scholarly journals Transcriptional regulation of the Enterococcus faecium BM4147 vancomycin resistance gene cluster by the VanS-VanR two-component regulatory system in Escherichia coli K-12.

1997 ◽  
Vol 179 (18) ◽  
pp. 5903-5913 ◽  
Author(s):  
A Haldimann ◽  
S L Fisher ◽  
L L Daniels ◽  
C T Walsh ◽  
B L Wanner
Keyword(s):  
Escherichia Coli ◽  
Transcriptional Regulation ◽  
Gene Cluster ◽  
Resistance Gene ◽  
Enterococcus Faecium ◽  
Regulatory System ◽  
Vancomycin Resistance ◽  
Resistance Gene Cluster ◽  
Two Component ◽  
K 12

scholarly journals The Biopesticide Paenibacillus popilliae Has a Vancomycin Resistance Gene Cluster Homologous to the Enterococcal VanA Vancomycin Resistance Gene Cluster

2000 ◽  
Vol 44 (3) ◽  
pp. 705-709 ◽  
Author(s):  
Robin Patel ◽  
Kerryl Piper ◽  
Franklin R. Cockerill ◽  
James M. Steckelberg ◽  
Allan A. Yousten
Keyword(s):  
Gene Cluster ◽  
Resistance Gene ◽  
Bacterial Resistance ◽  
Vancomycin Resistance ◽  
Amino Acid Sequences ◽  
Agricultural Practice ◽  
Human Pathogens ◽  
Resistance Gene Cluster ◽  
Genes Encoding ◽  
Vancomycin Resistant

ABSTRACT We have previously identified, in Paenibacillus popilliae, a 708-bp sequence which has homology to the sequence of the enterococcal vanA gene. We have performed further studies revealing five genes encoding homologues of VanY, VanZ, VanH, VanA, and VanX in P. popilliae. The predicted amino acid sequences are similar to those in VanA vancomycin-resistant enterococci: 61% identity for VanY, 21% for VanZ, 74% for VanH, 77% for VanA, and 79% for VanX. The genes in P. popilliae may have been a precursor to or have had ancestral genes in common with vancomycin resistance genes in enterococci. The use of P. popilliae biopesticidal preparations in agricultural practice may have an impact on bacterial resistance in human pathogens.

scholarly journals Vancomycin-resistance gene cluster, vanC, in the gut microbiome of acute leukemia patients undergoing intensive chemotherapy

PLoS ONE ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. e0223890 ◽  
Author(s):  
Armin Rashidi ◽  
Zhigang Zhu ◽  
Thomas Kaiser ◽  
Dawn A. Manias ◽  
Shernan G. Holtan ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Gene Cluster ◽  
Resistance Gene ◽  
Gut Microbiome ◽  
Vancomycin Resistance ◽  
Intensive Chemotherapy ◽  
Resistance Gene Cluster

scholarly journals Identification of a Copper-Responsive Two-Component System on the Chromosome of Escherichia coli K-12

2000 ◽  
Vol 182 (20) ◽  
pp. 5864-5871 ◽  
Author(s):  
George P. Munson ◽  
Deborah L. Lam ◽  
F. Wayne Outten ◽  
Thomas V. O'Halloran
Keyword(s):  
Escherichia Coli ◽  
Pseudomonas Syringae ◽  
Metal Ion ◽  
Copper Ions ◽  
Copper Ion ◽  
Regulatory System ◽  
Copper Resistance ◽  
E Coli ◽  
Two Component ◽  
K 12

ABSTRACT Using a genetic screen we have identified two chromosomal genes,cusRS (ylcA ybcZ), from Escherichia coli K-12 that encode a two-component, signal transduction system that is responsive to copper ions. This regulatory system is required for copper-induced expression of pcoE, a plasmid-borne gene from the E. coli copper resistance operon pco. The closest homologs of CusR and CusS are plasmid-borne two-component systems that are also involved in metal responsive gene regulation: PcoR and PcoS from the pcooperon of E. coli; CopR and CopS from thecop operon, which provides copper resistance toPseudomonas syringae; and SilR and SilS from thesil locus, which provides silver ion resistance toSalmonella enterica serovar Typhimurium. The genescusRS are also required for the copper-dependent expression of at least one chromosomal gene, designated cusC(ylcB), which is allelic to the recently identified virulence gene ibeB in E. coli K1. Thecus locus may comprise a copper ion efflux system, because the expression of cusC is induced by high concentrations of copper ions. Furthermore, the translation products of cusCand additional downstream genes are homologous to known metal ion antiporters.

Transcriptome analysis of all two-component regulatory system mutants of Escherichia coli K-12

2002 ◽  
Vol 46 (1) ◽  
pp. 281-291 ◽  
Author(s):  
Taku Oshima ◽  
Hirofumi Aiba ◽  
Yasushi Masuda ◽  
Shigehiko Kanaya ◽  
Masahito Sugiura ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Transcriptome Analysis ◽  
Regulatory System ◽  
Two Component ◽  
K 12

scholarly journals Aminoglycoside-Streptothricin Resistance Gene Cluster aadE–sat4–aphA-3 Disseminated among Multiresistant Isolates of Enterococcus faecium

2001 ◽  
Vol 45 (11) ◽  
pp. 3267-3269 ◽  
Author(s):  
Guido Werner ◽  
Bianca Hildebrandt ◽  
Wolfgang Witte
Keyword(s):  
Gene Cluster ◽  
Resistance Gene ◽  
Enterococcus Faecium ◽  
Campylobacter Coli ◽  
Genomic Fragment ◽  
Resistance Gene Cluster ◽  
Pcr Products ◽  
Different Origins

ABSTRACT Seventy-two Enterococcus faecium isolates of different origins highly resistant to nourseothricin and streptomycin were studied. Sequencing of a genomic fragment from two isolates identified a gene cluster,aadE– sat4–aphA-3, which has been isolated recently in staphylococci and Campylobacter coli. Patterns of digested PCR products ofaadE–sat4–aphA-3 were identical for all isolates.

Sign in / Sign up

Export Citation Format

Share Document