Molecular Virology:
            Early Interaction between Animal Viruses and Cells
            . Karl Lonberg-Holm and Lennart Philipson. Karger, Basel, 1974. x, 150 pp., illus. Paper, $35.75. Monographs in Virology, vol. 9.

: Enterovirus D68 (EV-D68) is a single-stranded positive-sense RNA virus, and it is one of the family Picornaviridae. Except for EV-D68, the family Picornaviridae has been illustrated in literature. EV-D68 was first discovered and isolated in California, USA, in 1962. EV-D68 has resulted in respiratory disorders’ outbreaks among children worldwide, and it has been detected in cases of various neurological diseases such as acute flaccid myelitis (AFM). A recent study documented a higher number of EV-D68 cases associated with AFM in Europe in 2016 compared to the 2014 outbreak. EV-D68 is mainly diagnosed by quantitative PCR, and there is an affirmative strategy for EV-D68 detection by using pan-EV PCR on the untranslated region and/or the VP1 or VP2, followed by sequencing of the PCR products. Serological tests are limited due to cross-reactivity of the antigens between the different serotypes. Many antiviral drugs for EV-D68 have been evaluated, and showed promising results. In our review, we discuss the current knowledge about EV-D68 and its role in the development of AFM.

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Event-related potentials suggest early interaction between syntax and semantics during on-line sentence comprehension

Neuroscience Letters ◽

10.1016/j.neulet.2005.04.076 ◽

2005 ◽

Vol 384 (3) ◽

pp. 222-227 ◽

Cited By ~ 34

Author(s):

Maria Palolahti ◽

Sakari Leino ◽

Markus Jokela ◽

Kreetta Kopra ◽

Petri Paavilainen

Keyword(s):

Sentence Comprehension ◽

Event Related Potentials ◽

Related Potentials ◽

On Line ◽

Early Interaction

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The acquisition of lexical tones by Cantonese–English bilingual children

Journal of Child Language ◽

10.1017/s0305000918000260 ◽

2018 ◽

Vol 45 (6) ◽

pp. 1357-1376 ◽

Cited By ~ 2

Author(s):

Peggy Pik Ki MOK ◽

Albert LEE

Keyword(s):

Stress Pattern ◽

Bilingual Children ◽

Phonological Development ◽

Lexical Tones ◽

English Bilingual ◽

Pitch Pattern ◽

Linguistic Transfer ◽

Auditory Analysis ◽

Early Interaction ◽

Time Point

AbstractPrevious studies on bilingual children found intact tonal development at the initial stages of interaction between Cantonese and English in successive bilingual children, whereas children exposed to both languages from birth have not been studied in this regard. We examined the production of Cantonese tones by five simultaneous bilingual children longitudinally at 2;0 and 2;6, and compared them with age-matched monolingual children using auditory analysis. Our results showed that some bilingual children had a delay at 2;0, compared to their monolingual peers. Some bilingual children also exhibited a ‘high–low’ template in their production, resembling the pitch pattern of English trochaic words. These findings suggest a possible early interaction of the Cantonese and English prosodic systems in which bilingual children adopted the English stress pattern in Cantonese production. The time-point along the trajectory of phonological development is important in modulating whether cross-linguistic transfer can be observed.

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Molecular virology by D. R. Harper. A medical perspectives book. Bios Scientific Publishers (1994). 154 pp. ISBN 1 872748 57 0

Reviews in Medical Virology ◽

10.1002/rmv.1980050307 ◽

1995 ◽

Vol 5 (3) ◽

pp. 181-181

Author(s):

Tim J. Harrison

Keyword(s):

Molecular Virology ◽

Scientific Publishers

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The Early Interaction of Coxsackievirus B3 with HeLa Cells

Experimental Biology and Medicine ◽

10.3181/00379727-137-35732 ◽

1971 ◽

Vol 137 (3) ◽

pp. 1082-1088 ◽

Cited By ~ 10

Author(s):

R. L. Crowell ◽

B. J. Landau ◽

L. Philipson

Keyword(s):

Hela Cells ◽

Coxsackievirus B3 ◽

Early Interaction

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How immunologic and genetic biomarkers impact Hodgkin lymphoma classification, diagnosis, and management: a huge potential that yet needs to be exploited

The International Journal of Biological Markers ◽

10.5301/ijbm.5000312 ◽

2017 ◽

Vol 33 (2) ◽

pp. 137-140 ◽

Cited By ~ 1

Author(s):

Antonino Carbone ◽

Annunziata Gloghini

Keyword(s):

Hodgkin Lymphoma ◽

Molecular Genetic ◽

Scientific Basis ◽

Grey Zone ◽

Molecular Virology ◽

Barr Virus ◽

Long Time ◽

Modern Classification ◽

Epstein Barr

“Ne è passata di acqua sotto i ponti.” It has been a long time since the diagnosis of Hodgkin lymphoma (HL) was exclusively based on the detection of typical Reed-Sternberg cells and the recognition of the characteristic morpho-histological background, as well as on the pathologist’s skill. The discovery of immunologic, molecular genetic and virologic biomarkers has provided an objective contribution to the diagnosis and a scientific basis for a modern classification of HL. Recent updates have clarified the nature of the so-called nodular lymphocyte predominant HL and its link to the T-cell/histiocyte-rich large B-cell lymphomas as well as its relationship with the lymphocyte-rich subset of classical HL (CHL). Molecular virology studies assessed a role for the Epstein-Barr virus in the pathogenesis of a fraction of CHL of the general population, and virtually in all cases of CHL occurring in people infected by HIV. Finally, immunologic and genetic findings corroborated the existence of grey zone lymphomas at the edges of CHL. Overall, these advances provided additional and useful information to address the treatment of patients affected by HL.

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