Entry of opioid peptides into the central nervous system

Science ◽  
1980 ◽  
Vol 207 (4426) ◽  
pp. 84-86 ◽  
Author(s):  
S. Rapoport ◽  
W. Klee ◽  
K. Pettigrew ◽  
K Ohno
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Opioid Peptides ◽  
The Central Nervous System

Transport of Opioid Peptides into the Central Nervous System

1998 ◽  
Vol 87 (11) ◽  
pp. 1433-1439 ◽  
Author(s):  
Richard D. Egleton ◽  
Thomas J. Abbruscato ◽  
Sarah A. Thomas ◽  
Thomas P. Davis
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Opioid Peptides ◽  
The Central Nervous System

Comparative distribution of three opioid peptides in the central nervous system of MacaccaFuscata

Pain ◽  
1987 ◽  
Vol 30 ◽  
pp. S245
Author(s):  
T. Ibuki ◽  
H. Okamura ◽  
M. Miyazaki ◽  
Y. Ibata
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Opioid Peptides ◽  
The Central Nervous System

scholarly journals Special Issue of International Journal of Molecular Sciences “Opioid Receptors and Endorphinergic Systems 2.0”

2021 ◽  
Vol 22 (16) ◽  
pp. 8365
Author(s):  
Carlo Ventura
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Opioid Receptors ◽  
Opioid Peptides ◽  
Neurotransmitter Release ◽  
Cellular Level ◽  
Receptor Subtypes ◽  
Special Issue ◽  
The Central Nervous System ◽  
And Control

Opioid peptides exhibit a wide-ranging tissue distribution and control multiple tissue functions not only through reflex mechanisms involving the central nervous system or the modulation of neurotransmitter release, but also by acting directly at the cellular level by targeting selected receptor subtypes (μ, δ, and κ are among the most frequently expressed) [...]

Effects of Hyperoxia on Lung Utrastructure

1970 ◽  
Vol 28 ◽  
pp. 26-27
Author(s):  
Gladys Harrison
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Light Microscopy ◽  
Oxygen Effects ◽  
Age Dependent ◽  
The Central Nervous System ◽  
The Subject ◽  
Space Age ◽  
Alveolar Septa ◽  
Extensive Damage

With the advent of the space age and the need to determine the requirements for a space cabin atmosphere, oxygen effects came into increased importance, even though these effects have been the subject of continuous research for many years. In fact, Priestly initiated oxygen research when in 1775 he published his results of isolating oxygen and described the effects of breathing it on himself and two mice, the only creatures to have had the “privilege” of breathing this “pure air”.Early studies had demonstrated the central nervous system effects at pressures above one atmosphere. Light microscopy revealed extensive damage to the lungs at one atmosphere. These changes which included perivascular and peribronchial edema, focal hemorrhage, rupture of the alveolar septa, and widespread edema, resulted in death of the animal in less than one week. The severity of the symptoms differed between species and was age dependent, with young animals being more resistant.

Emigration of neutrophils in the central nervous system

1983 ◽  
Vol 41 ◽  
pp. 788-789
Author(s):  
John L.Beggs ◽  
John D. Waggener ◽  
Wanda Miller ◽  
Jane Watkins
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Osmium Tetroxide ◽  
White Blood Cells ◽  
Arterial Perfusion ◽  
E Coli ◽  
Intracisternal Injection ◽  
The Central Nervous System ◽  
Brain And Spinal Cord ◽  
Interendothelial Junctions

Studies using mesenteric and ear chamber preparations have shown that interendothelial junctions provide the route for neutrophil emigration during inflammation. The term emigration refers to the passage of white blood cells across the endothelium from the vascular lumen. Although the precise pathway of transendo- thelial emigration in the central nervous system (CNS) has not been resolved, the presence of different physiological and morphological (tight junctions) properties of CNS endothelium may dictate alternate emigration pathways.To study neutrophil emigration in the CNS, we induced meningitis in guinea pigs by intracisternal injection of E. coli bacteria.In this model, leptomeningeal inflammation is well developed by 3 hr. After 3 1/2 hr, animals were sacrificed by arterial perfusion with 3% phosphate buffered glutaraldehyde. Tissues from brain and spinal cord were post-fixed in 1% osmium tetroxide, dehydrated in alcohols and propylene oxide, and embedded in Epon. Thin serial sections were cut with diamond knives and examined in a Philips 300 electron microscope.

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