Pharmacokinetic Modeling of the Subcutaneous Absorption of Therapeutic Proteins

Drug Metabolism and Disposition ◽

10.1124/dmd.114.059121 ◽

2014 ◽

Vol 42 (11) ◽

pp. 1890-1905 ◽

Author(s):

Leonid Kagan

Keyword(s):

Therapeutic Proteins ◽

Pharmacokinetic Modeling ◽

Subcutaneous Absorption

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Role of Lymphatic System in Subcutaneous Absorption of Therapeutic Proteins

Pharmaceutical Sciences Encyclopedia ◽

10.1002/9780470571224.pse541 ◽

2015 ◽

pp. 1-10

Author(s):

Jiunn H. Lin ◽

Weirong Wang

Keyword(s):

Lymphatic System ◽

Therapeutic Proteins ◽

Subcutaneous Absorption

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A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins

The AAPS Journal ◽

10.1208/s12248-015-9819-4 ◽

2015 ◽

Vol 18 (1) ◽

pp. 156-170 ◽

Author(s):

Katherine L. Gill ◽

Iain Gardner ◽

Linzhong Li ◽

Masoud Jamei

Keyword(s):

Tissue Distribution ◽

Pharmacokinetic Model ◽

Therapeutic Proteins ◽

Physiologically Based Pharmacokinetic Model ◽

Bottom Up ◽

Physiologically Based Pharmacokinetic ◽

Subcutaneous Absorption ◽

Physiologically Based

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Interspecies Pharmacokinetic Modeling of Subcutaneous Absorption of Rituximab in Mice and Rats

Pharmaceutical Research ◽

10.1007/s11095-014-1416-1 ◽

2014 ◽

Vol 31 (12) ◽

pp. 3265-3273 ◽

Author(s):

Leonid Kagan ◽

Jie Zhao ◽

Donald E. Mager

Keyword(s):

Pharmacokinetic Modeling ◽

Subcutaneous Absorption

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Physiologically Based Pharmacokinetic Modeling of Therapeutic Proteins

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2017.03.038 ◽

2017 ◽

Vol 106 (9) ◽

pp. 2270-2275 ◽

Author(s):

Harvey Wong ◽

Timothy W. Chow

Keyword(s):

Therapeutic Proteins ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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439. Lifetime Exposures to Tetrachloroethylene Metabolites in Cancer Bioassays and in Exposed Human Populations, as Predicted By Pharmacokinetic Modeling

10.3320/1.2763307 ◽

1999 ◽

Author(s):

M. Holliday ◽

J. Park

Keyword(s):

Pharmacokinetic Modeling ◽

Human Populations

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Physiologically-based pharmacokinetic modeling of different size polyethylene glycol-coated gold nanoparticles in mice

10.1615/ihtc16.nmt.023362 ◽

2018 ◽

Author(s):

Linjing Deng ◽

Jinping Zhao ◽

Yufeng Miao ◽

Xu Hu ◽

Qihong Deng

Keyword(s):

Gold Nanoparticles ◽

Polyethylene Glycol ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Pharmacokinetic Modeling of Minocycline in a Murine Pneumonia Model

10.26226/morressier.57d6b2bfd462b8028d88ed0e ◽

2016 ◽

Author(s):

Jian Zhou

Keyword(s):

Pharmacokinetic Modeling

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Physiologically-Based Pharmacokinetic Modeling to Predict Changes in Drug Exposure during Pregnancy Using the Simcyp Simulator

10.26226/morressier.57d6b2b7d462b8028d88e945 ◽

2016 ◽

Author(s):

Suvarchala Kiranmai Avvari

Keyword(s):

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Exposure During Pregnancy

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Codon-optimized recombinant expression assay for a monomeric 17kDa basic fibroblast growth factor (bFGF) in transgenic alfalfa (Medicago sativa L.): blueprints towards human therapeutic proteins

Pakistan Journal of Botany ◽

10.30848/pjb2020-2(13) ◽

2019 ◽

Vol 52 (2) ◽

Author(s):

Liu Xiuming ◽

Naveed Ahmed ◽

Zhang Jiwei ◽

Wang Zhenghao ◽

Guo Yingnan ◽

...

Keyword(s):

Growth Factor ◽

Medicago Sativa ◽

Fibroblast Growth Factor ◽

Basic Fibroblast Growth Factor ◽

Recombinant Expression ◽

Therapeutic Proteins ◽

Fibroblast Growth ◽

Transgenic Alfalfa ◽

Medicago Sativa L

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Faculty Opinions recommendation of Managing uncertainty: a perspective on risk pertaining to product quality attributes as they bear on immunogenicity of therapeutic proteins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.736821421.793566705 ◽

2019 ◽

Author(s):

David Hayes

Keyword(s):

Product Quality ◽

Therapeutic Proteins ◽

Quality Attributes

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