Three dimensional time reversal optical tomography

Author(s):  
Binlin Wu ◽  
W. Cai ◽  
M. Alrubaiee ◽  
M. Xu ◽  
S. K. Gayen
Sensors ◽  
2021 ◽  
Vol 21 (11) ◽  
pp. 3652
Author(s):  
Cory Juntunen ◽  
Isabel M. Woller ◽  
Yongjin Sung

Hyperspectral three-dimensional (3D) imaging can provide both 3D structural and functional information of a specimen. The imaging throughput is typically very low due to the requirement of scanning mechanisms for different depths and wavelengths. Here we demonstrate hyperspectral 3D imaging using Snapshot projection optical tomography (SPOT) and Fourier-transform spectroscopy (FTS). SPOT allows us to instantaneously acquire the projection images corresponding to different viewing angles, while FTS allows us to perform hyperspectral imaging at high spectral resolution. Using fluorescent beads and sunflower pollens, we demonstrate the imaging performance of the developed system.


2021 ◽  
Vol 11 (4) ◽  
pp. 1670
Author(s):  
Tetsuya Mimura ◽  
Shinpei Okawa ◽  
Hiroshi Kawaguchi ◽  
Yukari Tanikawa ◽  
Yoko Hoshi

Thyroid cancer is usually diagnosed by ultrasound imaging and fine-needle aspiration biopsy. However, diagnosis of follicular thyroid carcinomas (FTC) is difficult because FTC lacks nuclear atypia and a consensus on histological interpretation. Diffuse optical tomography (DOT) offers the potential to diagnose FTC because it can measure tumor hypoxia, while image reconstruction of the thyroid is still challenging mainly due to the complex anatomical features of the neck. In this study, we attempted to solve this issue by creating a finite element model of the human neck excluding the trachea (a void region). By reconstruction of the absorption coefficients at three wavelengths, 3D tissue oxygen saturation maps of the human thyroid are obtained for the first time by DOT.


2012 ◽  
Vol 17 (12) ◽  
pp. 126009 ◽  
Author(s):  
Kirstin Baum ◽  
Raimo Hartmann ◽  
Tobias Bischoff ◽  
Jan O. Oelerich ◽  
Stephan Finkensieper ◽  
...  

2014 ◽  
Vol 22 (3) ◽  
Author(s):  
Caifang Wang

Abstract.Diffuse optical tomography (DOT) is an optical imaging modality, which provides the spatial distribution of the optical parameters inside a random medium. A propagation back-propagation method named EM-like reconstruction method for stationary DOT problem has been proposed yet. This method is really time consuming. Hence the ordered-subsets (OS) technique for this reconstruction method is studied in this paper. The boundary measurements of DOT are grouped into nonoverlapping and overlapping ordered sequence of subsets with random partition, sequential partition and periodic partition, respectively. The performance of OS methods is compared with the standard EM-like reconstruction method with two-dimensional and three-dimensional numerical experiments. The numerical experiments indicate that reconstruction of nonoverlapping subsets with periodic partition, overlapping subsets with periodic partition and standard EM-like method provide very similar acceptable reconstruction results. However, reconstruction of nonoverlapping subsets with periodic partition spends a minimum of time to get proper results.


2008 ◽  
Vol 27 (6) ◽  
pp. 752-765 ◽  
Author(s):  
G. Boverman ◽  
E.L. Miller ◽  
D.H. Brooks ◽  
D. Isaacson ◽  
Qianqian Fang ◽  
...  

2011 ◽  
Vol 97 (5) ◽  
pp. 728-733
Author(s):  
Yang Liu ◽  
Xiasheng Guo ◽  
Zhao Da ◽  
Dong Zhang ◽  
Xiufen Gong

This article proposes an acoustic nonlinear approach combined with the time reversal technique to image cracks in long bones. In this method, the scattered ultrasound generated from the crack is recorded, and the third harmonic nonlinear component of the ultrasonic signal is used to reconstruct an image of the crack by the time reversal process. Numerical simulations are performed to examine the validity of this approach. The fatigue long bone is modeled as a hollow cylinder with a crack of 1, 0.1, and 0.225 mm in axial, radial and circumferential directions respectively. A broadband 500 kHz ultrasonic signal is used as the exciting signal, and the extended three-dimensional Preisach-Mayergoyz model is used to describe the nonclassical nonlinear dynamics of the crack. Time reversal is carried out by using the filtered third harmonic component. The localization capability depends on the radial depth of the crack.


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