scholarly journals Draft Genome Sequences of Helicobacter pylori Strains HPARG63 and HPARG8G, Cultured from Patients with Chronic Gastritis and Gastric Ulcer Disease

2013 ◽  
Vol 1 (5) ◽  
Author(s):  
R. I. Armitano ◽  
G. Zerbetto De Palma ◽  
M. J. Matteo ◽  
S. Revale ◽  
S. Romero ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastric Ulcer ◽  
Chronic Gastritis ◽  
Draft Genome ◽  
Genome Sequences ◽  
Ulcer Disease

scholarly journals Helicobacter Pylori Associated Antral Gastritis in Peptic Ulcer Disease Patients and Normal Healthy Population of Kashmir, India

1998 ◽  
Vol 4 (3) ◽  
pp. 135-139 ◽  
Author(s):  
Gh. Jeelani Romshoo ◽  
G. M. Malik ◽  
M. Youssuf Bhat ◽  
Ab. Rashid rather ◽  
Javaid Ahmad Basu ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Peptic Ulcer Disease ◽  
Healthy Volunteers ◽  
Chronic Gastritis ◽  
Healthy Population ◽  
Ulcer Disease ◽  
Antral Gastritis ◽  
H Pylori

Aim: To study the association of Helicobacter pylori infection with chronic antral gastritis in peptic ulcer disease patients and healthy population of Kashmir.Methods: 50 peptic ulcer patients (duodenal ulcer = 46, gastric ulcer = 2 and combined duodenal and gastric ulcer = 2) and 30 asymptomatic healthy volunteers were included in this study. Peptic ulcer was diagnosed on endoscopic examination. 4–6 punch biopsies were taken from gastric antrum in all the individuals and in case of gastric ulcer an additional biopsy was taken from the edge of the ulcer to exclude its malignant nature. Helicobacter pylori (H. pylori) organism was diagnosed using three different test methods, viz. Histology (using Giemsa Stain), Microbiology (Gram Stain) and Biochemistry (using one minute Endoscopy Room Test). Histological diagnosis of H. pylori was taken as the “gold standard” for the presence of H. pylori organism. Histological diagnosis of gastritis was made using Hematoxylin and Eosin Stain and the gastritis was classified as active chronic gastritis and superficial chronic gastritis.Results: Out of 30 peptic ulcer disease patients with associated antral gastritis, 27 (90%) were positive for H. pylori on histological examination (13 superficial chronic gastritis and 14 active chronic gastritis) whereas out of 8 healthy volunteers with histological evidence of chronic antral gastritis, H. pylori was observed in 7 individuals (87.50%) (4 active chronic gastritis and 3 superficial chronic gastritis).Conclusion: A highly significant association between H. pylori infection with chronic antral gastritis both in peptic ulcer disease patients and healthy volunteers of Kashmir was found in this study. Association between H. pylori infection and chronic gastritis was 90% in peptic ulcer group and 87.50% in healthy population (P<0.005).

scholarly journals Draft Genome Sequences of 29 Helicobacter pylori Strains Isolated from Colombia

2021 ◽  
Vol 10 (19) ◽  
Author(s):  
Angela B. Muñoz ◽  
Johanna Stepanian ◽  
Carmen Acosta ◽  
Juan S. Solano-Gutierrez ◽  
Filipa F. Vale ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Chronic Gastritis ◽  
Draft Genome ◽  
Genetic Composition ◽  
Genome Sequences ◽  
Content Type ◽  
Genomic Characterization ◽  
H Pylori

ABSTRACT Here, we present the draft genome sequences of 29 Colombian Helicobacter pylori strains. These strains were isolated in Bogotá, Colombia, from patients diagnosed with chronic gastritis. The genomic characterization of these strains will provide more information on the genetic composition of H. pylori strains from Colombia.

scholarly journals Association of IL1B -511C/-31T haplotype and Helicobacter pylori vacA genotypes with gastric ulcer and chronic gastritis

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Dinorah N Martínez-Carrillo ◽  
Elvira Garza-González ◽  
Reyes Betancourt-Linares ◽  
Trinidad Mónico-Manzano ◽  
Cuauhtémoc Antúnez-Rivera ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastric Ulcer ◽  
Chronic Gastritis

scholarly journals Anti-Helicobacter pylori and Anti-Inflammatory Effects and Constituent Analysis of Modified Xiaochaihutang for the Treatment of Chronic Gastritis and Gastric Ulcer

2018 ◽  
Vol 2018 ◽  
pp. 1-15 ◽  
Author(s):  
Xin Chen ◽  
Lijuan Hu ◽  
Huanhuan Wu ◽  
Wei Liu ◽  
Shuhe Chen ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastric Ulcer ◽  
Chronic Gastritis ◽  
Gastric Ulcers ◽  
Etoac Extract ◽  
Rat Paw Edema ◽  
Edema Model ◽  
Mouse Ear ◽  
Anti Inflammatory ◽  
Rat Paw

Chronic gastritis and gastric ulcers are prevalent throughout the world and are considered to be a global health problem. Modified Xiaochaihutang (MXCHT) prescription is broadly used in traditional medicine hospital for the treatment of gastritis. In order to assess the anti-Helicobacter pylori (H. pylori) effect of MXCHT, agar diffusion method in vitro and fluid dilution method for the minimal inhibitory concentration (MIC) were established. The anti-inflammatory effects were then evaluated using mouse ear edema model and rat paw edema model. The ethanol-induced gastric ulcer method was employed to verify the gastroprotective effect of active extracts in MXCHT. HPLC-TOF-MS/MS was used for analyzing the possible active constituents after oral administration of effective extracts in ethanol-induced gastric ulcer models. MXCHT and 4 different extracts of the bacterial inhibition diameter and MIC were dramatically decreased compared with control group, showing anti-Helicobacter pylori effects. High dose groups of MXCHT, water extract, EtOAc extract, and n-BuOH extract displayed significant anti-inflammatory effects in xylene-induced mouse ear edema model and carrageenan-induced rat paw edema model test. MXCHT and all active extracts exhibited gastroprotective activity and prevented gastric lesions induced by ethanol in rats. 4 prototype components and 4 metabolites were identified after oral administration of EtOAc extract. In addition, 6 prototype components and 6 metabolites were identified in n-BuOH extract. MXCHT, EtOAc extract, and n-BuOH extract demonstrate gastroprotective effects through anti-Helicobacter pylori and anti-inflammatory activities. Thus, this prescription may be a suitable natural source for the prevention and treatment of chronic gastritis and gastric ulcers.

scholarly journals Draft Genome Sequences of 42 Helicobacter pylori Isolates from Rural Regions of South India

2018 ◽  
Vol 6 (5) ◽  
Author(s):  
Vignesh Shetty ◽  
Binit Lamichhane ◽  
Eng-Guan Chua ◽  
Mamatha Ballal ◽  
Chin-Yen Tay
Keyword(s):  
Helicobacter Pylori ◽  
South India ◽  
Draft Genome ◽  
Rural Populations ◽  
Genome Sequences ◽  
Rural Regions ◽  
South Indian ◽  
Genetic Makeup ◽  
H Pylori ◽  
Development Of Gastric Cancer

ABSTRACT Helicobacter pylori is a successful human gastric pathogen that is associated with the development of gastric cancer. The draft genome sequences of 42 H. pylori clinical strains isolated from South Indian rural populations will provide further insights into the evolution and genetic makeup of Indian H. pylori strains.

Helicobacter pylori infestation in gastric ulcer disease

1994 ◽  
Vol 6 (8) ◽  
pp. 733-738
Author(s):  
Wiktor Laszewicz ◽  
Antoni Gabryelewicz ◽  
Pentti Sipponen ◽  
Max Siurala
Keyword(s):  
Helicobacter Pylori ◽  
Gastric Ulcer ◽  
Ulcer Disease
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