scholarly journals High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies

2016 ◽  
Vol 4 (6) ◽  
Author(s):  
Anina Buchmann ◽  
Michael Eitel ◽  
Pierre Koch ◽  
Paul N. Schwarz ◽  
Evi Stegmann ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Heterologous Expression ◽  
Gene Cluster ◽  
Genome Sequence ◽  
Draft Genome ◽  
Biosynthetic Gene Cluster ◽  
Draft Genome Sequence ◽  
Biosynthetic Gene ◽  
High Quality

The bacterium Nocardia terpenica IFM 0406 is known as the producer of the immunosuppressant brasilicardin A. Here, we report the completely sequenced genome of strain IFM 0406, which facilitates the heterologous expression of the brasilicardin biosynthetic gene cluster but also unveils the intriguing biosynthetic capacity of the strain to produce secondary metabolites.

scholarly journals Draft Genome Sequence of Linfuranone Producer Microbispora sp. GMKU 363

2015 ◽  
Vol 3 (6) ◽  
Author(s):  
Hisayuki Komaki ◽  
Natsuko Ichikawa ◽  
Akira Hosoyama ◽  
Nobuyuki Fujita ◽  
Arinthip Thamchaipenet ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Genome Sequence ◽  
Polyketide Synthase ◽  
Adipocyte Differentiation ◽  
Draft Genome ◽  
Biosynthetic Gene Cluster ◽  
Draft Genome Sequence ◽  
Biosynthetic Gene

Here, we report the draft genome sequence of Microbispora sp. GMKU 363, a plant-derived actinomycete that produces linfuranone A, a linear polyketide modified with a furanone ring possessing adipocyte differentiation inducing activity. The biosynthetic gene cluster for linfuranone was identified by analyzing polyketide synthase genes in the genome.

scholarly journals Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer

2016 ◽  
Vol 4 (5) ◽  
Author(s):  
Hisayuki Komaki ◽  
Akira Hosoyama ◽  
Natsuko Ichikawa ◽  
Yasuhiro Igarashi
Keyword(s):  
Genome Sequence ◽  
Cell Invasion ◽  
Draft Genome ◽  
Gene Clusters ◽  
Bioinformatic Analysis ◽  
Biosynthetic Gene Cluster ◽  
Tumor Cell Invasion ◽  
Draft Genome Sequence ◽  
Biosynthetic Gene ◽  
Streptomyces Sp

We report the draft genome sequence of Streptomyces sp. TP-A0874 isolated from compost. This strain produces catechoserine, a new catecholate-type inhibitor of tumor cell invasion. The genome harbors at least six gene clusters for polyketide and nonribosomal peptide biosyntheses. The biosynthetic gene cluster for catechoserines was identified by bioinformatic analysis.

scholarly journals Draft Genome Sequence of Geobacillus sp. LEMMY01, a Thermophilic Bacterium Isolated from the Site of a Burning Grass Pile

2017 ◽  
Vol 5 (19) ◽  
Author(s):  
Yuri Pinheiro Alves de Souza ◽  
Fábio Faria da Mota ◽  
Alexandre Soares Rosado
Keyword(s):  
Secondary Metabolites ◽  
Genome Sequence ◽  
Draft Genome ◽  
Axenic Culture ◽  
Gene Clusters ◽  
Thermophilic Bacterium ◽  
Draft Genome Sequence ◽  
Biosynthetic Gene ◽  
Biosynthetic Gene Clusters ◽  
Biotechnological Potential

ABSTRACT We report here the 3,586,065-bp draft genome of Geobacillus sp. LEMMY01, which was isolated (axenic culture) from a thermophilic chemolitoautotrophic consortium obtained from the site of a burning grass pile. The genome contains biosynthetic gene clusters coding for secondary metabolites, such as terpene and lantipeptide, confirming the biotechnological potential of this strain.

scholarly journals Draft Genome Sequence of Bacillus subtilis SB-14, an Antimicrobially Active Isolate from Namibian Social Spiders (Stegodyphus dumicola)

2019 ◽  
Vol 8 (25) ◽  
Author(s):  
Stine Sofie Frank Nielsen ◽  
Simone Weiss ◽  
Seven Nazipi ◽  
Ian P. G. Marshall ◽  
Trine Bilde ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Genome Sequence ◽  
Draft Genome ◽  
Gene Clusters ◽  
Draft Genome Sequence ◽  
Biosynthetic Gene ◽  
Biosynthetic Gene Clusters ◽  
High Quality ◽  
Social Spider ◽  
Content Type

We present the high-quality draft genome sequence of Bacillus subtilis SB-14, isolated from the Namibian social spider Stegodyphus dumicola. In accordance with its antimicrobial activity, both known and potentially novel antimicrobial biosynthetic gene clusters were identified in the genome of SB-14.

scholarly journals Draft Genome Sequence of Thermogemmatispora onikobensis NBRC 111776 T , an Aerial Mycelium- and Spore-Forming Thermophilic Bacterium Belonging to the Class Ktedonobacteria

2016 ◽  
Vol 4 (5) ◽  
Author(s):  
Hisayuki Komaki ◽  
Akira Hosoyama ◽  
Shuhei Yabe ◽  
Akira Yokota ◽  
Yoshihito Uchino ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Genome Sequence ◽  
Draft Genome ◽  
Aerial Mycelium ◽  
Gene Clusters ◽  
Thermophilic Bacterium ◽  
Draft Genome Sequence ◽  
Biosynthetic Gene ◽  
Biosynthetic Gene Clusters ◽  
Nonribosomal Peptide

Here, we report the draft genome sequence of Thermogemmatispora onikobensis NBRC 111776 T , an aerial mycelium- and spore-forming thermophilic bacterium belonging to the class Ktedonobacteria . The genome contains five biosynthetic gene clusters coding for secondary metabolites, such as terpene, thiopeptide, lantipeptide, nonribosomal peptide, and lassopeptide, suggesting the potential to produce secondary metabolites.

scholarly journals Draft Genome Sequence of the Novonestmycin-Producing Strain Streptomyces sp. Z26, Isolated from Potato Rhizosphere in Morocco

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Anina Buchmann ◽  
Carolina Cano-Prieto ◽  
Ahmed Nafis ◽  
Mustapha Barakate ◽  
Mohamed Baz ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Secondary Metabolites ◽  
Gene Cluster ◽  
Draft Genome ◽  
Production Capacity ◽  
Biosynthetic Gene Cluster ◽  
Biosynthetic Gene ◽  
Content Type ◽  
Streptomyces Sp ◽  
Insight Into

Streptomyces sp. strain Z26 exhibited antifungal activity and turned out to be a producer of the secondary metabolites novonestmycin A and B. The 6.5-Mb draft genome gives insight into the complete secondary metabolite production capacity and builds the basis to find and locate the biosynthetic gene cluster encoding the novonestmycins.

scholarly journals EngineeredStreptomyces avermitilisHost for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites

2013 ◽  
Vol 2 (7) ◽  
pp. 384-396 ◽  
Author(s):  
Mamoru Komatsu ◽  
Kyoko Komatsu ◽  
Hanae Koiwai ◽  
Yuuki Yamada ◽  
Ikuko Kozone ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Heterologous Expression ◽  
Gene Cluster ◽  
Biosynthetic Gene Cluster ◽  
Biosynthetic Gene

scholarly journals Identification and Verification of the Prodigiosin Biosynthetic Gene Cluster (BGC) in Pseudoalteromonas rubra S4059

2021 ◽  
Author(s):  
Xiyan Wang ◽  
Thomas Isbrandt ◽  
Emil Ørsted Christensen ◽  
Jette Melchiorsen ◽  
Thomas Ostenfeld Larsen ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Heterologous Expression ◽  
Gene Cluster ◽  
Genome Mining ◽  
Gene Clusters ◽  
Biosynthetic Gene Cluster ◽  
Biosynthetic Gene ◽  
Biosynthetic Gene Clusters ◽  
Pseudoalteromonas Rubra

Pigmented Pseudoalteromonas strains are renowned for their production of secondary metabolites, and genome mining has revealed a high number of biosynthetic gene clusters (BGCs) for which the chemistry is unknown. Identification of those BGCs is a prerequisite for linking products to gene clusters and for further exploitation through heterologous expression.

scholarly journals Draft Genome Sequence of Clostridium cochlearium Strain AGROS13, Isolated from a Sheep Dairy Farm in New Zealand

2020 ◽  
Vol 9 (26) ◽  
Author(s):  
Tanushree B. Gupta ◽  
Paul Maclean ◽  
Ruy Jauregui ◽  
Alexis N. Risson ◽  
Gale Brightwell
Keyword(s):  
New Zealand ◽  
Genome Sequence ◽  
Draft Genome ◽  
Gc Content ◽  
Dairy Farm ◽  
Biosynthetic Gene Cluster ◽  
Draft Genome Sequence ◽  
Biosynthetic Gene ◽  
Content Type ◽  
Clostridium Cochlearium

ABSTRACT We report the draft genome sequence of a new Clostridium cochlearium strain, AGROS13, which was isolated from a sheep dairy farm environment in New Zealand. The genome is 2.7 Mbp, with a GC content of 28.2%. The genome sequence was found to be closely related to that of Clostridium cochlearium ATCC 17787. The new strain harbors a biosynthetic gene cluster coding for an unknown sactipeptide.

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