A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.119.259846 ◽

2019 ◽

Vol 371 (2) ◽

pp. 290-298 ◽

Author(s):

Shuichi Takagahara ◽

Hiromi Shinohara ◽

Shigekazu Itokawa ◽

Yoshinori Satomi ◽

Ayumi Ando ◽

...

Keyword(s):

Fatty Acid Composition ◽

Acid Composition ◽

Knockout Mice ◽

Atherosclerotic Lesions ◽

Eicosanoid Production ◽

Apoe Knockout Mice ◽

Delta 5 Desaturase

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Faculty Opinions recommendation of A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.736562997.793566720 ◽

2019 ◽

Author(s):

John Imig

Keyword(s):

Fatty Acid Composition ◽

Acid Composition ◽

Knockout Mice ◽

Atherosclerotic Lesions ◽

Eicosanoid Production ◽

Apoe Knockout Mice ◽

Delta 5 Desaturase

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The effect of a fish oil diet on the fatty acid composition of individual phospholipids and eicosanoid production by rat platelets

Lipids ◽

10.1007/bf02535125 ◽

1989 ◽

Vol 24 (6) ◽

pp. 477-481 ◽

Author(s):

Mónica Careaga-Houck ◽

Howard Sprecher

Keyword(s):

Fatty Acid Composition ◽

Fish Oil ◽

Acid Composition ◽

Eicosanoid Production ◽

Fish Oil Diet ◽

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Effects of continuous tube feeding of dietary fat emulsions on eicosanoid production and on fatty acid composition during an acute septic shock in rats

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism ◽

10.1016/0005-2760(94)90081-7 ◽

1994 ◽

Vol 1214 (3) ◽

pp. 333-339 ◽

Author(s):

Tohru Utsunomiya ◽

Sambasiva R. Chavali ◽

W. William Zhong ◽

R.Armour Forse

Keyword(s):

Septic Shock ◽

Fatty Acid Composition ◽

Acid Composition ◽

Dietary Fat ◽

Tube Feeding ◽

Fat Emulsions ◽

Eicosanoid Production

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Dietary linoleic acid affects phospholipid fatty acid composition in heart and eicosanoid production by cardiomyocytes from atlantic salmon (Salmo salar)

Comparative Biochemistry and Physiology Part A Physiology ◽

10.1016/0300-9629(92)90591-d ◽

1992 ◽

Vol 103 (2) ◽

pp. 337-342 ◽

Author(s):

J.Gordon Bell ◽

James R Dick ◽

John R Sargent ◽

Alasdair H Mcvicar

Keyword(s):

Fatty Acid Composition ◽

Linoleic Acid ◽

Atlantic Salmon ◽

Acid Composition ◽

Salmo Salar ◽

Phospholipid Fatty Acid ◽

Phospholipid Fatty Acid Composition ◽

Dietary Linoleic Acid ◽

Eicosanoid Production

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Fatty acid composition, eicosanoid production and permeability in skin tissues of rainbow trout (Oncorhynchus mykiss) fed a control or an essential fatty acid deficient diet

Prostaglandins Leukotrienes and Essential Fatty Acids ◽

10.1016/s0952-3278(97)90603-7 ◽

1997 ◽

Vol 56 (6) ◽

pp. 479-489 ◽

Author(s):

C. Ghioni ◽

J.G. Bell ◽

M.V. Bell ◽

J.R. Sargent

Keyword(s):

Fatty Acid Composition ◽

Rainbow Trout ◽

Oncorhynchus Mykiss ◽

Essential Fatty Acid ◽

Acid Composition ◽

Deficient Diet ◽

Rainbow Trout Oncorhynchus Mykiss ◽

Eicosanoid Production ◽

Essential Fatty Acid Deficient

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Modification of membrane fatty acid composition, eicosanoid production, and phospholipase a activity in Atlantic Salmon (Salmo salar) gill and kidney by dietary lipid

Lipids ◽

10.1007/bf02524291 ◽

1996 ◽

Vol 31 (11) ◽

pp. 1163-1171 ◽

Author(s):

J. Gordon Bell ◽

Bruce M. Farndale ◽

James R. Dick ◽

John R. Sargent

Keyword(s):

Fatty Acid Composition ◽

Atlantic Salmon ◽

Acid Composition ◽

Salmo Salar ◽

Dietary Lipid ◽

Phospholipase A ◽

Membrane Fatty Acid ◽

Membrane Fatty Acid Composition ◽

Eicosanoid Production

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Effect of diets rich in linoleic or α-linolenic acid on phospholipid fatty acid composition and eicosanoid production in atlantic salmon (Salmo salar)

Lipids ◽

10.1007/bf02536236 ◽

1993 ◽

Vol 28 (9) ◽

pp. 819-826 ◽

Author(s):

J. Gordon Bell ◽

James R. Dick ◽

John R. Sargent

Keyword(s):

Fatty Acid Composition ◽

Atlantic Salmon ◽

Linolenic Acid ◽

Acid Composition ◽

Salmo Salar ◽

Phospholipid Fatty Acid ◽

Phospholipid Fatty Acid Composition ◽

Atlantic Salmon Salmo Salar ◽

Eicosanoid Production

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Effect of Dietary Linoleic, .ALPHA.-Linolenic and Arachidonic Acids on Lipid Metabolism, Tissue Fatty Acid Composition and Eicosanoid Production in Rats.

Journal of Nutritional Science and Vitaminology ◽

10.3177/jnsv.42.541 ◽

1996 ◽

Vol 42 (6) ◽

pp. 541-551 ◽

Author(s):

Ikuo IKEDA ◽

Kousuke MITSUI ◽

Katsumi IMAIZUMI

Keyword(s):

Fatty Acid Composition ◽

Lipid Metabolism ◽

Acid Composition ◽

Tissue Fatty Acid Composition ◽

Tissue Fatty Acid ◽

Eicosanoid Production ◽

Arachidonic Acids

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Interaction of Dietary Protein and Alpha-Linolenic Acid on Polyunsaturated Fatty Acid Composition of Liver Microsomal Phospholipids and Eicosanoid Production in Streptozotocin-lnduced Diabetic Rats

Annals of Nutrition and Metabolism ◽

10.1159/000177757 ◽

1993 ◽

Vol 37 (3) ◽

pp. 101-109 ◽

Author(s):

Akira Ikeda ◽

Michihiro Sugano

Keyword(s):

Fatty Acid Composition ◽

Linolenic Acid ◽

Acid Composition ◽

Polyunsaturated Fatty Acid ◽

Dietary Protein ◽

Diabetic Rats ◽

Alpha Linolenic Acid ◽

Eicosanoid Production

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Arachidonate and Docosahexaenoate Added to Infant Formula Influence Fatty Acid Composition and Subsequent Eicosanoid Production in Neonatal Pigs

Journal of Nutrition ◽

10.1093/jn/126.9.2199 ◽

1996 ◽

Vol 126 (9) ◽

pp. 2199-2208 ◽

Author(s):

Meng-Chuan Huang ◽

Margaret C. Craig-Schmidt

Keyword(s):

Fatty Acid Composition ◽

Infant Formula ◽

Acid Composition ◽

Neonatal Pigs ◽

Eicosanoid Production

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