Genetic Environment of 16S rRNA Methylase Gene rmtD

ABSTRACT The genetic environment of the 16S rRNA methylase gene rmtD was investigated. rmtD was flanked by a novel ISCR motif located downstream of class I integron In163 in the original Pseudomonas aeruginosa strain. rmtD found in Klebsiella pneumoniae appeared to have been mobilized from P. aeruginosa by an IS26-mediated event.

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Emergence of 16S rRNA methylase gene armA and cocarriage of blaIMP-1 in Pseudomonas aeruginosa isolates from South Korea

Diagnostic Microbiology and Infectious Disease ◽

10.1016/j.diagmicrobio.2010.07.021 ◽

2010 ◽

Vol 68 (4) ◽

pp. 468-470 ◽

Cited By ~ 23

Author(s):

Mamata Gurung ◽

Dong Chan Moon ◽

Migma Dorji Tamang ◽

Jungmin Kim ◽

Yoo Chul Lee ◽

...

Keyword(s):

Pseudomonas Aeruginosa ◽

16S Rrna ◽

South Korea ◽

Methylase Gene ◽

16S Rrna Methylase

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Draft Genome Sequence of a Sequence Type 11 Klebsiella pneumoniae Clinical Strain Carrying a blaKPC-2 Carbapenemase Gene and an rmtB 16S rRNA Methylase Gene

Genome Announcements ◽

10.1128/genomea.01549-16 ◽

2017 ◽

Vol 5 (6) ◽

Author(s):

Zhihong Yao ◽

Yu Feng ◽

Li Wei ◽

Zhiyong Zong

Keyword(s):

16S Rrna ◽

Klebsiella Pneumoniae ◽

Genome Sequence ◽

Draft Genome ◽

Draft Genome Sequence ◽

Clinical Strain ◽

Trna Genes ◽

Carbapenemase Gene ◽

Methylase Gene ◽

16S Rrna Methylase

ABSTRACT Klebsiella pneumoniae strain WCHKP649, recovered from a human wound, carried the carbapenemase gene bla KPC-2 and 16S rRNA methylase gene rmtB. Here, we report its 5.6-Mb draft genome sequence, comprising 171 contigs with an average 57.34% G+C content. The genome contained 5,284 coding sequences and 84 tRNA genes.

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Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa

The Lancet ◽

10.1016/s0140-6736(03)14959-8 ◽

2003 ◽

Vol 362 (9399) ◽

pp. 1888-1893 ◽

Cited By ~ 143

Author(s):

Keiko Yokoyama ◽

Yohei Doi ◽

Kunikazu Yamane ◽

Hiroshi Kurokawa ◽

Naohiro Shibata ◽

...

Keyword(s):

Pseudomonas Aeruginosa ◽

16S Rrna ◽

Methylase Gene ◽

16S Rrna Methylase

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Discrepant susceptibility to gentamicin despite amikacin resistance in Klebsiella pneumoniae by VITEK 2 represents false susceptibility associated with the armA 16S rRNA methylase gene

Journal of Medical Microbiology ◽

10.1099/jmm.0.000583 ◽

2017 ◽

Vol 66 (10) ◽

pp. 1448-1450 ◽

Cited By ~ 2

Author(s):

Jae-Hoon Ko ◽

Jin Yang Baek ◽

Kyong Ran Peck ◽

Sun Young Cho ◽

Young Eun Ha ◽

...

Keyword(s):

16S Rrna ◽

Klebsiella Pneumoniae ◽

Vitek 2 ◽

Methylase Gene ◽

16S Rrna Methylase

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In VitroActivity of Ceftazidime-Avibactam against 338 Molecularly Characterized Gentamicin-Nonsusceptible Gram-Negative Clinical Isolates Obtained from Patients in Canadian Hospitals

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.00364-15 ◽

2015 ◽

Vol 59 (6) ◽

pp. 3623-3626 ◽

Cited By ~ 6

Author(s):

Andrew J. Denisuik ◽

James A. Karlowsky ◽

Tyler Denisuik ◽

Wright W. Nichols ◽

Thomas A. Keating ◽

...

Keyword(s):

Pseudomonas Aeruginosa ◽

16S Rrna ◽

Klebsiella Pneumoniae ◽

Gram Negative Bacteria ◽

Aminoglycoside Resistance ◽

Single Strain ◽

Gram Negative ◽

Content Type ◽

16S Rrna Methylase

ABSTRACTThe mechanism of aminoglycoside resistance among 338 gentamicin-nonsusceptible Gram-negative bacteria (207Enterobacteriaceaeand 131Pseudomonas aeruginosa) was assessed, and thein vitroactivity of ceftazidime-avibactam against these isolates was determined. Aminoglycoside-modifying enzymes were detected in 91.8% ofEnterobacteriaceaeand 13.7% ofP. aeruginosaisolates. A single strain ofKlebsiella pneumoniaeharbored a 16S rRNA methylase (ArmA). The ceftazidime-avibactam MIC90values were 0.5 μg/ml (MIC, ≤8 μg/ml for 100% of isolates) and 16 μg/ml (MIC, ≤8 μg/ml for 87.8% of isolates) against gentamicin-nonsusceptibleEnterobacteriaceaeandP. aeruginosaisolates, respectively.

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