WE-G-204-05: Relative Object Detectability Evaluation of a New High Resolution A-Se Direct Detection System Compared to Indirect Micro-Angiographic Fluoroscopic (MAF) Detectors

2015 ◽  
Vol 42 (6Part40) ◽  
pp. 3694-3695 ◽  
Author(s):  
M Russ ◽  
S Setlur Nagesh ◽  
C Ionita ◽  
C Scott ◽  
K Karim ◽  
...  
Keyword(s):  
High Resolution ◽  
Direct Detection ◽  
Detection System

Direct Detection System forEscherichia coliUsing Au–Ag Alloy Microchips

2013 ◽  
Vol 52 (22) ◽  
pp. 7282-7288 ◽  
Author(s):  
Wan-Joong Kim ◽  
Sanghee Kim ◽  
Ae Rhan Kim ◽  
Dong Jin Yoo
Keyword(s):  
Direct Detection ◽  
Detection System

scholarly journals GEM-Based Detectors for Direct Detection of Low-Mass WIMP, Solar Axions and Narrow Resonances (Quarks)

2021 ◽  
Author(s):  
Victor Parusov ◽  
Boris Ovchinnikov
Keyword(s):  
Direct Detection ◽  
Detection System ◽  
Beta Particle ◽  
Gaseous Mixtures ◽  
Low Mass ◽  
Nonzero Spin ◽  
Time Projection ◽  
First Time ◽  
Solar Axions ◽  
Low Mass Wimp

Gas electron multipliers (GEMs) with wire (WGEMs) or metal electrodes (MGEMs), which don’t use any plastic insulators between electrodes are created. The chambers containing MGEMs (WGEMs) with pin-anodes are proposed as detectors for searching of spin-dependent interactions between Dark Matter (DM) particles and gases with nonzero-spin nuclei (H2, D2, 3He, 21Ne, CF4, CH4, etc.). In this paper, we present a review of such chambers. For investigation of the gas mixtures Ne+10%H2, H2 (D2) +3ppmTMAE, the chamber containing WGEM with pin-anode detection system was constructed. In this paper we present the results of an experimental study of these gaseous mixtures exited by an α - source. Mixture of Ar + 40 ppm C2H4 and mixture 50% Xe + 50%CF4 have been investigated. The spatial distributions of photoelectron clouds produced by primary scintillations on α- and β-particle tracks, as well as the distributions of photoelectron clouds due to photons from avalanches at the pin-anode, have been measured for the first time. In our experiments as another filling of the chambers for search of low-mas WIMP (<10 GeV/c2), solar neutrino and solar axions with spin-dependent interaction we propose to use the mixtures: D2 + 3ppmTMAE, 3He + 3%CH4, 21Ne + 10%H2, at pressure 10-17 bar. And in our experiment with liquid gases is used the mixtures with 19F (LAr + CF4, LXe + CF4) and mixture LCH4 + 40ppm TMAE. The time projection chamber (TPC) with the mixture D2 + 3ppmTMAE filling allow to search of spin-dependent interactions of solar axions and deuterium. As well as we present the detecting systems for search of narrow pp-resonances (quarks) in accelerators experiments.

scholarly journals An Optimized In-column Detection System for the Ultra-high Resolution BrightBeamTM SEM Column

2020 ◽  
Vol 26 (S2) ◽  
pp. 1806-1807
Author(s):  
Jaroslav Jiruše ◽  
Petr Sytař ◽  
Jan Páral ◽  
Tomáš Hrnčíř
Keyword(s):  
High Resolution ◽  
Detection System

High Resolution Screening of Plant Natural Product Extracts for Estrogen Receptor α and β Binding Activity Using an Online HPLC-MS Biochemical Detection System

2001 ◽  
Vol 6 (5) ◽  
pp. 291-303 ◽  
Author(s):  
Uwe Schobel ◽  
Michel Frenay ◽  
Danny A. van Elswijk ◽  
Joanne M. McAndrews ◽  
Kelly R. Long ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
High Resolution ◽  
Natural Product ◽  
Detection System ◽  
Estrogen Receptor Α ◽  
Binding Activity ◽  
Biochemical Detection

Progress with the IBM Very High Resolution STEM

2001 ◽  
Vol 7 (S2) ◽  
pp. 234-235
Author(s):  
RE. Batson ◽  
H.W. Mook ◽  
P. Kruit ◽  
O.L. Krivanek ◽  
N. Dellby
Keyword(s):  
High Resolution ◽  
Detection System ◽  
Spherical Aberration ◽  
Electron Gun ◽  
Fringe Field ◽  
Recent Effort ◽  
Electron Monochromator ◽  
Set Up ◽  
Main Activity ◽  
Many Sources

The IBM high resolution STEM project has now reached the point where integration of new subsystems into the instrument is the main activity. During the past three years, we have demonstrated a 50meV EELS resolution using a high brightness electron monochromator incorporated into the electron gun [1, 2, 3], and better than 0.14mn spatial resolution using spherical aberration correction at 120KeV. [4] Recent effort has been to identify and remove many sources of instabilities in the original instrument; to rebuild several existing subsidiary pieces of equipment such as the ADF detector, the EELS spectrometer electron optical coupling, and the EELS CCD detection system; and to set up software and hardware control of each system to allow routine operation.The new STEM column is summarized in Fig. 1. Briefly, the original VG gun flange has been lowered about 4cm, using a spacer, to allow insertion of the Fringe Field monochromator.

scholarly journals Direct Detection of Rifampin and Isoniazid Resistance in Sputum Samples from Tuberculosis Patients by High-Resolution Melt Curve Analysis

2017 ◽  
Vol 55 (6) ◽  
pp. 1755-1766 ◽  
Author(s):  
Divya Anthwal ◽  
Rakesh Kumar Gupta ◽  
Manpreet Bhalla ◽  
Shinjini Bhatnagar ◽  
Jaya Sivaswami Tyagi ◽  
...  
Keyword(s):  
High Resolution ◽  
Direct Detection ◽  
Melting Curve ◽  
Curve Analysis ◽  
High Resolution Melt ◽  
Melt Curve Analysis ◽  
Content Type ◽  
Plasmid Library ◽  
Mdr Tb ◽  
Smear Negative

ABSTRACT Drug-resistant tuberculosis (TB) is a major threat to TB control worldwide. Globally, only 40% of the 340,000 notified TB patients estimated to have multidrug-resistant-TB (MDR-TB) were detected in 2015. This study was carried out to evaluate the utility of high-resolution melt curve analysis (HRM) for the rapid and direct detection of MDR-TB in Mycobacterium tuberculosis in sputum samples. A reference plasmid library was first generated of the most frequently observed mutations in the resistance-determining regions of rpoB , katG , and an inhA promoter and used as positive controls in HRM. The assay was first validated in 25 MDR M. tuberculosis clinical isolates. The assay was evaluated on DNA isolated from 99 M. tuberculosis culture-positive sputum samples that included 84 smear-negative sputum samples, using DNA sequencing as gold standard. Mutants were discriminated from the wild type by comparing melting-curve patterns with those of control plasmids using HRM software. Rifampin (RIF) and isoniazid (INH) monoresistance were detected in 11 and 21 specimens, respectively, by HRM. Six samples were classified as MDR-TB by sequencing, one of which was missed by HRM. The HRM-RIF, INH- katG , and INH- inhA assays had 89% (95% confidence interval [CI], 52, 100%), 85% (95% CI, 62, 97%), and 100% (95% CI, 74, 100%) sensitivity, respectively, in smear-negative samples, while all assays had 100% sensitivity in smear-positive samples. All assays had 100% specificity. Concordance of 97% to 100% (κ value, 0.9 to 1) was noted between sequencing and HRM. Heteroresistance was observed in 5 of 99 samples by sequencing. In conclusion, the HRM assay was a cost-effective (Indian rupee [INR]400/US$6), rapid, and closed-tube method for the direct detection of MDR-TB in sputum, especially for direct smear-negative cases.

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