Antibiotic Overproduction by rpsL and rsmG Mutants of Various Actinomycetes
2009 ◽
Vol 75
(14)
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pp. 4919-4922
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Keyword(s):
ABSTRACT Certain streptomycin resistance mutations (i.e., rpsL and rsmG) result in the overproduction of antibiotics in various actinomycetes. Moreover, rpsL rsmG double-mutant strains show a further increase in antibiotic production. rpsL but not rsmG mutations result in a marked enhancement of oligomycin production in Streptomyces avermitilis and erythromycin production in Saccharopolyspora erythraea, accompanied by increased transcription of a key developmental regulator gene, bldD, in the latter organism.
2009 ◽
Vol 20
(13)
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pp. 3055-3063
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Keyword(s):
2015 ◽
Vol 99
(23)
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pp. 10215-10224
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2008 ◽
Vol 74
(9)
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pp. 2834-2840
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1999 ◽
Vol 112
(16)
◽
pp. 2737-2751
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Keyword(s):
Keyword(s):
1980 ◽
Vol 22
(4)
◽
pp. 535-552
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Keyword(s):