scholarly journals Xanthines Down-Regulate the Drug Transporter ABCG2 and Reverse Multidrug Resistance

2011 ◽  
Vol 81 (3) ◽  
pp. 328-337 ◽  
Author(s):  
Rui Ding ◽  
Jia Shi ◽  
Kirk Pabon ◽  
Kathleen W. Scotto
Keyword(s):  
Multidrug Resistance ◽  
Drug Transporter

Therapeutic Potential of Endophytic Compounds: A Special Reference to Drug Transporter Inhibitors

2019 ◽  
Vol 19 (10) ◽  
pp. 754-783 ◽  
Author(s):  
Khusbu Singh ◽  
Gaurav Raj Dwivedi ◽  
A. Swaroop Sanket ◽  
Sanghamitra Pati
Keyword(s):  
Drug Resistance ◽  
Multidrug Resistance ◽  
Therapeutic Potential ◽  
Drug Transporters ◽  
Chemotherapeutic Agents ◽  
Chemical Diversity ◽  
Drug Transporter ◽  
Reversal Agents ◽  
Resistance Reversal ◽  
Novel Drug

From the discovery to the golden age of antibiotics (miracle), millions of lives have been saved. The era of negligence towards chemotherapeutic agents gave birth to drug resistance. Among all the regulators of drug resistance, drug transporters are considered to be the key regulators for multidrug resistance. These transporters are prevalent from prokaryotes to eukaryotes. Endophytes are one of the unexplored wealths of nature. Endophytes are a model mutualistic partner of plants. They are the reservoir of novel therapeutics. The present review deals with endophytes as novel drug resistance reversal agents by inhibiting the drug transporters across the genera. This review also focuses on drug transporters, and mutualistic chemical diversity, exploring drug transporter modulating potential of endophytes.

scholarly journals Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

2003 ◽  
Vol 348 (15) ◽  
pp. 1442-1448 ◽  
Author(s):  
Asra Siddiqui ◽  
Reinhold Kerb ◽  
Michael E. Weale ◽  
Ulrich Brinkmann ◽  
Alice Smith ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Drug Transporter

scholarly journals Drug-transporter proteins in clinical multidrug resistance

1992 ◽  
Vol 206 (1-2) ◽  
pp. 25-32 ◽  
Author(s):  
R.J. Scheper ◽  
H.J. Broxterman ◽  
G.L. Scheffer ◽  
C.J.L.M. Meijer ◽  
H.M. Pinedo
Keyword(s):  
Multidrug Resistance ◽  
Drug Transporter ◽  
Transporter Proteins

Metabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance

2005 ◽  
Vol 1 (2) ◽  
pp. 219-232 ◽  
Author(s):  
Nicole HP Cnubben ◽  
Heleen M Wortelboer ◽  
Jelmer J van Zanden ◽  
Ivonne MCM Rietjens ◽  
Peter J van Bladeren
Keyword(s):  
Multidrug Resistance ◽  
Atp Binding ◽  
Drug Transporter ◽  
Atp Binding Cassette
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