Lethal Action of Quinolones against a Temperature-Sensitive dnaB Replication Mutant of Escherichia coli
2006 ◽
Vol 50
(1)
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pp. 362-364
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Keyword(s):
ABSTRACT Inhibition of DNA replication in an Escherichia coli dnaB-22 mutant failed to block quinolone-mediated lethality. Inhibition of protein synthesis by chloramphenicol inhibited nalidixic acid lethality and, to a lesser extent, ciprofloxacin lethality in both dnaB-22 and wild-type cells. Thus, major features of quinolone-mediated lethality do not depend on ongoing replication.
1973 ◽
Vol 77
(1)
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pp. 99-108
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Keyword(s):
1977 ◽
Vol 99
(2)
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pp. 283-290
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1985 ◽
Vol 260
(9)
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pp. 5648-5653
Keyword(s):
1972 ◽
Vol 109
(2)
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pp. 945-948
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1977 ◽
Vol 115
(3)
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pp. 485-511
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1971 ◽
Vol 111
(2)
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pp. 145-158
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