Allometric Scaling Factors for Oxygen Uptake during Exercise in Children

1995 ◽  
Vol 7 (1) ◽  
pp. 12-25 ◽  
Author(s):  
Danette M. Rogers ◽  
Kenneth R. Turley ◽  
Kathleen I. Kujawa ◽  
Kevin M. Harper ◽  
Jack H. Wilmore

This study was designed to examine the relationship between oxygen consumption and both body surface area and body mass in children to determine what allometric scaling factors from these variables provide appropriate means of expressing data for this population. These scaling factors were then compared to exponents based on theoretical and animal models to determine if the same relationships were present. Forty-two children (21 boys and 21 girls) 7 to 9 years of age participated in maximal and submaximal treadmill testing. The submaximal V̇O2 to body size relationship proved to be a more appropriate factor to use when scaling V̇O2 than the relationship seen between body size and V̇O2max. Therefore, in this population of children, V̇O2 relative to body surface area or body mass to the power 0.67, demonstrated submaximally, provided a more appropriate means of data expression both statistically and physiologically than the traditional expression of V̇O2 relative to body mass (ml·kg−1·min−1).

Author(s):  
Shirazu I. ◽  
Theophilus. A. Sackey ◽  
Elvis K. Tiburu ◽  
Mensah Y. B. ◽  
Forson A.

The relationship between body height and body weight has been described by using various terms. Notable among them is the body mass index, body surface area, body shape index and body surface index. In clinical setting the first descriptive parameter is the BMI scale, which provides information about whether an individual body weight is proportionate to the body height. Since the development of BMI, two other body parameters have been developed in an attempt to determine the relationship between body height and weight. These are the body surface area (BSA) and body surface index (BSI). Generally, these body parameters are described as clinical health indicators that described how healthy an individual body response to the other internal organs. The aim of the study is to discuss the use of BSI as a better clinical health indicator for preclinical assessment of body-organ/tissue relationship. Hence organ health condition as against other body composition. In addition the study is `also to determine the best body parameter the best predict other parameters for clinical application. The model parameters are presented as; modeled height and weight; modelled BSI and BSA, BSI and BMI and modeled BSA and BMI. The models are presented as clinical application software for comfortable working process and designed as GUI and CAD for use in clinical application.


2012 ◽  
Vol 44 (2) ◽  
pp. 203-210 ◽  
Author(s):  
Sina Alipour ◽  
Hagen F. Kennecke ◽  
Ryan Woods ◽  
Howard J. Lim ◽  
Caroline Speers ◽  
...  

2019 ◽  
pp. 196-197
Author(s):  
Natalia Kirsten

Objective: Psoriasis and depression may have common mechanisms, such as systemic inflammation, dysfunction of the hypothalamic-pituitary-adrenal axis, and vitamin D3 deficiency. Among men with psoriasis, this study examined whether depression severity was associated with serum concentrations of different metabolic and inflammatory markers.Methods: The study included 85 men with psoriasis (mean age ±standard deviation [SD], 47 ±14 years) and 65 men without psoriasis (mean age ±SD, 44 ±13 years). In both groups, we measured the body mass index; blood pressure; and serum concentrations of lipids, uric acid, lipase, interleukins 6 and 18, cortisol, and 25-hydroxyvitamin D3. All participants completed the Beck Depression Inventory. Other variables analyzed included psoriasis duration, the Psoriasis Area Severity Index, and the percentage of body surface area affected by psoriatic lesions.Results: Compared with controls, patients with psoriasis had significantly greater depression severity, higher body mass indices, and higher serum concentrations of total cholesterol and interleukins 6 and 18; moreover, they had significantly lower serum 25-hydroxyvitamin D3 concentrations. In patients with psoriasis, depression severity correlated positively with psoriasis duration, the Psoriasis Area Severity Index, the percentage of body surface area affected by psoriatic lesions, and interleukin-18 concentration. In patients with psoriasis, depression severity correlated negatively with 25-hydroxyvitamin D3 concentration, but it did not correlate significantly with the serum concentrations of interleukin 6 and cortisol. Conclusion: High concentrations of interleukin 18 and low concentrations of 25-hydroxyvitamin D3 may be associated with depression severity in men with psoriasis. Thus, further studies should examine whether effective anti-inflammatory treatments or vitamin D3 supplementation can improve depression outcomes in these patients.


2017 ◽  
Vol 5 ◽  
Author(s):  
Karen Karimi ◽  
Iris Faraklas ◽  
Giavonni Lewis ◽  
Daniel Ha ◽  
Bridget Walker ◽  
...  

Abstract Background There is increasing evidence that sex differences may influence responses after thermal injury and affect clinical outcomes. The objective of this study was to evaluate the relationships between sex, thermal injury, body size, and inpatient mortality in burn patients. Methods Medical records of adults with >20% total body surface area (TBSA) burn injury admitted to two American Burn Association (ABA)-verified burn centers between 2008 and 2014 were retrospectively reviewed. Injury details and baseline characteristics, including body size as estimated by body surface area (BSA) and body mass index (BMI) were recorded, along with details of the hospital course. The primary outcome of inpatient mortality was compared between sexes. Results Out of 334 subjects, 60 were women (18%). Median TBSA was 33% (IQR 25–49) in this cohort, with 19% full thickness burns and 30% inhalation injury. Despite no significant difference in age, presence of inhalation injury, TBSA, or depth of burn, women had significantly higher rates of inpatient mortality (45 vs. 29%, P = 0.01). BSA was significantly lower in women vs. men (P < 0.001), but this difference was not more pronounced among non-survivors. There was no difference in BMI between men and women non-survivors. Although not significant (P = 0.28), women succumbed to their injuries sooner than men (day 4 vs. 10 post-injury). Conclusions Women are less likely to survive burn injuries and die sooner than men with similar injuries. Body size does not appear to modulate this effect. Burn centers should be aware of the higher mortality risk in women with large burns.


2013 ◽  
Vol 38 (5) ◽  
pp. e210-e215 ◽  
Author(s):  
Hongwei Si ◽  
Zhili Lei ◽  
Sijin Li ◽  
Jianzhong Liu ◽  
Jianhua Geng ◽  
...  

2016 ◽  
Vol 62 (1) ◽  
pp. 311-319 ◽  
Author(s):  
A. G. Hirst ◽  
M. K. S. Lilley ◽  
D. S. Glazier ◽  
D. Atkinson

2012 ◽  
Vol 23 (2) ◽  
pp. 113-117 ◽  
Author(s):  
Sion K. Roy ◽  
Irfan Zeb ◽  
Jigar Kadakia ◽  
Dong Li ◽  
Matthew J. Budoff

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