Comparison of attenuation compensation methods in the estimation of the backscatter coefficient of breast cancer

2021 ◽  
Vol 150 (4) ◽  
pp. A55-A55
Author(s):  
Laura Castañeda-Martinez ◽  
Hayley Whitson ◽  
Noushin Jafarpisheh ◽  
Jorge Castillo-Lopez ◽  
Hector Galvan-Espinosa ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Backscatter Coefficient ◽  
Attenuation Compensation ◽  
Compensation Methods

Quantification of the backscatter coefficient in heterogeneous media: Comparison of attenuation compensation methods

2020 ◽  
Vol 148 (4) ◽  
pp. 2559-2559
Author(s):  
Laura Casta ñeda-Martinez ◽  
Timothy J. Hall ◽  
Noushin Jafarpisheh ◽  
Hayley Whitson ◽  
Hassan Rivaz ◽  
...  
Keyword(s):  
Heterogeneous Media ◽  
Backscatter Coefficient ◽  
Attenuation Compensation ◽  
Media Comparison ◽  
Compensation Methods

scholarly journals Multiparametric ultrasound examination for response assessment in breast cancer patients undergoing neoadjuvant therapy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
K. Dobruch-Sobczak ◽  
H. Piotrzkowska-Wróblewska ◽  
Z. Klimonda ◽  
P. Karwat ◽  
K. Roszkowska-Purska ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Characteristic Curve ◽  
Poor Response ◽  
Maximum Diameter ◽  
Breast Cancer Patients ◽  
Backscatter Coefficient ◽  
Linear Discriminant ◽  
The Third ◽  
Multiparametric Ultrasound

AbstractTo investigate the performance of multiparametric ultrasound for the evaluation of treatment response in breast cancer patients undergoing neoadjuvant chemotherapy (NAC). The IRB approved this prospective study. Breast cancer patients who were scheduled to undergo NAC were invited to participate in this study. Changes in tumour echogenicity, stiffness, maximum diameter, vascularity and integrated backscatter coefficient (IBC) were assessed prior to treatment and 7 days after four consecutive NAC cycles. Residual malignant cell (RMC) measurement at surgery was considered as standard of reference. RMC < 30% was considered a good response and > 70% a poor response. The correlation coefficients of these parameters were compared with RMC from post-operative histology. Linear Discriminant Analysis (LDA), cross-validation and Receiver Operating Characteristic curve (ROC) analysis were performed. Thirty patients (mean age 56.4 year) with 42 lesions were included. There was a significant correlation between RMC and echogenicity and tumour diameter after the 3rd course of NAC and average stiffness after the 2nd course. The correlation coefficient for IBC and echogenicity calculated after the first four doses of NAC were 0.27, 0.35, 0.41 and 0.30, respectively. Multivariate analysis of the echogenicity and stiffness after the third NAC revealed a sensitivity of 82%, specificity of 90%, PPV = 75%, NPV = 93%, accuracy = 88% and AUC of 0.88 for non-responding tumours (RMC > 70%). High tumour stiffness and persistent hypoechogenicity after the third NAC course allowed to accurately predict a group of non-responding tumours. A correlation between echogenicity and IBC was demonstrated as well.

Total attenuation compensation for backscatter coefficient estimation using full angular spatial compounding

Ultrasonics ◽  
2021 ◽  
Vol 114 ◽  
pp. 106376
Author(s):  
Andres Coila ◽  
Julien Rouyer ◽  
Omar Zenteno ◽  
Adam Luchies ◽  
Michael L. Oelze ◽  
...  
Keyword(s):  
Backscatter Coefficient ◽  
Spatial Compounding ◽  
Total Attenuation ◽  
Attenuation Compensation ◽  
Coefficient Estimation

Virus-Like Particles in a Human Breast Cancer: Structural Similarity to Previously Reported Particles

1973 ◽  
Vol 31 ◽  
pp. 378-379
Author(s):  
G. Kasnic ◽  
S. E. Stewart ◽  
C. Urbanski
Keyword(s):  
Breast Cancer ◽  
Biological Activity ◽  
Human Breast Cancer ◽  
Osteogenic Sarcoma ◽  
Human Tumor ◽  
Structural Similarity ◽  
Cell Tumor ◽  
Human Breast ◽  
Human Tumor Cell ◽  
Type Particle

We have reported the maturation of an intracisternal A-type particle in murine plasma cell tumor cultures and three human tumor cell cultures (rhabdomyosarcoma, lung adenocarcinoma, and osteogenic sarcoma) after IUDR-DMSO activation. In all of these studies the A-type particle seems to develop into a form with an electron dense nucleoid, presumably mature, which is also intracisternal. A similar intracisternal A-type particle has been described in leukemic guinea pigs. Although no biological activity has yet been demonstrated for these particles, on morphologic grounds, and by the manner in which they develop within the cell, they may represent members of the same family of viruses.

Further Ultrastructural Observations on Metastatic Nodules of Human Breast Cancer

1968 ◽  
Vol 26 ◽  
pp. 224-225
Author(s):  
John L. Swedo ◽  
R. W. Talley ◽  
John H. L. Watson
Keyword(s):  
Breast Cancer ◽  
Human Breast Cancer ◽  
Estrogen Therapy ◽  
Specimen Preparation ◽  
Human Breast ◽  
Autophagic Vacuoles ◽  
Previous Communication ◽  
Linear Profiles ◽  
Metastatic Nodule

Since the report, which described the ultrastructure of a metastatic nodule of human breast cancer after estrogen therapy, additional ultrastructural observations, including some which are correlative with pertinent findings in the literature concerning mycoplasmas, have been recorded concerning the same subject. Specimen preparation was identical to that in.The mitochondria possessed few cristae, and were deteriorated and vacuolated. They often contained particulates and fibrous structures, sometimes arranged in spindle-shaped bundles, Fig. 1. Another apparent aberration was the occurrence, Fig. 2 (arrows) of linear profiles of what seems to be SER, which lie between layers of RER, and are often recognizably continuous with them.It was noted that the structure of the round bodies, interpreted as within autophagic vacuoles in the previous communication, and of vesicular bodies, described morphologically closely resembled those of some mycoplasmas. Specifically, they simulated or reflected the various stages of replication reported for mycoplasmas grown on solid nutrient. Based on this observation, they are referred to here as “mycoplasma-like” structures, in anticipation of confirmatory evidence from investigations now in progress.

The proliferation of breast cancer cells are inhibited by the human intrabody targeting cyclinD1

2010 ◽  
Vol 34 (8) ◽  
pp. S49-S49
Author(s):  
Lei Wang ◽  
Xun Zhou ◽  
Lihong Zhou ◽  
Yong Chen ◽  
Xun Zhu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells

Study of the mechanism responsible for multidrug resistance in breast cancer MCF-7 cell mediated by 14-3-3σ

2010 ◽  
Vol 34 (8) ◽  
pp. S47-S47
Author(s):  
Guopei Zheng ◽  
Sisi Yi ◽  
Yafei Li ◽  
Fangren Kong ◽  
Yanhui Yu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Multidrug Resistance ◽  
Mcf 7
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