Mills ◽  
...  

Human immunodeficiency virus type 2 (HIV-2) accumulates fewer mutations during replication than HIV type 1 (HIV-1). Advanced studies of HIV-2 mutagenesis, however, have historically been confounded by high background error rates in traditional next-generation sequencing techniques. In this study, we describe the adaptation of the previously described maximum-depth sequencing (MDS) technique to studies of both HIV-1 and HIV-2 for the ultra-accurate characterization of viral mutagenesis. We also present the development of a user-friendly Galaxy workflow for the bioinformatic analyses of sequencing data generated using the MDS technique, designed to improve replicability and accessibility to molecular virologists. This adapted MDS technique and analysis pipeline were validated by comparisons with previously published analyses of the frequency and spectra of mutations in HIV-1 and HIV-2 and is readily expandable to studies of viral mutation across the genomes of both viruses. Using this novel sequencing pipeline, we observed that the background error rate was reduced 100-fold over standard Illumina error rates, and 10-fold over traditional unique molecular identifier (UMI)-based sequencing. This technical advancement will allow for the exploration of novel and previously unrecognized sources of viral mutagenesis in both HIV-1 and HIV-2, which will expand our understanding of retroviral diversity and evolution.


2008 ◽  
Vol 310 (7-9) ◽  
pp. 2015-2019 ◽  
Author(s):  
P. Amedzake ◽  
E. Brown ◽  
U. Hömmerich ◽  
S.B. Trivedi ◽  
J.M. Zavada

Nanophotonics ◽  
2014 ◽  
Vol 3 (4-5) ◽  
pp. 329-341 ◽  
Author(s):  
Raji Shankar ◽  
Marko Lončar

AbstractThe mid-infrared (IR) wavelength region (2–20 µm) is of great interest for a number of applications, including trace gas sensing, thermal imaging, and free-space communications. Recently, there has been significant progress in developing a mid-IR photonics platform in Si, which is highly transparent in the mid-IR, due to the ease of fabrication and CMOS compatibility provided by the Si platform. Here, we discuss our group’s recent contributions to the field of silicon-based mid-IR photonics, including photonic crystal cavities in a Si membrane platform and grating-coupled high-quality factor ring resonators in a silicon-on-sapphire (SOS) platform. Since experimental characterization of microphotonic devices is especially challenging at the mid-IR, we also review our mid-IR characterization techniques in some detail. Additionally, pre- and post-processing techniques for improving device performance, such as resist reflow, Piranha clean/HF dip cycling, and annealing are discussed.


2017 ◽  
Vol 601 ◽  
pp. A65 ◽  
Author(s):  
Sebastian Daemgen ◽  
Kamen Todorov ◽  
Jasmin Silva ◽  
Derek Hand ◽  
Eugenio V. Garcia ◽  
...  
Keyword(s):  

2018 ◽  
Vol 440 ◽  
pp. 939-945 ◽  
Author(s):  
Bo Wen Jia ◽  
Kian Hua Tan ◽  
Wan Khai Loke ◽  
Satrio Wicaksono ◽  
Soon Fatt Yoon
Keyword(s):  

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